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Academic Journal

Amphetamine Derivatives as Potent Central Nervous System Multitarget SERT/NET/H 3 Agents: Synthesis and Biological Evaluation.

  • Authors : Li Q; School of Pharmacy, Nanjing Tech University, 30th South Puzhu Road, Nanjing 211816, China.; Ren L

Subjects: Molecular Docking Simulation* ; Serotonin Plasma Membrane Transport Proteins*/Serotonin Plasma Membrane Transport Proteins*/Serotonin Plasma Membrane Transport Proteins*/metabolism ; Receptors, Histamine H3*/Receptors, Histamine H3*/Receptors, Histamine H3*/metabolism

  • Source: Molecules (Basel, Switzerland) [Molecules] 2024 Nov 06; Vol. 29 (22). Date of Electronic Publication: 2024 Nov 06.Publisher: MDPI Country of Publication: Switzerland NLM ID: 100964009 Publication Model: Electronic Cited Medium: Internet ISSN: 1420-3049

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Academic Journal

Design and Synthesis of Potential Multi-Target Antidepressants: Exploration of 1-(4-(7-Azaindole)-3,6-dihydropyridin-1-yl)alkyl-3-(1 H -indol-3-yl)pyrrolidine-2,5-dione Derivatives with Affinity for the Serotonin Transporter.

  • Authors : Wróbel MZ; Department of Drug Technology and Pharmaceutical Biotechnology, Faculty of Pharmacy, Medical University of Warsaw, 1 Banacha Street, 02-097 Warszawa, Poland.; Chodkowski A

Subjects: Serotonin Plasma Membrane Transport Proteins*/Serotonin Plasma Membrane Transport Proteins*/Serotonin Plasma Membrane Transport Proteins*/metabolism ; Antidepressive Agents*/Antidepressive Agents*/Antidepressive Agents*/pharmacology ; Antidepressive Agents*/Antidepressive Agents*/Antidepressive Agents*/chemistry

  • Source: International journal of molecular sciences [Int J Mol Sci] 2024 Oct 20; Vol. 25 (20). Date of Electronic Publication: 2024 Oct 20.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067

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Dual 5-HT 6 /SERT ligands for mitigating neuropsychiatric symptoms of dementia exerting neuroprotection against amyloid-β toxicity, memory preservation, and antidepressant-like properties.

  • Authors : Siwek A; Jagiellonian University Medical College, Faculty of Pharmacy, 9 Medyczna St., 30-688, Krakow, Poland. Electronic address: .; Marcinkowska M

Subjects: Amyloid beta-Peptides*/Amyloid beta-Peptides*/Amyloid beta-Peptides*/metabolism ; Amyloid beta-Peptides*/Amyloid beta-Peptides*/Amyloid beta-Peptides*/antagonists & inhibitors ; Antidepressive Agents*/Antidepressive Agents*/Antidepressive Agents*/pharmacology

  • Source: European journal of medicinal chemistry [Eur J Med Chem] 2024 Sep 05; Vol. 275, pp. 116601. Date of Electronic Publication: 2024 Jun 14.Publisher: Editions Scientifiques Elsevier Country of Publication: France NLM ID: 0420510 Publication Model: Print-Electronic Cited Medium: Internet

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Academic Journal

Development of Nitric Oxide Releasing Oxoisoaporphines with Antidepressant Activities by Simultaneously Regulating MAO-A and SERT.

  • Authors : Zhong P; State Key Laboratory of Natural Medicines, Department of Natural Medicinal Chemistry, School of Traditional Chinese Pharmacy, China Pharmaceutical University, 639 Longmian Avenue, Nanjing 211198, China.; Mao X

Subjects: Antidepressive Agents*/Antidepressive Agents*/Antidepressive Agents*/pharmacology ; Antidepressive Agents*/Antidepressive Agents*/Antidepressive Agents*/chemistry ; Antidepressive Agents*/Antidepressive Agents*/Antidepressive Agents*/chemical synthesis

  • Source: Journal of medicinal chemistry [J Med Chem] 2024 Sep 12; Vol. 67 (17), pp. 15509-15520. Date of Electronic Publication: 2024 Aug 27.Publisher: American Chemical Society Country of Publication: United States NLM ID: 9716531 Publication Model: Print-Electronic Cited Medium: Internet

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Etanercept ameliorates chronic mild stress-induced depressive-like behavior in rats: Crosstalk between MAPK and STAT3 pathways and norepinephrine and serotonin transporters.

  • Authors : Fouad MA; Laboratory Evaluation Administration, CA of Biological and Innovative Products and Clinical Studies, Egyptian Drug Authority, Giza, Egypt.; Tadros MG

Subjects: Etanercept*/Etanercept*/Etanercept*/pharmacology ; Etanercept*/Etanercept*/Etanercept*/therapeutic use ; Rats, Wistar*

  • Source: European journal of pharmacology [Eur J Pharmacol] 2024 Sep 05; Vol. 978, pp. 176801. Date of Electronic Publication: 2024 Jun 28.Publisher: Elsevier Science Country of Publication: Netherlands NLM ID: 1254354 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Allosteric Inhibition and Pharmacochaperoning of the Serotonin Transporter by the Antidepressant Drugs Trazodone and Nefazodone.

  • Authors : El-Kasaby A; Institute of Pharmacology and the Gaston H. Glock Research Laboratories for Exploratory Drug Development, Centre of Physiology and Pharmacology (A.E.-K., D.B., M.F., W.S.), Medical University of Vienna, Vienna, Austria; Department of Neurobiology, University of Vienna, Vienna, Austria (A.K., T.H.)

Subjects: Serotonin Plasma Membrane Transport Proteins*/Serotonin Plasma Membrane Transport Proteins*/Serotonin Plasma Membrane Transport Proteins*/metabolism ; Serotonin Plasma Membrane Transport Proteins*/Serotonin Plasma Membrane Transport Proteins*/Serotonin Plasma Membrane Transport Proteins*/genetics ; Trazodone*/Trazodone*/Trazodone*/pharmacology

  • Source: Molecular pharmacology [Mol Pharmacol] 2024 Jun 18; Vol. 106 (1), pp. 56-70. Date of Electronic Publication: 2024 Jun 18.Publisher: American Society for Pharmacology and Experimental Therapeutics Country of Publication: United States NLM ID: 0035623 Publication Model: Electronic

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DSP-6745, a novel 5-hydroxytryptamine modulator with rapid antidepressant, anxiolytic, antipsychotic and procognitive effects.

  • Authors : Kitaichi M; Drug Research Division, Sumitomo Pharma Co., Ltd., Osaka, 554-0022, Japan.; Laboratory of Molecular Pharmacology, Institute of Medical, Pharmaceutical and Health Sciences, Kanazawa University, Kanazawa, 920-1192, Japan.

Subjects: Antidepressive Agents*/Antidepressive Agents*/Antidepressive Agents*/pharmacology ; Antidepressive Agents*/Antidepressive Agents*/Antidepressive Agents*/administration & dosage ; Antipsychotic Agents*/Antipsychotic Agents*/Antipsychotic Agents*/pharmacology

  • Source: Psychopharmacology [Psychopharmacology (Berl)] 2024 Nov; Vol. 241 (11), pp. 2223-2239. Date of Electronic Publication: 2024 Jun 10.Publisher: Springer-Verlag Country of Publication: Germany NLM ID: 7608025 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Design of fast-onset antidepressant by dissociating SERT from nNOS in the DRN.

  • Authors : Sun N; State Key Laboratory of Reproductive Medicine, Department of Clinic Pharmacology, School of Pharmacy, Nanjing Medical University, Nanjing 211166, China.; Jiangsu Province Key Laboratory of Anesthesiology, Jiangsu Province Key Laboratory of Anesthesia and Analgesia Application, NMPA Key Laboratory for Research and Evaluation of Narcotic and Psychotropic Drugs, Xuzhou Medical University, Xuzhou 221004, China.

Subjects: Antidepressive Agents*/Antidepressive Agents*/Antidepressive Agents*/chemistry ; Antidepressive Agents*/Antidepressive Agents*/Antidepressive Agents*/pharmacology ; Antidepressive Agents*/Antidepressive Agents*/Antidepressive Agents*/therapeutic use

  • Source: Science (New York, N.Y.) [Science] 2022 Oct 28; Vol. 378 (6618), pp. 390-398. Date of Electronic Publication: 2022 Oct 27.Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 0404511 Publication Model: Print-Electronic

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Academic Journal

Genotyping of patients treated with selective serotonin reuptake inhibitors.

Subjects: Antidepressive Agents*/Antidepressive Agents*/Antidepressive Agents*/blood ; Antidepressive Agents*/Antidepressive Agents*/Antidepressive Agents*/therapeutic use ; Cytochrome P-450 CYP2C19*/Cytochrome P-450 CYP2C19*/Cytochrome P-450 CYP2C19*/genetics

  • Source: Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke [Tidsskr Nor Laegeforen] 2022 Sep 26; Vol. 142 (13). Date of Electronic Publication: 2022 Sep Publisher: Norske Laegeforening Country of Publication: Norway NLM ID: 0413423 Publication Model: Electronic-Print Cited Medium: Internet ISSN:

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Academic Journal

The antidepressant drug vilazodone is an allosteric inhibitor of the serotonin transporter.

  • Authors : Plenge P; Laboratory for Membrane Protein Dynamics. Department of Neuroscience, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.; Yang D

Subjects: Antidepressive Agents/Antidepressive Agents/Antidepressive Agents/*pharmacology ; Serotonin Plasma Membrane Transport Proteins/Serotonin Plasma Membrane Transport Proteins/Serotonin Plasma Membrane Transport Proteins/*metabolism ; Selective Serotonin Reuptake Inhibitors/Selective Serotonin Reuptake Inhibitors/Selective Serotonin Reuptake Inhibitors/*pharmacology

  • Source: Nature communications [Nat Commun] 2021 Aug 20; Vol. 12 (1), pp. 5063. Date of Electronic Publication: 2021 Aug 20.Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN:

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  • 1-10 of  645 results for ""Serotonin Plasma Membrane Transport Proteins""