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Academic Journal

Mono- and bis(steroids) containing a cyclooctane core: Synthesis, antiproliferative activity, and action on cell cytoskeleton microtubules.

Subjects: Microtubules*/Microtubules*/Microtubules*/drug effects ; Cell Proliferation*/Cell Proliferation*/Cell Proliferation*/drug effects ; Antineoplastic Agents*/Antineoplastic Agents*/Antineoplastic Agents*/pharmacology

  • Source: Archiv der Pharmazie [Arch Pharm (Weinheim)] 2024 Nov; Vol. 357 (11), pp. e2400483. Date of Electronic Publication: 2024 Jul 30.Publisher: Wiley-VCH Verlag GmbH & Co. KGaA Country of Publication: Germany NLM ID: 0330167 Publication Model: Print-Electronic Cited Medium: Internet

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Academic Journal

Pelophen B is a non-taxoid binding microtubule-stabilizing agent with promising preclinical anticancer properties.

  • Authors : Vermeulen S; Laboratory of Experimental Cancer Research, Department of Human Structure and Repair, Ghent University, Ghent, Belgium.; Cancer Research Institute Ghent, Ghent, Belgium.

Subjects: Microtubules*/Microtubules*/Microtubules*/metabolism ; Microtubules*/Microtubules*/Microtubules*/drug effects ; Paclitaxel*/Paclitaxel*/Paclitaxel*/pharmacology

  • Source: Scientific reports [Sci Rep] 2024 Dec 04; Vol. 14 (1), pp. 30188. Date of Electronic Publication: 2024 Dec 04.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN:

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Academic Journal

5H-benzo[c]fluorene derivative exhibits antiproliferative activity via microtubule destabilization.

  • Authors : Fatima E; CSIR-Central Institute of Medicinal and Aromatic Plants, P.O. CIMAP, Lucknow 226015, India; Academy of Scientific and Innovative Research (AcSIR), Ghaziabad, U.P. 201002, India.

Subjects: Antineoplastic Agents*/Antineoplastic Agents*/Antineoplastic Agents*/pharmacology ; Antineoplastic Agents*/Antineoplastic Agents*/Antineoplastic Agents*/chemistry ; Antineoplastic Agents*/Antineoplastic Agents*/Antineoplastic Agents*/chemical synthesis

  • Source: Bioorganic chemistry [Bioorg Chem] 2024 Dec; Vol. 153, pp. 107891. Date of Electronic Publication: 2024 Oct 18.Publisher: Elsevier Country of Publication: United States NLM ID: 1303703 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

A potent Bioorganic azapodophyllotoxin derivative Suppresses tumor Progression in Triple negative breast Cancer: An Insight into its Inhibitory effect on tubulin polymerization and Disruptive effect on microtubule assembly.

  • Authors : Gupta S; Department of Chemistry, Visvesvaraya National Institute of Technology, Nagpur 440010, Maharashtra, India.; Dev J R A

Subjects: Triple Negative Breast Neoplasms*/Triple Negative Breast Neoplasms*/Triple Negative Breast Neoplasms*/drug therapy ; Triple Negative Breast Neoplasms*/Triple Negative Breast Neoplasms*/Triple Negative Breast Neoplasms*/pathology ; Triple Negative Breast Neoplasms*/Triple Negative Breast Neoplasms*/Triple Negative Breast Neoplasms*/metabolism

  • Source: Bioorganic chemistry [Bioorg Chem] 2024 Dec; Vol. 153, pp. 107839. Date of Electronic Publication: 2024 Sep 21.Publisher: Elsevier Country of Publication: United States NLM ID: 1303703 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Disturbing microtubule-endoplasmic reticulum dynamics by gold nanoclusters for improved triple-negative breast cancer treatment.

  • Authors : Cao K; Department of Chemistry, College of Chemistry and Life Science, Center of Excellence for Environmental Safety and Biological Effects, Beijing University of Technology, Beijing 100124, China. .; Luo K

Subjects: Triple Negative Breast Neoplasms*/Triple Negative Breast Neoplasms*/Triple Negative Breast Neoplasms*/drug therapy ; Triple Negative Breast Neoplasms*/Triple Negative Breast Neoplasms*/Triple Negative Breast Neoplasms*/pathology ; Gold*/Gold*/Gold*/chemistry

  • Source: Journal of materials chemistry. B [J Mater Chem B] 2024 Nov 20; Vol. 12 (45), pp. 11648-11658. Date of Electronic Publication: 2024 Nov 20.Publisher: Royal Society of Chemistry Country of Publication: England NLM ID: 101598493 Publication Model: Electronic Cited Medium: Internet ISSN:

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Academic Journal

3-nitropyridine analogues as novel microtubule-targeting agents.

  • Authors : Herman J; 4AZA Biosciences, Leuven, Belgium.; Interface Valorisation Platform (IVAP), KU Leuven, Leuven, Belgium.

Subjects: Microtubules*/Microtubules*/Microtubules*/drug effects ; Microtubules*/Microtubules*/Microtubules*/metabolism ; Tubulin*/Tubulin*/Tubulin*/metabolism

  • Source: PloS one [PLoS One] 2024 Nov 07; Vol. 19 (11), pp. e0307153. Date of Electronic Publication: 2024 Nov 07 (Print Publication: 2024).Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: eCollection Cited Medium: Internet

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Academic Journal

Identification of 3-Aryl-1-benzotriazole-1-yl-acrylonitrile as a Microtubule-Targeting Agent (MTA) in Solid Tumors.

  • Authors : Zoroddu S; Department of Biomedical Sciences, University of Sassari, 07100 Sassari, Italy.; Sanna L

Subjects: Microtubules*/Microtubules*/Microtubules*/drug effects ; Microtubules*/Microtubules*/Microtubules*/metabolism ; Antineoplastic Agents*/Antineoplastic Agents*/Antineoplastic Agents*/pharmacology

  • Source: International journal of molecular sciences [Int J Mol Sci] 2024 May 24; Vol. 25 (11). Date of Electronic Publication: 2024 May 24.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067

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Development of Potent Microtubule Targeting Agent by Structural Simplification of Natural Diazonamide.

  • Authors : Kalnins T; Latvian Institute of Organic Synthesis, Aizkraukles 21, Riga LV-1006, Latvia.; Vitkovska V

Subjects: Tubulin Modulators*/Tubulin Modulators*/Tubulin Modulators*/pharmacology ; Tubulin Modulators*/Tubulin Modulators*/Tubulin Modulators*/chemistry ; Tubulin Modulators*/Tubulin Modulators*/Tubulin Modulators*/chemical synthesis

  • Source: Journal of medicinal chemistry [J Med Chem] 2024 Jun 13; Vol. 67 (11), pp. 9227-9259. Date of Electronic Publication: 2024 Jun 04.Publisher: American Chemical Society Country of Publication: United States NLM ID: 9716531 Publication Model: Print-Electronic Cited Medium: Internet

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Academic Journal

An update on the development on tubulin inhibitors for the treatment of solid tumors.

  • Authors : Yakkala PA; Department of Pharmaceutical Chemistry, School of Pharmaceutical Education and Research, Jamia Hamdard, New Delhi, India.; Rahaman S

Subjects: Neoplasms*/Neoplasms*/Neoplasms*/drug therapy ; Neoplasms*/Neoplasms*/Neoplasms*/pathology ; Drug Development*

  • Source: Expert opinion on therapeutic targets [Expert Opin Ther Targets] 2024 Mar; Vol. 28 (3), pp. 193-220. Date of Electronic Publication: 2024 Apr 22.Publisher: Informa Healthcare Country of Publication: England NLM ID: 101127833 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

New Combretastatin Analogs as Anticancer Agents: Design, Synthesis, Microtubules Polymerization Inhibition, and Molecular Docking Studies.

Subjects: Antineoplastic Agents*/Antineoplastic Agents*/Antineoplastic Agents*/chemistry ; Antineoplastic Agents*/Antineoplastic Agents*/Antineoplastic Agents*/pharmacology ; Microtubules*/Microtubules*/Microtubules*/drug effects

  • Source: Chemistry & biodiversity [Chem Biodivers] 2023 Apr; Vol. 20 (4), pp. e202201206. Date of Electronic Publication: 2023 Mar 08.Publisher: Verlag Helvetica Chimica Acta Country of Publication: Switzerland NLM ID: 101197449 Publication Model: Print-Electronic Cited Medium:

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  • 1-10 of  5,356 results for ""Microtubules""