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Academic Journal

Diethylhexyl phthalate (DEHP) regulates the proliferation and chemosensitivity of esophageal squamous cell carcinoma cells via regulation of PTEN.

  • Authors : Zhu J; Department of Gastroenterology, Jingjiang People's Hospital, Jingjiang, Jiangsu, 214500, People's Republic of China.; Zhang X

Subjects: Genes, Tumor Suppressor*; Antineoplastic Agents/Antineoplastic Agents/Antineoplastic Agents/*pharmacology ; Cell Proliferation/Cell Proliferation/Cell Proliferation/*drug effects

  • Source: Human cell [Hum Cell] 2021 Jul; Vol. 34 (4), pp. 1153-1162. Date of Electronic Publication: 2021 Mar 15.Publisher: Springer Country of Publication: Japan NLM ID: 8912329 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1749-0774

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Academic Journal

Dual targeting of Notch and Wnt/β-catenin pathways: Potential approach in triple-negative breast cancer treatment.

  • Authors : Nasser F; Department of Biotechnology, Institute of Graduate Studies and Research, Alexandria University, Alexandria, Egypt.; Moussa N

Subjects: Antineoplastic Agents/Antineoplastic Agents/Antineoplastic Agents/*pharmacology ; Bridged Bicyclo Compounds, Heterocyclic/Bridged Bicyclo Compounds, Heterocyclic/Bridged Bicyclo Compounds, Heterocyclic/*pharmacology ; Pyrimidinones/Pyrimidinones/Pyrimidinones/*pharmacology

  • Source: Naunyn-Schmiedeberg's archives of pharmacology [Naunyn Schmiedebergs Arch Pharmacol] 2021 Mar; Vol. 394 (3), pp. 481-490. Date of Electronic Publication: 2020 Oct 14.Publisher: Springer Verlag Country of Publication: Germany NLM ID: 0326264 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

MDM2 inhibition improves cisplatin-induced renal injury in mice via inactivation of Notch/hes1 signaling pathway.

  • Authors : Luo X; Department of Pharmacology, Cangzhou Central Hospital, Cangzhou, China.; Zhang L

Subjects: Antineoplastic Agents/Antineoplastic Agents/Antineoplastic Agents/*toxicity ; Cisplatin/Cisplatin/Cisplatin/*toxicity ; Kidney Diseases/Kidney Diseases/Kidney Diseases/*chemically induced

  • Source: Human & experimental toxicology [Hum Exp Toxicol] 2021 Feb; Vol. 40 (2), pp. 369-379. Date of Electronic Publication: 2020 Aug 28.Publisher: SAGE Publications Country of Publication: England NLM ID: 9004560 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Ginsenoside Rg3 Suppresses Epithelial-Mesenchymal Transition via Downregulating Notch-Hes1 Signaling in Colon Cancer Cells.

  • Authors : Li X; Department of Gastroenterology, West China Hospital of Sichuan University, Chengdu, P. R. China.; Liu W

Subjects: Antineoplastic Agents*; Colonic Neoplasms/Colonic Neoplasms/Colonic Neoplasms/*genetics ; Colonic Neoplasms/Colonic Neoplasms/Colonic Neoplasms/*pathology

  • Source: The American journal of Chinese medicine [Am J Chin Med] 2021; Vol. 49 (1), pp. 217-235. Date of Electronic Publication: 2020 Dec 26.Publisher: World Scientific Pub Country of Publication: Singapore NLM ID: 7901431 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

The prognostic implications of Notch1, Hes1, Ascl1, and DLL3 protein expression in SCLC patients receiving platinum-based chemotherapy.

  • Authors : Tendler S; Department of Oncology-Pathology, Karolinska Institutet, Stockholm, Sweden.; Theme Cancer, Patient Area Head and Neck, Lung, and Skin Cancer, Karolinska University Hospital, Stockholm, Sweden.

Subjects: Antineoplastic Agents/Antineoplastic Agents/Antineoplastic Agents/*therapeutic use ; Biomarkers, Tumor/Biomarkers, Tumor/Biomarkers, Tumor/*metabolism ; Lung Neoplasms/Lung Neoplasms/Lung Neoplasms/*drug therapy

  • Source: PloS one [PLoS One] 2020 Oct 26; Vol. 15 (10), pp. e0240973. Date of Electronic Publication: 2020 Oct 26 (Print Publication: 2020).Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: eCollection Cited Medium: Internet

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Academic Journal

Sequential combination of cisplatin with eugenol targets ovarian cancer stem cells through the Notch-Hes1 signalling pathway.

  • Authors : Islam SS; Cancer Biology and Experimental Therapeutics, Department of Molecular Oncology, King Faisal Specialist Hospital and Research Centre, Riyadh, Saudi Arabia.; Aboussekhra A

Subjects: Anti-Infective Agents/Anti-Infective Agents/Anti-Infective Agents/*therapeutic use ; Antineoplastic Agents/Antineoplastic Agents/Antineoplastic Agents/*therapeutic use ; Cisplatin/Cisplatin/Cisplatin/*therapeutic use

  • Source: Journal of experimental & clinical cancer research : CR [J Exp Clin Cancer Res] 2019 Aug 30; Vol. 38 (1), pp. 382. Date of Electronic Publication: 2019 Aug 30.Publisher: BioMed Central Country of Publication: England NLM ID: 8308647 Publication Model: Electronic Cited Medium: Internet ISSN: 1756-9966

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Academic Journal

[Expression Levels of JARID1B, Hes1 and MMP-9 Genes in CML Patients Treated with Imatinib Mesylate].

  • Authors : He ZK; Institute of Basic Medical Sciences, School of Basic Medical Sciences, Hubei University of Medicine, Shiyan 442000, Hubei Province, China.; Xue S

Subjects: Leukemia, Myelogenous, Chronic, BCR-ABL Positive*/Leukemia, Myelogenous, Chronic, BCR-ABL Positive*/Leukemia, Myelogenous, Chronic, BCR-ABL Positive*/drug therapy; Antineoplastic Agents/Antineoplastic Agents/Antineoplastic Agents/*therapeutic use ; Imatinib Mesylate/Imatinib Mesylate/Imatinib Mesylate/*therapeutic use

  • Source: Zhongguo shi yan xue ye xue za zhi [Zhongguo Shi Yan Xue Ye Xue Za Zhi] 2019 Aug; Vol. 27 (4), pp. 1071-1076.Publisher: Zhongguo shi yan xue za zhi she Country of Publication: China NLM ID: 101084424 Publication Model: Print Cited Medium: Print ISSN:

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Academic Journal

Cancer Stem Cell Biomarkers in EGFR-Mutation-Positive Non-Small-Cell Lung Cancer.

  • Authors : Codony-Servat J; Pangaea Oncology, Laboratory of Molecular Biology, Quirón-Dexeus University Institute, Barcelona, Spain. Electronic address: .; Codony-Servat C

Subjects: Aldehyde Dehydrogenase 1 Family/Aldehyde Dehydrogenase 1 Family/Aldehyde Dehydrogenase 1 Family/*metabolism ; Antineoplastic Agents/Antineoplastic Agents/Antineoplastic Agents/*therapeutic use ; Biomarkers, Tumor/Biomarkers, Tumor/Biomarkers, Tumor/*metabolism

  • Source: Clinical lung cancer [Clin Lung Cancer] 2019 May; Vol. 20 (3), pp. 167-177. Date of Electronic Publication: 2019 Feb 21.Publisher: Elsevier Country of Publication: United States NLM ID: 100893225 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Small-molecule screening yields a compound that inhibits the cancer-associated transcription factor Hes1 via the PHB2 chaperone.

  • Authors : Perron A; Institute for Chemical Research, Kyoto University, Uji, Kyoto 611-0011; Institute for Integrated Cell-Material Sciences (iCeMS), Kyoto University, Uji, Kyoto 611-0011.

Subjects: High-Throughput Screening Assays*; Antineoplastic Agents/Antineoplastic Agents/Antineoplastic Agents/*pharmacology ; Apoptosis/Apoptosis/Apoptosis/*drug effects

  • Source: The Journal of biological chemistry [J Biol Chem] 2018 May 25; Vol. 293 (21), pp. 8285-8294. Date of Electronic Publication: 2018 Mar 09.Publisher: Elsevier Inc. on behalf of American Society for Biochemistry and Molecular Biology Country of Publication: United States NLM ID: 2985121R Publication

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