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Academic Journal

Targeted protein degradation in mycobacteria uncovers antibacterial effects and potentiates antibiotic efficacy.

Subjects: PROTEOLYSIS; BACTERIAL proteins; MYCOBACTERIUM smegmatis

  • Source: Nature Communications; 5/14/2024, Vol. 15 Issue 1, p1-14, 14p

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Academic Journal

Failing upwards: Genetics-based strategies to improve antibiotic discovery and efficacy in Mycobacterium tuberculosis.

Subjects: MYCOBACTERIUM tuberculosis; TUBERCULOSIS; PHARMACOGENOMICS

  • Source: Frontiers in Cellular & Infection Microbiology; 9/15/2022, Vol. 12, p1-8, 8p

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Academic Journal

An Antibacterial β-Lactone Kills Mycobacterium tuberculosis by Disrupting Mycolic Acid Biosynthesis.

Subjects: ANTIBIOTICS; LACTONES; MYCOBACTERIUM tuberculosis

  • Source: Angewandte Chemie International Edition; 1/2/2018, Vol. 57 Issue 1, p348-353, 6p

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Academic Journal

Crystal structures of the transpeptidase domain of the Mycobacterium tuberculosis penicillin-binding protein PonA1 reveal potential mechanisms of antibiotic resistance.

Subjects: BACTERIAL enzymes; CRYSTAL structure; PEPTIDASE

  • Source: FEBS Journal; Jun2016, Vol. 283 Issue 12, p2206-2218, 13p

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Academic Journal

New insights into TB physiology suggest untapped therapeutic opportunities.

Subjects: MYCOBACTERIUM tuberculosis; ANTI-infective agents; HIV

  • Source: Immunological Reviews; Mar2015, Vol. 264 Issue 1, p327-343, 17p

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Academic Journal

Of MICs and Men.

Subjects: *DRUG therapy for tuberculosis; *ANTIBIOTICS; *MICROBIAL sensitivity tests

  • Source: New England Journal of Medicine. 8/30/2018, Vol. 379 Issue 9, p882-883. 2p.

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Academic Journal

Diarylcoumarins inhibit mycolic acid biosynthesis and kill Mycobacterium tuberculosis by targeting FadD32.

Subjects: BIOSYNTHESIS; MYCOBACTERIUM tuberculosis; ANTIBIOTICS

  • Source: Proceedings of the National Academy of Sciences of the United States of America; 7/9/2013, Vol. 110 Issue 28, p11565-11570, 6p

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Academic Journal

Depletion of antibiotic targets has widely varying effects on growth.

Subjects: ANTIBIOTICS; MYCOBACTERIA; BACTERIAL growth

  • Source: Proceedings of the National Academy of Sciences of the United States of America; 3/8/2011, Vol. 108 Issue 10, p4176-4181, 6p, 1 Chart

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Academic Journal

Letting Sleeping dos Lie: Does Dormancy Play a Role in Tuberculosis?

Subjects: DORMANCY (Biology); TUBERCULOSIS; RESUSCITATION

  • Source: Annual Review of Microbiology; Jun2010, Vol. 64 Issue 1, p293-311, 24p

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Academic Journal

The folate pathway is a target for resistance to the drug para-aminosalicylic acid (PAS) in mycobacteria.

Subjects: FOLIC acid; DRUG resistance in microorganisms; ANTIBIOTICS

  • Source: Molecular Microbiology; Jul2004, Vol. 53 Issue 1, p275-282, 8p

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  • 1-10 of  25 results for ""Rubin, Eric J.""