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Academic Journal

Oxaliplatin lipidated prodrug synergistically enhances the anti-colorectal cancer effect of IL12 mRNA.

  • Authors : Liu H; School of Pharmacy, Collaborative Innovation Center of Advanced Drug Delivery System and Biotech Drugs, Universities of Shandong, Key Laboratory of Molecular Pharmacology and Drug Evaluation (Yantai University), Ministry of Education, Yantai University, Yantai, 264005, China.; Yantai Key Laboratory of Nanomedicine & Advanced Preparations, Yantai Institute of Materia Medica, Yantai, 264000, China.

Subjects: Oxaliplatin*/Oxaliplatin*/Oxaliplatin*/administration & dosage ; Oxaliplatin*/Oxaliplatin*/Oxaliplatin*/pharmacology ; Oxaliplatin*/Oxaliplatin*/Oxaliplatin*/pharmacokinetics

  • Source: Drug delivery and translational research [Drug Deliv Transl Res] 2024 Nov; Vol. 14 (11), pp. 3186-3199. Date of Electronic Publication: 2024 Mar 08.Publisher: Springer Country of Publication: United States NLM ID: 101540061 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

The repeated administration of rhIL-12 for 14 weeks in rhesus monkeys: A toxicity assessment.

  • Authors : Ding H; School of Basic Medical Sciences, Qingdao University, Qingdao, China.; Kanglitai Biopharmaceutical (Qingdao) Co., Ltd., Qingdao, China.

Subjects: Interleukin-12*/Interleukin-12*/Interleukin-12*/toxicity ; Antineoplastic Agents*; Animals

  • Source: Journal of applied toxicology : JAT [J Appl Toxicol] 2024 Feb; Vol. 44 (2), pp. 301-312. Date of Electronic Publication: 2023 Sep 28.Publisher: John Wiley And Sons Country of Publication: England NLM ID: 8109495 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Localized Interleukin-12 for Cancer Immunotherapy.

  • Authors : Nguyen KG; Joint Department of Biomedical Engineering, University of North Carolina, Chapel Hill and North Carolina State University, Raleigh, NC, United States.; Vrabel MR

Subjects: Genetic Therapy*/Genetic Therapy*/Genetic Therapy*/adverse effects ; Immunotherapy*/Immunotherapy*/Immunotherapy*/adverse effects; Antineoplastic Agents/Antineoplastic Agents/Antineoplastic Agents/*administration & dosage

  • Source: Frontiers in immunology [Front Immunol] 2020 Oct 15; Vol. 11, pp. 575597. Date of Electronic Publication: 2020 Oct 15 (Print Publication: 2020).Publisher: Frontiers Research Foundation] Country of Publication: Switzerland NLM ID: 101560960 Publication Model: eCollection Cited Medium: Internet

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Academic Journal

A Review of Clinical and Preclinical Studies on Therapeutic Strategies Using Interleukin-12 in Cancer Therapy and the Protective Role of Interleukin-12 in Hematological Recovery in Chemoradiotherapy.

  • Authors : Li P; Department of Pharmacy, The Affiliated Hospital of Qingdao University, Qingdao, Shandong, China (mainland).; Zhang H

Subjects: Antineoplastic Agents/Antineoplastic Agents/Antineoplastic Agents/*therapeutic use ; Chemoradiotherapy/Chemoradiotherapy/Chemoradiotherapy/*adverse effects ; Hematopoiesis/Hematopoiesis/Hematopoiesis/*drug effects

  • Source: Medical science monitor : international medical journal of experimental and clinical research [Med Sci Monit] 2020 Aug 19; Vol. 26, pp. e923855. Date of Electronic Publication: Publisher: International Scientific Information, Inc Country of Publication: United States NLM ID: 9609063 Publication Model: Electronic Cited Medium:

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Academic Journal

An in silico exploration of combining Interleukin-12 with Oxaliplatin to treat liver-metastatic colorectal cancer.

  • Authors : Wang Q; Department of Computer Sciences, Mathematics, and Engineering, Shepherd University, Shepherdstown, 25443, WV, USA.; Wang Z

Subjects: Models, Theoretical*; Antineoplastic Agents/Antineoplastic Agents/Antineoplastic Agents/*pharmacology ; Colorectal Neoplasms/Colorectal Neoplasms/Colorectal Neoplasms/*pathology

  • Source: BMC cancer [BMC Cancer] 2020 Jan 08; Vol. 20 (1), pp. 26. Date of Electronic Publication: 2020 Jan 08.Publisher: BioMed Central Country of Publication: England NLM ID: 100967800 Publication Model: Electronic Cited Medium: Internet ISSN: 1471-2407

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Academic Journal

Tumor Microenvironment-Triggered Charge Reversal Polymetformin-Based Nanosystem Co-Delivered Doxorubicin and IL-12 Cytokine Gene for Chemo-Gene Combination Therapy on Metastatic Breast Cancer.

  • Authors : Sun Y; Department of Pharmaceutics, School of Pharmacy, Ningxia Medical University, No. 1160, Shengli Street, Yinchuan 750004, China.; Liu L

Subjects: Drug Delivery Systems*; Antineoplastic Agents/Antineoplastic Agents/Antineoplastic Agents/*pharmacology ; Breast Neoplasms/Breast Neoplasms/Breast Neoplasms/*therapy

  • Source: ACS applied materials & interfaces [ACS Appl Mater Interfaces] 2020 Oct 14; Vol. 12 (41), pp. 45873-45890. Date of Electronic Publication: 2020 Sep 29.Publisher: American Chemical Society Country of Publication: United States NLM ID: 101504991 Publication Model: Print-Electronic Cited Medium: Internet

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Academic Journal

Re-designing Interleukin-12 to enhance its safety and potential as an anti-tumor immunotherapeutic agent.

  • Authors : Wang P; Sino-British Research Centre for Molecular Oncology, National Centre for International Research in Cell and Gene Therapy, School of Basic Medical Sciences, Academy of Medical Sciences, Zhengzhou University, 450052, Zhengzhou, China.; Li X

Subjects: Antineoplastic Agents/Antineoplastic Agents/Antineoplastic Agents/*pharmacology ; Immunotherapy/Immunotherapy/Immunotherapy/*methods ; Interleukin-12/Interleukin-12/Interleukin-12/*immunology

  • Source: Nature communications [Nat Commun] 2017 Nov 09; Vol. 8 (1), pp. 1395. Date of Electronic Publication: 2017 Nov 09.Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN:

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Academic Journal

IL-12 inhibits postoperative residual tumor growth in murine models of sarcoma and renal carcinoma.

  • Authors : Ding H; School of Basic Medical Sciences, Qingdao University.; Kanglitai Pharmaceutical Co., Ltd., Qingdao, Shandong.

Subjects: Antineoplastic Agents/Antineoplastic Agents/Antineoplastic Agents/*pharmacology ; Interleukin-12/Interleukin-12/Interleukin-12/*pharmacology ; Kidney Neoplasms/Kidney Neoplasms/Kidney Neoplasms/*drug therapy

  • Source: Anti-cancer drugs [Anticancer Drugs] 2021 Nov 01; Vol. 32 (10), pp. 1003-1010.Publisher: Lippincott Williams & Wilkins Country of Publication: England NLM ID: 9100823 Publication Model: Print Cited Medium: Internet ISSN:

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Academic Journal

Safety and antitumor effect of oncolytic and helper-dependent adenoviruses expressing interleukin-12 variants in a hamster pancreatic cancer model.

  • Authors : Poutou J; Gene Therapy Program CIMA, Foundation for Applied Medical Research, IDISNA, University of Navarra, Pamplona, Spain.; Bunuales M

Subjects: Disease Models, Animal*; Adenoviridae/Adenoviridae/Adenoviridae/*metabolism ; Antineoplastic Agents/Antineoplastic Agents/Antineoplastic Agents/*adverse effects

  • Source: Gene therapy [Gene Ther] 2015 Sep; Vol. 22 (9), pp. 696-706. Date of Electronic Publication: 2015 May 04.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 9421525 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

A fully-virulent retargeted oncolytic HSV armed with IL-12 elicits local immunity and vaccine therapy towards distant tumors.

  • Authors : Leoni V; Department of Experimental, Diagnostic and Specialty Medicine, University of Bologna, Bologna, Italy.; Vannini A

Subjects: Interleukin-12* ; Simplexvirus*; Antineoplastic Agents/Antineoplastic Agents/Antineoplastic Agents/*pharmacology

  • Source: PLoS pathogens [PLoS Pathog] 2018 Aug 06; Vol. 14 (8), pp. e1007209. Date of Electronic Publication: 2018 Aug 06 (Print Publication: 2018).Publisher: Public Library of Science Country of Publication: United States NLM ID: 101238921 Publication Model: eCollection Cited Medium: Internet

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  • 1-10 of  1,274 results for ""INTERLEUKIN-12""