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Academic Journal

Is hypoalbuminemia a risk factor for high-dose methotrexate toxicity in children with acute lymphoblastic leukemia?

  • Authors : Barakat S; Department of Pediatrics, General Organization for Teaching Hospitals and Institutes, Cairo, Egypt. .; Assem H

Subjects: Antimetabolites, Antineoplastic*/Antimetabolites, Antineoplastic*/Antimetabolites, Antineoplastic*/adverse effects ; Antimetabolites, Antineoplastic*/Antimetabolites, Antineoplastic*/Antimetabolites, Antineoplastic*/therapeutic use ; Hypoalbuminemia*/Hypoalbuminemia*/Hypoalbuminemia*/therapy

  • Source: Journal of the Egyptian National Cancer Institute [J Egypt Natl Canc Inst] 2022 Apr 18; Vol. 34 (1), pp. 17. Date of Electronic Publication: 2022 Apr 18.Publisher: SpringerOpen Country of Publication: England NLM ID: 9424566 Publication Model: Electronic Cited Medium: Internet ISSN: 2589-0409

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New Therapeutic Approach to Reduce Methotrexate Toxicity after High-Dose Chemotherapy in a Child with Acute Lymphocytic Leukemia: Efficacy and Safety of Hemoadsorption with HA-230 Adsorber.

  • Authors : Sazonov V; Pediatric Anesthesiology and Intensive care Unit, 'University Medical Center' National Research Center for Maternal and Child Health, Nur-Sultan, Kazakhstan, .; Department of Biomedical Sciences, Nazarbayev University School of Medicine, Nur-Sultan, Kazakhstan, .

Subjects: Hemoperfusion*/Hemoperfusion*/Hemoperfusion*/methods; Antimetabolites, Antineoplastic/Antimetabolites, Antineoplastic/Antimetabolites, Antineoplastic/*isolation & purification ; Antimetabolites, Antineoplastic/Antimetabolites, Antineoplastic/Antimetabolites, Antineoplastic/*toxicity

  • Source: Blood purification [Blood Purif] 2022; Vol. 51 (1), pp. 91-95. Date of Electronic Publication: 2021 Mar 16.Publisher: S. Karger Country of Publication: Switzerland NLM ID: 8402040 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Cutaneous ulceration: A sign of methotrexate toxicity in oral cancer patient.

  • Authors : Kumar N; Department of Surgical Oncology, All India Institute of Medical Sciences, New Delhi, India. Electronic address: .; Bhoriwal S

Subjects: Antimetabolites, Antineoplastic/Antimetabolites, Antineoplastic/Antimetabolites, Antineoplastic/*adverse effects ; Methotrexate/Methotrexate/Methotrexate/*adverse effects ; Mouth Neoplasms/Mouth Neoplasms/Mouth Neoplasms/*complications

  • Source: Oral oncology [Oral Oncol] 2020 Oct; Vol. 109, pp. 104671. Date of Electronic Publication: 2020 Apr 06.Publisher: Elsevier Country of Publication: England NLM ID: 9709118 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1879-0593

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Academic Journal

Endogenous Metabolites-Mediated Communication Between OAT1/OAT3 and OATP1B1 May Explain the Association Between SLCO1B1 SNPs and Methotrexate Toxicity.

  • Authors : Martinez D; CHU Tours, Laboratory of Biochemistry and Molecular Biology, Tours, France.; Muhrez K

Subjects: Pharmacogenomic Variants* ; Polymorphism, Single Nucleotide*; Antimetabolites, Antineoplastic/Antimetabolites, Antineoplastic/Antimetabolites, Antineoplastic/*adverse effects

  • Source: Clinical pharmacology and therapeutics [Clin Pharmacol Ther] 2018 Oct; Vol. 104 (4), pp. 687-698. Date of Electronic Publication: 2018 Jan 31.Publisher: Wiley Country of Publication: United States NLM ID: 0372741 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1532-6535

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Academic Journal

Use of MTHFR C677T polymorphism and plasma pharmacokinetics to predict methotrexate toxicity in patients with acute lymphoblastic leukemia.

  • Authors : Mahmoud LB; Department of Pharmacology, Faculty of Medicine, University of Sfax, Tunisia.; Mdhaffar M

Subjects: Antimetabolites, Antineoplastic/Antimetabolites, Antineoplastic/Antimetabolites, Antineoplastic/*adverse effects ; Methotrexate/Methotrexate/Methotrexate/*adverse effects ; Methylenetetrahydrofolate Reductase (NADPH2)/Methylenetetrahydrofolate Reductase (NADPH2)/Methylenetetrahydrofolate Reductase (NADPH2)/*genetics

  • Source: Advances in clinical and experimental medicine : official organ Wroclaw Medical University [Adv Clin Exp Med] 2018 Aug; Vol. 27 (8), pp. 1061-1068.Publisher: The University Country of Publication: Poland NLM ID: 101138582 Publication Model: Print Cited Medium: Print ISSN: 1899-5276 (Print)

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Acute methotrexate toxicity presenting with bullous lesions: an unusual presentation.

  • Authors : Sanke S; Department of Dermatology and Sexually Transmitted Diseases and Department of Pediatrics, Lady Hardinge Medical College and associated hospitals, Shaheed Bhagat Singh Marg, New Delhi, 110001, India. .; Yadav P

Subjects: Antimetabolites, Antineoplastic/Antimetabolites, Antineoplastic/Antimetabolites, Antineoplastic/*adverse effects ; Blister/Blister/Blister/*chemically induced ; Methotrexate/Methotrexate/Methotrexate/*adverse effects

  • Source: European journal of clinical pharmacology [Eur J Clin Pharmacol] 2017 Apr; Vol. 73 (4), pp. 515-516. Date of Electronic Publication: 2016 Dec 14.Publisher: Springer Country of Publication: Germany NLM ID: 1256165 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1432-1041

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Academic Journal

MTHFR gene polymorphisms and methotrexate toxicity in adult patients with hematological malignancies: a meta-analysis.

  • Authors : Zhao M; Department of Pharmacy, Beijing Hospital, No. 1 Dahua Road, Dong Dan, Beijing 100730, P. R. China.; Liang L

Subjects: Antimetabolites, Antineoplastic/Antimetabolites, Antineoplastic/Antimetabolites, Antineoplastic/*adverse effects ; Antimetabolites, Antineoplastic/Antimetabolites, Antineoplastic/Antimetabolites, Antineoplastic/*therapeutic use ; Hematologic Neoplasms/Hematologic Neoplasms/Hematologic Neoplasms/*complications

  • Source: Pharmacogenomics [Pharmacogenomics] 2016 Jun; Vol. 17 (9), pp. 1005-17. Date of Electronic Publication: 2016 Jun 08.Publisher: Future Medicine Ltd Country of Publication: England NLM ID: 100897350 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Systematic review: genetic polymorphisms in the pharmacokinetics of high-dose methotrexate in pediatric acute lymphoblastic leukemia patients.

  • Authors : Rahmayanti SU; Master Program in Pharmacy, Faculty of Pharmacy, Padjadjaran University, Sumedang, West Java, 45363, Indonesia.; Amalia R

Subjects: Antimetabolites, Antineoplastic*/Antimetabolites, Antineoplastic*/Antimetabolites, Antineoplastic*/administration & dosage ; Antimetabolites, Antineoplastic*/Antimetabolites, Antineoplastic*/Antimetabolites, Antineoplastic*/pharmacokinetics ; Methotrexate*/Methotrexate*/Methotrexate*/administration & dosage

  • Source: Cancer chemotherapy and pharmacology [Cancer Chemother Pharmacol] 2024 Aug; Vol. 94 (2), pp. 141-155. Date of Electronic Publication: 2024 Jul 13.Publisher: Springer Verlag Country of Publication: Germany NLM ID: 7806519 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Effect of polymorphisms within methotrexate pathway genes on methotrexate toxicity and plasma levels in adults with hematological malignancies.

  • Authors : Suthandiram S; The Pharmacogenomics Laboratory, Department of Pharmacology, University of Malaya, Kuala Lumpur, Malaysia.; Gan GG

Subjects: Antimetabolites, Antineoplastic/Antimetabolites, Antineoplastic/Antimetabolites, Antineoplastic/*adverse effects ; Antimetabolites, Antineoplastic/Antimetabolites, Antineoplastic/Antimetabolites, Antineoplastic/*therapeutic use ; Hematologic Neoplasms/Hematologic Neoplasms/Hematologic Neoplasms/*drug therapy

  • Source: Pharmacogenomics [Pharmacogenomics] 2014 Aug; Vol. 15 (11), pp. 1479-94.Publisher: Future Medicine Ltd Country of Publication: England NLM ID: 100897350 Publication Model: Print Cited Medium: Internet ISSN: 1744-8042

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Academic Journal

High-dose methotrexate in adult oncology patients: a case-control study assessing the risk association between drug interactions and methotrexate toxicity.

  • Authors : Chan AJ; Department of Pharmacy, London Health Sciences Centre, London, Ontario, Canada.; Rajakumar I

Subjects: Drug Interactions*; Antimetabolites, Antineoplastic/Antimetabolites, Antineoplastic/Antimetabolites, Antineoplastic/*administration & dosage ; Antimetabolites, Antineoplastic/Antimetabolites, Antineoplastic/Antimetabolites, Antineoplastic/*adverse effects

  • Source: Journal of oncology pharmacy practice : official publication of the International Society of Oncology Pharmacy Practitioners [J Oncol Pharm Pract] 2014 Apr; Vol. 20 (2), pp. 93-9. DatePublisher: SAGE Publications Country of Publication: England NLM ID: 9511372 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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  • 1-10 of  61 results for ""Methotrexate toxicity""