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Academic Journal

Structure-Based Drug Design of 2-Amino-[1,1'-biphenyl]-3-carboxamide Derivatives as Selective PKMYT1 Inhibitors for the Treatment of CCNE1 -Amplified Breast Cancer.

  • Authors : Wang C; State Key Laboratory of Bioactive Molecules and Druggability Assessment, International Cooperative Laboratory of Traditional Chinese Medicine Modernization and Innovative Drug Discovery of Chinese Ministry of Education, Guangzhou City Key Laboratory of Precision Chemical Drug Development, School of Pharmacy, Jinan University, #855 Xingye Avenue, Guangzhou 510632, China.; Fang Y

Subjects: Breast Neoplasms*/Breast Neoplasms*/Breast Neoplasms*/drug therapy ; Breast Neoplasms*/Breast Neoplasms*/Breast Neoplasms*/pathology ; Drug Design*

  • Source: Journal of medicinal chemistry [J Med Chem] 2024 Sep 12; Vol. 67 (17), pp. 15816-15836. Date of Electronic Publication: 2024 Aug 20.Publisher: American Chemical Society Country of Publication: United States NLM ID: 9716531 Publication Model: Print-Electronic Cited Medium: Internet

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Academic Journal

Icariside II inhibits tumorigenesis via inhibiting AKT/Cyclin E/ CDK 2 pathway and activating mitochondria-dependent pathway.

  • Authors : Sun YS; School of Food and Biological Engineering, Hefei University of Technology, Hefei 230009, PR China. Electronic address: .; Thakur K

Subjects: Antineoplastic Agents/Antineoplastic Agents/Antineoplastic Agents/*pharmacology ; Cyclin E/Cyclin E/Cyclin E/*metabolism ; Cyclin-Dependent Kinase 2/Cyclin-Dependent Kinase 2/Cyclin-Dependent Kinase 2/*metabolism

  • Source: Pharmacological research [Pharmacol Res] 2020 Feb; Vol. 152, pp. 104616. Date of Electronic Publication: 2019 Dec 26.Publisher: Elsevier Country of Publication: Netherlands NLM ID: 8907422 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Phenylpropanoid-based sulfonamide promotes cyclin D1 and cyclin E down-regulation and induces cell cycle arrest at G1/S transition in estrogen positive MCF-7 cell line.

  • Authors : Azevedo-Barbosa H; LQFar - Laboratory of Research in Pharmaceutical Chemistry, Faculty of Pharmaceutical Sciences, Federal University of Alfenas, 37130-001 Alfenas, MG, Brazil.; Ferreira-Silva GÁ

Subjects: Antineoplastic Agents/Antineoplastic Agents/Antineoplastic Agents/*pharmacology ; Cyclin D1/Cyclin D1/Cyclin D1/*metabolism ; Cyclin E/Cyclin E/Cyclin E/*metabolism

  • Source: Toxicology in vitro : an international journal published in association with BIBRA [Toxicol In Vitro] 2019 Sep; Vol. 59, pp. 150-160. Date of Electronic Publication: 2019 Apr 22.Publisher: Pergamon Press Country of Publication: England NLM ID: 8712158 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

LncRNA TTN-AS1 intensifies sorafenib resistance in hepatocellular carcinoma by sponging miR-16-5p and upregulation of cyclin E1.

  • Authors : Zhou Y; Wuxi Second Hospital, Nanjing Medical University, Department of Hepatobiliary Surgery, Wuxi, Jiangsu Province, 214002, PR China.; Huang Y

Subjects: Drug Resistance, Neoplasm*/Drug Resistance, Neoplasm*/Drug Resistance, Neoplasm*/genetics; Antineoplastic Agents/Antineoplastic Agents/Antineoplastic Agents/*pharmacology ; Carcinoma, Hepatocellular/Carcinoma, Hepatocellular/Carcinoma, Hepatocellular/*drug therapy

  • Source: Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie [Biomed Pharmacother] 2021 Jan; Vol. 133, pp. 111030. Date of Electronic Publication: 2020 Nov 28.Publisher: Editions Scientifiques Elsevier Country of Publication: France NLM ID: 8213295 Publication Model: Print-Electronic Cited Medium: Internet

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Academic Journal

CDK4/6 and autophagy inhibitors synergistically induce senescence in Rb positive cytoplasmic cyclin E negative cancers.

  • Authors : Vijayaraghavan S; Department of Experimental Radiation Oncology, The University of Texas MD Anderson Cancer Center, 6565 MD Anderson Boulevard, Houston, Texas 77030, USA.; Graduate School of Biomedical Sciences, The University of Texas MD Anderson Cancer Center, 6767 Bertner Avenue, Houston, Texas 77030, USA.

Subjects: Antineoplastic Agents/Antineoplastic Agents/Antineoplastic Agents/*administration & dosage ; Breast Neoplasms/Breast Neoplasms/Breast Neoplasms/*drug therapy ; Breast Neoplasms/Breast Neoplasms/Breast Neoplasms/*physiopathology

  • Source: Nature communications [Nat Commun] 2017 Jun 27; Vol. 8, pp. 15916. Date of Electronic Publication: 2017 Jun 27.Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN:

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Academic Journal

Cyclin E-Mediated Human Proopiomelanocortin Regulation as a Therapeutic Target for Cushing Disease.

  • Authors : Liu NA; Department of Medicine, Cedars-Sinai Medical Center, Los Angeles, California 90048.; Araki T

Subjects: Antineoplastic Agents/Antineoplastic Agents/Antineoplastic Agents/*therapeutic use ; Cyclin E/Cyclin E/Cyclin E/*antagonists & inhibitors ; Molecular Targeted Therapy/Molecular Targeted Therapy/Molecular Targeted Therapy/*methods

  • Source: The Journal of clinical endocrinology and metabolism [J Clin Endocrinol Metab] 2015 Jul; Vol. 100 (7), pp. 2557-64. Date of Electronic Publication: 2015 May 05.Publisher: Oxford University Press Country of Publication: United States NLM ID: 0375362 Publication Model: Print-Electronic Cited Medium: Internet

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Academic Journal

Simvastatin induces G 1 arrest by up-regulating GSK3β and down-regulating CDK4/cyclin D1 and CDK2/cyclin E1 in human primary colorectal cancer cells.

  • Authors : Chen MJ; Department of Surgery, Chi-Mei Medical Center, Tainan, Taiwan.; Department of Sports Management, College of Leisure and Recreation Management, Chia Nan University of Pharmacy and Science, Tainan, Taiwan.

Subjects: Antineoplastic Agents/Antineoplastic Agents/Antineoplastic Agents/*pharmacology ; Colorectal Neoplasms/Colorectal Neoplasms/Colorectal Neoplasms/*drug therapy ; Cyclin D1/Cyclin D1/Cyclin D1/*metabolism

  • Source: Journal of cellular physiology [J Cell Physiol] 2018 Jun; Vol. 233 (6), pp. 4618-4625. Date of Electronic Publication: 2018 Jan 15.Publisher: Wiley-Liss Country of Publication: United States NLM ID: 0050222 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Panobinostat sensitizes cyclin E high, homologous recombination-proficient ovarian cancer to olaparib.

  • Authors : Wilson AJ; Department of Obstetrics & Gynecology, Division of Gynecologic Oncology, Vanderbilt University Medical Center, Nashville, TN, United States.; Sarfo-Kantanka K

Subjects: Homologous Recombination*; Antineoplastic Agents/Antineoplastic Agents/Antineoplastic Agents/*therapeutic use ; Cyclin E/Cyclin E/Cyclin E/*analysis

  • Source: Gynecologic oncology [Gynecol Oncol] 2016 Oct; Vol. 143 (1), pp. 143-151. Date of Electronic Publication: 2016 Jul 19.Publisher: Academic Press Country of Publication: United States NLM ID: 0365304 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

VR23: A Quinoline-Sulfonyl Hybrid Proteasome Inhibitor That Selectively Kills Cancer via Cyclin E-Mediated Centrosome Amplification.

  • Authors : Pundir S; Advanced Medical Research Institute of Canada, Sudbury, Ontario, Canada. Department of Biochemistry, Microbiology and Immunology, Faculty of Medicine, University of Ottawa, Ottawa, Ontario, Canada.; Vu HY

Subjects: Molecular Targeted Therapy*; Antineoplastic Agents/Antineoplastic Agents/Antineoplastic Agents/*pharmacology ; Antineoplastic Combined Chemotherapy Protocols/Antineoplastic Combined Chemotherapy Protocols/Antineoplastic Combined Chemotherapy Protocols/*therapeutic use

  • Source: Cancer research [Cancer Res] 2015 Oct 01; Vol. 75 (19), pp. 4164-75. Date of Electronic Publication: 2015 Aug 03.Publisher: American Association for Cancer Research Country of Publication: United States NLM ID: 2984705R Publication Model: Print-Electronic Cited Medium:

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Academic Journal

Cyclin E transgenic mice: discovery tools for lung cancer biology, therapy, and prevention.

  • Authors : Freemantle SJ; Department of Pharmacology and Toxicology, Dartmouth Medical School, Hanover, NH 03755, USA. ; Dmitrovsky E

Subjects: Disease Models, Animal*; Adenocarcinoma/Adenocarcinoma/Adenocarcinoma/*prevention & control ; Antineoplastic Agents/Antineoplastic Agents/Antineoplastic Agents/*therapeutic use

  • Source: Cancer prevention research (Philadelphia, Pa.) [Cancer Prev Res (Phila)] 2010 Dec; Vol. 3 (12), pp. 1513-8.Publisher: American Association for Cancer Research Country of Publication: United States NLM ID: 101479409 Publication Model: Print Cited Medium:

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  • 1-10 of  1,537 results for ""Cyclin E""