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Academic Journal

Pd-Catalyzed Coupling of Bromo-N- (β-glucopyranosyl)quinolin-2-ones with Amides: Synthesis of N-glucosyl-6BrCaQ Conjugates with Potent Anticancer Activity.

  • Authors : Redjdal W; Université de Bejaia, Faculté des Sciences Exactes, Laboratoire de Physico-Chimie des Matériaux et Catalyse, 06000, Bejaia, Algeria.; Benmahdjoub S

Subjects: Antineoplastic Agents*/Antineoplastic Agents*/Antineoplastic Agents*/pharmacology ; Antineoplastic Agents*/Antineoplastic Agents*/Antineoplastic Agents*/chemistry ; Antineoplastic Agents*/Antineoplastic Agents*/Antineoplastic Agents*/chemical synthesis

  • Source: ChemMedChem [ChemMedChem] 2024 Aug 01; Vol. 19 (15), pp. e202400195. Date of Electronic Publication: 2024 Jun 15.Publisher: Wiley-VCH Country of Publication: Germany NLM ID: 101259013 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1860-7187

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Academic Journal

Semi-synthesis of phenolic-amides and their cytotoxicity against THP-1, HeLa, HepG2 and MCF-7 cell lines.

  • Authors : Gorantla JN; Center for Biomolecular Structure, Function and Application, Suranaree University of Technology, Nakhon Ratchasima, Thailand.; School of Chemistry, Institute of Science, Suranaree University of Technology, Nakhon Ratchasima, Thailand.

Subjects: Amides*/Amides*/Amides*/chemistry ; Amides*/Amides*/Amides*/pharmacology ; Phenols*/Phenols*/Phenols*/chemistry

  • Source: Natural product research [Nat Prod Res] 2024 Jun; Vol. 38 (12), pp. 2069-2077. Date of Electronic Publication: 2023 Aug 01.Publisher: Taylor & Francis Health Sciences Country of Publication: England NLM ID: 101167924 Publication Model: Print-Electronic Cited Medium: Internet

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Academic Journal

Structural insights and cytotoxicity evaluation of benz[e]indole pyrazolyl-substituted amides.

  • Authors : Ramle AQ; School of Chemical Sciences, Universiti Sains Malaysia, 11800, Penang, Malaysia. .; Chan NNMY

Subjects: Amides*/Amides*/Amides*/chemistry ; Antineoplastic Agents*/Antineoplastic Agents*/Antineoplastic Agents*/pharmacology ; Antineoplastic Agents*/Antineoplastic Agents*/Antineoplastic Agents*/chemistry

  • Source: Molecular diversity [Mol Divers] 2024 Jun; Vol. 28 (3), pp. 1363-1376. Date of Electronic Publication: 2023 Jun 06.Publisher: ESCOM Science Publishers Country of Publication: Netherlands NLM ID: 9516534 Publication Model: Print-Electronic Cited Medium: Internet

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Academic Journal

Synthesis, DFT Calculations, and Biological Studies of New 2-Cyano-3-(Naphthalene-1-yl) Acryloyl Amide Analogues as Anticancer Agents.

  • Authors : Hekal MH; Chemistry Department, Faculty of Science, Ain Shams University, 11566, Cairo, Egypt.; Abdalha AA

Subjects: Antineoplastic Agents*/Antineoplastic Agents*/Antineoplastic Agents*/pharmacology ; Antineoplastic Agents*/Antineoplastic Agents*/Antineoplastic Agents*/chemical synthesis ; Antineoplastic Agents*/Antineoplastic Agents*/Antineoplastic Agents*/chemistry

  • Source: Chemistry & biodiversity [Chem Biodivers] 2024 Oct; Vol. 21 (10), pp. e202401023. Date of Electronic Publication: 2024 Sep 09.Publisher: Verlag Helvetica Chimica Acta Country of Publication: Switzerland NLM ID: 101197449 Publication Model: Print-Electronic Cited Medium:

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Academic Journal

Synthesis of 2-phenylnaphthalenoid amide derivatives and their topoisomerase IIα inhibitory and antiproliferative activities.

  • Authors : Wu X; Department of Natural Pharmaceutical Chemistry, Key Laboratory of Chemical Biology (Ministry of Education), School of Pharmaceutical Sciences, Shandong University, Jinan, China.; Xu G

Subjects: Amides*/Amides*/Amides*/pharmacology ; Amides*/Amides*/Amides*/chemical synthesis ; Amides*/Amides*/Amides*/chemistry

  • Source: Archiv der Pharmazie [Arch Pharm (Weinheim)] 2024 Oct; Vol. 357 (10), pp. e2400175. Date of Electronic Publication: 2024 Jun 23.Publisher: Wiley-VCH Verlag GmbH & Co. KGaA Country of Publication: Germany NLM ID: 0330167 Publication Model: Print-Electronic Cited Medium: Internet

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Academic Journal

Design, synthesis and biological evaluation of naphthyl amide derivatives as reversible monoacylglycerol lipase (MAGL) inhibitors.

  • Authors : Yu Q; Department of Respiratory and Critical Care Medicine, Targeted Tracer Research and Development Laboratory, West China Hospital, Sichuan University, Chengdu, Sichuan, China; Institute of Respiratory Health, Targeted Tracer Research and Development Laboratory, Frontiers Science Center for Disease-related Molecular Network, West China Hospital, Sichuan University, Chengdu, Sichuan, China.

Subjects: Monoacylglycerol Lipases*/Monoacylglycerol Lipases*/Monoacylglycerol Lipases*/antagonists & inhibitors ; Monoacylglycerol Lipases*/Monoacylglycerol Lipases*/Monoacylglycerol Lipases*/metabolism ; Drug Design*

  • Source: Bioorganic & medicinal chemistry [Bioorg Med Chem] 2024 Sep 01; Vol. 111, pp. 117844. Date of Electronic Publication: 2024 Jul 23.Publisher: Elsevier Science Country of Publication: England NLM ID: 9413298 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Structure-Activity Relationship Studies on Highly Functionalized Pyrazole Hydrazones and Amides as Antiproliferative and Antioxidant Agents.

  • Authors : Lusardi M; Department of Pharmacy, University of Genova, Viale Benedetto XV, 3, 16132 Genova, Italy.; Signorello MG

Subjects: Pyrazoles*/Pyrazoles*/Pyrazoles*/chemistry ; Pyrazoles*/Pyrazoles*/Pyrazoles*/pharmacology ; Hydrazones*/Hydrazones*/Hydrazones*/chemistry

  • Source: International journal of molecular sciences [Int J Mol Sci] 2024 Apr 23; Vol. 25 (9). Date of Electronic Publication: 2024 Apr 23.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067

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Academic Journal

Synthesis, Pharmacokinetic Profile, Anticancer Activity and Toxicity of the New Amides of Betulonic Acid-In Silico and In Vitro Study.

  • Authors : Bębenek E; Department of Organic Chemistry, Faculty of Pharmaceutical Sciences in Sosnowiec, Medical University of Silesia in Katowice, 4 Jagiellońska, 41-200 Sosnowiec, Poland.; Rzepka Z

Subjects: Amides*/Amides*/Amides*/chemistry ; Amides*/Amides*/Amides*/pharmacology ; Antineoplastic Agents*/Antineoplastic Agents*/Antineoplastic Agents*/pharmacology

  • Source: International journal of molecular sciences [Int J Mol Sci] 2024 Apr 20; Vol. 25 (8). Date of Electronic Publication: 2024 Apr 20.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067

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Academic Journal

Design, Synthesis and Antitumor Activity of a Novel Class of SHP2 Allosteric Inhibitors with a Furanyl Amide-Based Scaffold.

  • Authors : Zhu C; School of Pharmaceutical Sciences, Cheeloo College of Medicine, Shandong University, Jinan 250012, P.R. China.; Zhao H

Subjects: Protein Tyrosine Phosphatase, Non-Receptor Type 11*/Protein Tyrosine Phosphatase, Non-Receptor Type 11*/Protein Tyrosine Phosphatase, Non-Receptor Type 11*/antagonists & inhibitors ; Protein Tyrosine Phosphatase, Non-Receptor Type 11*/Protein Tyrosine Phosphatase, Non-Receptor Type 11*/Protein Tyrosine Phosphatase, Non-Receptor Type 11*/metabolism ; Drug Design*

  • Source: Journal of medicinal chemistry [J Med Chem] 2024 Aug 08; Vol. 67 (15), pp. 13305-13323. Date of Electronic Publication: 2024 Jul 27.Publisher: American Chemical Society Country of Publication: United States NLM ID: 9716531 Publication Model: Print-Electronic Cited Medium: Internet

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Academic Journal

Design, concise synthesis and evaluation of novel amide-based combretastatin A-4 analogues as potent tubulin inhibitors.

  • Authors : Ma Y; Guangdong Provincial Key Laboratory of New Drug Screening, School of Pharmaceutical Science, Southern Medical University, Guangzhou 510515, PR China.; Wang T

Subjects: Tubulin Modulators*/Tubulin Modulators*/Tubulin Modulators*/pharmacology ; Tubulin Modulators*/Tubulin Modulators*/Tubulin Modulators*/chemical synthesis ; Tubulin Modulators*/Tubulin Modulators*/Tubulin Modulators*/chemistry

  • Source: Bioorganic & medicinal chemistry letters [Bioorg Med Chem Lett] 2024 Aug 01; Vol. 108, pp. 129816. Date of Electronic Publication: 2024 May 26.Publisher: Elsevier Science Ltd Country of Publication: England NLM ID: 9107377 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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