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An insight into biological activities of native cyclotides for potential applications in agriculture and pharmaceutics.

• Authors : Grover T; Bioinformatics Infrastructure Facility, Gargi College, University of Delhi, India.; Mishra R

Subjects: Anti-Infective Agents/Anti-Infective Agents/Anti-Infective Agents/*chemistry ; Antineoplastic Agents/Antineoplastic Agents/Antineoplastic Agents/*chemistry ; Cyclotides/Cyclotides/Cyclotides/*chemistry

• Source: Peptides [Peptides] 2021 Jan; Vol. 135, pp. 170430. Date of Electronic Publication: 2020 Oct 20.Publisher: Elsevier Science Inc Country of Publication: United States NLM ID: 8008690 Publication Model: Print-Electronic Cited Medium: Internet

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Isolation and characterization of cytotoxic cyclotides from Viola tricolor.

• Authors : Tang J; State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, 132# Lanhei Road, Heilongtan, Kunming 650204, Yunnan, PR China.; Wang CK

Subjects: Antineoplastic Agents/Antineoplastic Agents/Antineoplastic Agents/*isolation & purification ; Antineoplastic Agents/Antineoplastic Agents/Antineoplastic Agents/*pharmacology ; Cyclotides/Cyclotides/Cyclotides/*isolation & purification

• Source: Peptides [Peptides] 2010 Aug; Vol. 31 (8), pp. 1434-40. Date of Electronic Publication: 2010 May 16.Publisher: Elsevier Science Inc Country of Publication: United States NLM ID: 8008690 Publication Model: Print-Electronic Cited Medium: Internet

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Cyclotides, a novel ultrastable polypeptide scaffold for drug discovery.

• Authors : Gould A; Department of Pharmacology and Pharmaceutical Sciences, School of Pharmacy, University of Southern California, Los Angeles, CA 90033, USA.; Ji Y

Subjects: Anti-Infective Agents*/Anti-Infective Agents*/Anti-Infective Agents*/chemical synthesis ; Anti-Infective Agents*/Anti-Infective Agents*/Anti-Infective Agents*/isolation & purification ; Anti-Infective Agents*/Anti-Infective Agents*/Anti-Infective Agents*/pharmacology

• Source: Current pharmaceutical design [Curr Pharm Des] 2011 Dec; Vol. 17 (38), pp. 4294-307.Publisher: Bentham Science Publishers Country of Publication: United Arab Emirates NLM ID: 9602487 Publication Model: Print Cited Medium: Internet

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Cytotoxic potency of small macrocyclic knot proteins: structure-activity and mechanistic studies of native and chemically modified cyclotides.

• Authors : Burman R; Division of Pharmacognosy, Department of Medicinal Chemistry, Uppsala University, BMC, Box 574, SE-751 23, Uppsala, Sweden.; Herrmann A

Subjects: Antineoplastic Agents/Antineoplastic Agents/Antineoplastic Agents/*pharmacology ; Cyclotides/Cyclotides/Cyclotides/*pharmacology ; Macrocyclic Compounds/Macrocyclic Compounds/Macrocyclic Compounds/*pharmacology

• Source: Organic & biomolecular chemistry [Org Biomol Chem] 2011 Jun 07; Vol. 9 (11), pp. 4306-14. Date of Electronic Publication: 2011 Apr 13.Publisher: Royal Society of Chemistry Country of Publication: England NLM ID: 101154995 Publication Model: Print-Electronic Cited Medium: Internet

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Anticancer and chemosensitizing abilities of cycloviolacin 02 from Viola odorata and psyle cyclotides from Psychotria leptothyrsa.

• Authors : Gerlach SL; Department of Ecology and Evolutionary Biology, Tulane University, 2863 St. Charles Avenue, 400 Boggs Center for Energy and Biotechnology, New Orleans, LA 70118, USA. ; Rathinakumar R

Subjects: Antineoplastic Agents/Antineoplastic Agents/Antineoplastic Agents/*pharmacology ; Cell Line, Tumor/Cell Line, Tumor/Cell Line, Tumor/*drug effects ; Cyclotides/Cyclotides/Cyclotides/*pharmacology

• Source: Biopolymers [Biopolymers] 2010; Vol. 94 (5), pp. 617-25.Publisher: Wiley Country of Publication: United States NLM ID: 0372525 Publication Model: Print Cited Medium: Print ISSN: 0006-3525 (Print)

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Anticancer and toxic properties of cyclotides are dependent on phosphatidylethanolamine phospholipid targeting.

• Authors : Troeira Henriques S; The University of Queensland, Institute for Molecular Bioscience, Carmody Road, St. Lucia, Brisbane, QLD 4072 (Australia). .; Huang YH

Subjects: Antineoplastic Agents/Antineoplastic Agents/Antineoplastic Agents/*pharmacology ; Antineoplastic Agents/Antineoplastic Agents/Antineoplastic Agents/*toxicity ; Cyclotides/Cyclotides/Cyclotides/*pharmacology

• Source: Chembiochem : a European journal of chemical biology [Chembiochem] 2014 Sep 05; Vol. 15 (13), pp. 1956-65. Date of Electronic Publication: 2014 Aug 05.Publisher: Wiley-VCH Verlag Country of Publication: Germany NLM ID: 100937360 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Potential therapeutic applications of the cyclotides and related cystine knot mini-proteins.

• Authors : Craik DJ; University of Queensland, Institute for Molecular Bioscience, Australian Research Council Special Research Centre for Functional and Applied Genomics, Brisbane QLD 4072, Australia. ; Clark RJ

Subjects: Cystine Knot Motifs* ; Drug Carriers*; Anti-Infective Agents/Anti-Infective Agents/Anti-Infective Agents/*pharmacology

• Source: Expert opinion on investigational drugs [Expert Opin Investig Drugs] 2007 May; Vol. 16 (5), pp. 595-604.Publisher: Taylor & Francis Country of Publication: England NLM ID: 9434197 Publication Model: Print Cited Medium: Internet ISSN: 1744-7658

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In vivo activation of the p53 tumor suppressor pathway by an engineered cyclotide.

• Authors : Ji Y; Department of Pharmacology and Pharmaceutical Sciences, University of Southern California, Los Angeles, CA 90033, USA.; Majumder S

Subjects: Antineoplastic Agents/Antineoplastic Agents/Antineoplastic Agents/*therapeutic use ; Cyclotides/Cyclotides/Cyclotides/*therapeutic use ; Signal Transduction/Signal Transduction/Signal Transduction/*drug effects

• Source: Journal of the American Chemical Society [J Am Chem Soc] 2013 Aug 07; Vol. 135 (31), pp. 11623-11633. Date of Electronic Publication: 2013 Jul 25.Publisher: American Chemical Society Country of Publication: United States NLM ID: 7503056 Publication Model: Print-Electronic Cited Medium: Internet

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Evaluation of toxicity and antitumor activity of cycloviolacin O2 in mice.

• Authors : Burman R; Division of Pharmacognosy, Department of Medicinal Chemistry, Biomedical Centre, Uppsala University, Box 574, SE-751 23 Uppsala, Sweden.; Svedlund E

Subjects: Antineoplastic Agents/Antineoplastic Agents/Antineoplastic Agents/*pharmacology ; Cell Line, Tumor/Cell Line, Tumor/Cell Line, Tumor/*drug effects ; Cyclotides/Cyclotides/Cyclotides/*pharmacology

• Source: Biopolymers [Biopolymers] 2010; Vol. 94 (5), pp. 626-34.Publisher: Wiley Country of Publication: United States NLM ID: 0372525 Publication Model: Print Cited Medium: Print ISSN: 0006-3525 (Print)

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Agricola

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