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Academic Journal

Surface modification of pralidoxime chloride-loaded solid lipid nanoparticles for enhanced brain reactivation of organophosphorus-inhibited AChE: Pharmacokinetics in rat.

  • Authors : Buzyurova DN; Arbuzov Institute of Organic and Physical Chemistry, FRC Kazan Scientific Center of RAS, Arbuzov St., 8, Kazan, 420088, Russia.; Pashirova TN

Subjects: Antidotes/Antidotes/Antidotes/*administration & dosage ; Cholinesterase Inhibitors/Cholinesterase Inhibitors/Cholinesterase Inhibitors/*toxicity ; Cholinesterase Reactivators/Cholinesterase Reactivators/Cholinesterase Reactivators/*administration & dosage

  • Source: Toxicology [Toxicology] 2020 Nov; Vol. 444, pp. 152578. Date of Electronic Publication: 2020 Sep 06.Publisher: Elsevier Country of Publication: Ireland NLM ID: 0361055 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1879-3185

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Academic Journal

Pralidoxime administered during cardiopulmonary resuscitation facilitates successful resuscitation in a pig model of cardiac arrest.

  • Authors : Jung YH; Department of Emergency Medicine, Chonnam National University Hospital, Gwangju, Korea.; Department of Emergency Medicine, Chonnam National University Medical School, Gwangju, Korea.

Subjects: Disease Models, Animal*; Antidotes/Antidotes/Antidotes/*therapeutic use ; Cardiopulmonary Resuscitation/Cardiopulmonary Resuscitation/Cardiopulmonary Resuscitation/*methods

  • Source: Clinical and experimental pharmacology & physiology [Clin Exp Pharmacol Physiol] 2020 Feb; Vol. 47 (2), pp. 236-246. Date of Electronic Publication: 2019 Nov 17.Publisher: Wiley-Blackwell Country of Publication: Australia NLM ID: 0425076 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Organophosphorus Compounds Poisoning in a Neonate: A Case Report.

  • Authors : Das JC; Professor Jagadish C Das, Professor, Department of Neonatology, Chittagong Medical College (CMC), Chittagong, Bangladesh; E-mail: .

Subjects: Antidotes/Antidotes/Antidotes/*administration & dosage ; Atropine/Atropine/Atropine/*administration & dosage ; Insecticides/Insecticides/Insecticides/*poisoning

  • Source: Mymensingh medical journal : MMJ [Mymensingh Med J] 2019 Apr; Vol. 28 (2), pp. 470-473.Publisher: Mymensingh Medical College Country of Publication: Bangladesh NLM ID: 9601799 Publication Model: Print Cited Medium: Internet ISSN:

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Academic Journal

In silico and in vitro evaluation of two novel oximes (K378 and K727) in comparison to K-27 and pralidoxime against paraoxon-ethyl intoxication.

  • Authors : Arshad M; a Department of Biosciences , COMSATS Institute of Information Technology , Islamabad , Pakistan.; Fatmi MQ

Subjects: Molecular Docking Simulation*; Antidotes/Antidotes/Antidotes/*pharmacology ; Cholinesterase Inhibitors/Cholinesterase Inhibitors/Cholinesterase Inhibitors/*toxicity

  • Source: Toxicology mechanisms and methods [Toxicol Mech Methods] 2018 Jan; Vol. 28 (1), pp. 62-68. Date of Electronic Publication: 2017 Aug 04.Publisher: Informa Healthcare Country of Publication: England NLM ID: 101134521 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Radiosynthesis, ex Vivo Biodistribution, and in Vivo Positron Emission Tomography Imaging Evaluations of [ 11 C]2-Pyridinealdoxime Methiodide ([ 11 C]2-PAM): A First-In-Class Antidote Tracer for Organophosphate Intoxication.

  • Authors : Neumann KD; Department of Radiology and Biomedical Imaging , University of California, San Francisco , San Francisco , California 94143 , United States.; Blecha JE

Subjects: Organophosphate Poisoning*; Antidotes/Antidotes/Antidotes/*pharmacokinetics ; Carbon Radioisotopes/Carbon Radioisotopes/Carbon Radioisotopes/*pharmacokinetics

  • Source: ACS chemical neuroscience [ACS Chem Neurosci] 2018 Dec 19; Vol. 9 (12), pp. 3007-3014. Date of Electronic Publication: 2018 Aug 20.Publisher: American Chemical Society Country of Publication: United States NLM ID: 101525337 Publication Model: Print-Electronic Cited Medium: Internet

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Academic Journal

Novel pyridinium oximes enhance 24-h survivability against a lethal dose of nerve agent surrogate in adult female rats.

  • Authors : Garcia JM; Center for Environmental Health Sciences, Department of Basic Sciences, College of Veterinary Medicine, Mississippi State University, P.O. Box 6100, Mississippi State, MS, 39762, USA. Electronic address: .; Meek EC

Subjects: Antidotes/Antidotes/Antidotes/*pharmacology ; Cholinesterase Inhibitors/Cholinesterase Inhibitors/Cholinesterase Inhibitors/*toxicity ; Nerve Agents/Nerve Agents/Nerve Agents/*toxicity

  • Source: Toxicology [Toxicology] 2020 Dec 15; Vol. 446, pp. 152626. Date of Electronic Publication: 2020 Nov 04.Publisher: Elsevier Country of Publication: Ireland NLM ID: 0361055 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1879-3185

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Academic Journal

Central neuroprotection demonstrated by novel oxime countermeasures to nerve agent surrogates.

  • Authors : Chambers JE; Center for Environmental Health Sciences, College of Veterinary Medicine, Mississippi State University, Mississippi State, Mississippi.; Meek EC

Subjects: Antidotes/Antidotes/Antidotes/*therapeutic use ; Nerve Agents/Nerve Agents/Nerve Agents/*toxicity ; Neuroprotection/Neuroprotection/Neuroprotection/*drug effects

  • Source: Annals of the New York Academy of Sciences [Ann N Y Acad Sci] 2020 Nov; Vol. 1479 (1), pp. 5-12. Date of Electronic Publication: 2020 Apr 21.Publisher: New York Academy of Sciences Country of Publication: United States NLM ID: 7506858 Publication Model: Print-Electronic Cited Medium: Internet

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Academic Journal

The antidotes atropine and pralidoxime distinctively recover cardiorespiratory components impaired by acute poisoning with chlorpyrifos in rats.

  • Authors : Felippe ISA; Postgraduate Program in Pharmaceutical Sciences, Department of Pharmaceutical Sciences, Federal University of Espírito Santo, Vitória, ES, Brazil; Department of Physiology, Faculty of Health & Medical Sciences, University of Auckland, Grafton Campus, Auckland 1023, New Zealand.

Subjects: Antidotes/Antidotes/Antidotes/*pharmacology ; Atropine/Atropine/Atropine/*pharmacology ; Cardiovascular System/Cardiovascular System/Cardiovascular System/*drug effects

  • Source: Toxicology and applied pharmacology [Toxicol Appl Pharmacol] 2020 Jan 15; Vol. 389, pp. 114879. Date of Electronic Publication: 2020 Jan 10.Publisher: Academic Press Country of Publication: United States NLM ID: 0416575 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Pralidoxime.

Subjects: Antidotes/Antidotes/Antidotes/*pharmacology ; Pralidoxime Compounds/Pralidoxime Compounds/Pralidoxime Compounds/*pharmacology; Antidotes/Antidotes/Antidotes/adverse effects

  • Source: Chudoku kenkyu : Chudoku Kenkyukai jun kikanshi = The Japanese journal of toxicology [Chudoku Kenkyu] 2016 Dec; Vol. 29 (4), pp. 371-377.Publisher: Yakugyō Jihōsha Country of Publication: Japan NLM ID: 9310053 Publication Model: Print Cited Medium: Print ISSN: 0914-3777 (Print)

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Academic Journal

Efficacy of Recommended Prehospital Human Equivalent Doses of Atropine and Pralidoxime Against the Toxic Effects of Carbamate Poisoning in the Hartley Guinea Pig.

Subjects: Antidotes/Antidotes/Antidotes/*administration & dosage ; Atropine/Atropine/Atropine/*administration & dosage ; Cholinesterase Reactivators/Cholinesterase Reactivators/Cholinesterase Reactivators/*administration & dosage

  • Source: International journal of toxicology [Int J Toxicol] 2016 May; Vol. 35 (3), pp. 344-57. Date of Electronic Publication: 2016 Apr 21.Publisher: Sage Publications Country of Publication: United States NLM ID: 9708436 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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  • 1-10 of  218 results for ""Pralidoxime Compounds""