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The synthesis of novel unnatural amino acid by intramolecular aza-Michael addition reaction as multitarget enzyme inhibitors.

• Authors : Abul N; Department of Chemistry, Faculty of Sciences, Atatürk University, Erzurum, Turkey.; Tüzün B

Subjects: Cholinesterase Inhibitors*/Cholinesterase Inhibitors*/Cholinesterase Inhibitors*/chemical synthesis ; Cholinesterase Inhibitors*/Cholinesterase Inhibitors*/Cholinesterase Inhibitors*/chemistry ; Cholinesterase Inhibitors*/Cholinesterase Inhibitors*/Cholinesterase Inhibitors*/pharmacology

• Source: Journal of biochemical and molecular toxicology [J Biochem Mol Toxicol] 2024 Sep; Vol. 38 (9), pp. e23837.Publisher: Wiley Country of Publication: United States NLM ID: 9717231 Publication Model: Print Cited Medium: Internet ISSN: 1099-0461

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Education Full Text (H.W. Wilson)

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Orchestrating the Biosynthesis of an Unnatural Pyrrolysine Amino Acid for Its Direct Incorporation into Proteins Inside Living Cells.

• Authors : Ehrlich, Michael¹; Gattner, Michael J.¹; Viverge, Bastien¹

Subjects: *BIOORGANIC chemistry; *BIOSYNTHESIS; *PYRROLYSINE

• Source: Chemistry - A European Journal. May2015, Vol. 21 Issue 21, p7701-7704. 4p.

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Synthetic amino acids-based short amphipathic peptides exhibit antifungal activity by targeting cell membrane disruption.

• Authors : Aaghaz S; Department of Medicinal Chemistry, National Institute of Pharmaceutical Education and Research, Sahibzada Ajit Singh Nagar, Punjab, India.; Sharma K

Subjects: Antifungal Agents*/Antifungal Agents*/Antifungal Agents*/pharmacology ; Amino Acids*; Amphotericin B/Amphotericin B/Amphotericin B/pharmacology

• Source: Drug development research [Drug Dev Res] 2023 May; Vol. 84 (3), pp. 514-526. Date of Electronic Publication: 2023 Feb 09.Publisher: Wiley-Liss Country of Publication: United States NLM ID: 8204468 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Highly Stereoselective Synthesis of γ,δ‐Unsaturated Quaternary α‐Amino Esters via the Tandem N‐Alkylation/Claisen Rearrangement of α‐Imino Allylesters.

• Authors : Mizota, Isao; Fukaya, Toshikazu; Miwa, Yumi

Subjects: CLAISEN rearrangement; HAMMETT equation; KINETIC isotope effects

• Source: Asian Journal of Organic Chemistry; May2023, Vol. 12 Issue 5, p1-7, 7p

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α-Hydroxy and α-Amino Acids Under Possible Hadean, Volcanic Origin-of-Life Conditions.

• Authors : Huber, Claudia; Wächtershauser, Günter

Subjects: CHEMOAUTOTROPHIC bacteria; BIOORGANIC chemistry; CATALYTIC cracking

• Source: Science. 10/27/2006, Vol. 314 Issue 5799, p630-632. 3p.

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Research from Institute of Bioorganic Chemistry Has Provided New Study Findings on Environment [Amino acid composition of species of the genus Atriplex L. growing in the Aral Sea (Uzbekistan)].

Subjects: BIOORGANIC chemistry; AMINO acids; ATRIPLEX

• Source: Health & Medicine Week; 9/8/2023, p5507-5507, 1p

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New Obesity, Fitness and Wellness Study Findings Have Been Reported by Investigators at School of Sciences (L-proline Catalyzed Synthesis of Dihydropyrano[2,3-c]Pyrazoles and Their Anti-inflammatory Activity).

Subjects: BIOORGANIC chemistry; REPORTERS & reporting; ANTI-inflammatory agents

• Source: Drug Week; 11/22/2024, p1532-1532, 1p

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Tailor‐Made Amino Acids in Pharmaceutical Industry: Synthetic Approaches to Aza‐Tryptophan Derivatives.

• Authors : Han, Jianlin¹ (AUTHOR) ; Lyutenko, Nataliya V.² (AUTHOR); Sorochinsky, Alexander E.² (AUTHOR)

Subjects: *AMINO acids; *BIOORGANIC chemistry; *PEPTIDES

• Source: Chemistry - A European Journal. 12/15/2021, Vol. 27 Issue 70, p17510-17528. 19p.

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Findings on Cancer Detailed by Investigators at Guizhou Normal University (Computer-aided Design of a Fluorescent Mat2a Inhibitor for Visualized Cancer Synthetic Lethality).

Subjects: SULFUR amino acids; ESSENTIAL amino acids; BIOORGANIC chemistryGUIYANG (Guizhou Sheng, China)

• Source: Cancer Weekly; 9/3/2024, p395-395, 1p

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