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Academic Journal

Apolipoprotein E Recognizes Alzheimer's Disease Associated 3-O Sulfation of Heparan Sulfate.

  • Authors : Mah D; Department of Chemistry and Chemical Biology, Department of Biological Sciences, Rensselaer Polytechnic Institute, Troy, NY 12180, USA.; Zhu Y

Subjects: Alzheimer Disease*/Alzheimer Disease*/Alzheimer Disease*/metabolism; Humans ; Apolipoprotein E3/Apolipoprotein E3/Apolipoprotein E3/genetics

  • Source: Angewandte Chemie (International ed. in English) [Angew Chem Int Ed Engl] 2023 Jun 05; Vol. 62 (23), pp. e202212636. Date of Electronic Publication: 2023 Apr 28.Publisher: Wiley-VCH Country of Publication: Germany NLM ID: 0370543 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1521-3773

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Academic Journal

3-O-Sulfation of Heparan Sulfate Enhances Tau Interaction and Cellular Uptake.

  • Authors : Zhao J; Center for Biotechnology and Interdisciplinary Studies, Rensselaer Polytechnic Institute, Troy, NY, USA.; Zhu Y

Subjects: Alzheimer Disease/Alzheimer Disease/Alzheimer Disease/*genetics ; Cell Membrane/Cell Membrane/Cell Membrane/*metabolism ; Heparitin Sulfate/Heparitin Sulfate/Heparitin Sulfate/*chemistry

  • Source: Angewandte Chemie (International ed. in English) [Angew Chem Int Ed Engl] 2020 Jan 27; Vol. 59 (5), pp. 1818-1827. Date of Electronic Publication: 2019 Dec 10.Publisher: Wiley-VCH Country of Publication: Germany NLM ID: 0370543 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1521-3773

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Academic Journal

The role of heparan sulfates in protein aggregation and their potential impact on neurodegeneration.

  • Authors : Maïza A; Cell Growth, Tissue Repair and Regeneration (CRRET), UPEC EA 4397/ERL CNRS 9215, Université Paris Est Créteil, Université Paris Est, Créteil, France.; Chantepie S

Subjects: Protein Aggregates*; Alzheimer Disease/Alzheimer Disease/Alzheimer Disease/*metabolism ; Heparitin Sulfate/Heparitin Sulfate/Heparitin Sulfate/*metabolism

  • Source: FEBS letters [FEBS Lett] 2018 Dec; Vol. 592 (23), pp. 3806-3818. Date of Electronic Publication: 2018 Jun 14.Publisher: John Wiley & Sons Ltd Country of Publication: England NLM ID: 0155157 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Single-entity heparan sulfate glycomimetic clusters for therapeutic applications.

  • Authors : Tyler PC; The Ferrier Research Institute, Victoria University of Wellington, Gracefield Research Centre, Lower Hutt (New Zealand).; Guimond SE

Subjects: Alzheimer Disease/Alzheimer Disease/Alzheimer Disease/*drug therapy ; Amyloid Precursor Protein Secretases/Amyloid Precursor Protein Secretases/Amyloid Precursor Protein Secretases/*antagonists & inhibitors ; Aspartic Acid Endopeptidases/Aspartic Acid Endopeptidases/Aspartic Acid Endopeptidases/*antagonists & inhibitors

  • Source: Angewandte Chemie (International ed. in English) [Angew Chem Int Ed Engl] 2015 Feb 23; Vol. 54 (9), pp. 2718-23. Date of Electronic Publication: 2015 Jan 13.Publisher: Wiley-VCH Country of Publication: Germany NLM ID: 0370543 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1521-3773

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Periodical

Heparan sulfates demonstrate potential for Alzheimer’s disease therapy.

Subjects: Alzheimer Disease/Alzheimer Disease/Alzheimer Disease/*drug therapy ; Heparitin Sulfate/Heparitin Sulfate/Heparitin Sulfate/*therapeutic use; Amyloid Precursor Protein Secretases/Amyloid Precursor Protein Secretases/Amyloid Precursor Protein Secretases/chemistry

  • Source: Future medicinal chemistry [Future Med Chem] 2013 Jul; Vol. 5 (11), pp. 1190.Publisher: Future Science Country of Publication: England NLM ID: 101511162 Publication Model: Print Cited Medium: Internet ISSN: 1756-8927

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Academic Journal

Synthesis of a targeted library of heparan sulfate hexa- to dodecasaccharides as inhibitors of β-secretase: potential therapeutics for Alzheimer's disease.

  • Authors : Schwörer R; Carbohydrate Chemistry, Industrial Research, Ltd. P. O. Box 31310, Lower Hutt, New Zealand.; Zubkova OV

Subjects: Heparitin Sulfate*/Heparitin Sulfate*/Heparitin Sulfate*/analogs & derivatives ; Heparitin Sulfate*/Heparitin Sulfate*/Heparitin Sulfate*/chemical synthesis ; Heparitin Sulfate*/Heparitin Sulfate*/Heparitin Sulfate*/chemistry

  • Source: Chemistry (Weinheim an der Bergstrasse, Germany) [Chemistry] 2013 May 17; Vol. 19 (21), pp. 6817-23. Date of Electronic Publication: 2013 Apr 03.Publisher: Wiley-VCH Country of Publication: Germany NLM ID: 9513783 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1521-3765

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Academic Journal

Sulfation of heparan sulfate associated with amyloid-beta plaques in patients with Alzheimer's disease.

  • Authors : Bruinsma IB; Department of Neurology and Alzheimer Centre, Donders Institute for Brain, Cognition and Behaviour, Centre for Neuroscience, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands. ; te Riet L

Subjects: Alzheimer Disease/Alzheimer Disease/Alzheimer Disease/*metabolism ; Amyloid beta-Peptides/Amyloid beta-Peptides/Amyloid beta-Peptides/*metabolism ; Brain/Brain/Brain/*pathology

  • Source: Acta neuropathologica [Acta Neuropathol] 2010 Feb; Vol. 119 (2), pp. 211-20. Date of Electronic Publication: 2009 Jul 28.Publisher: Springer Verlag Country of Publication: Germany NLM ID: 0412041 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Perlecan binds to the beta-amyloid proteins (A beta) of Alzheimer's disease, accelerates A beta fibril formation, and maintains A beta fibril stability.

  • Authors : Castillo GM; Neuropathology Laboratories, University of Washington, Seattle 98195-6480, U.S.A.; Ngo C

Subjects: Heparan Sulfate Proteoglycans*; Alzheimer Disease/Alzheimer Disease/Alzheimer Disease/*metabolism ; Amyloid beta-Peptides/Amyloid beta-Peptides/Amyloid beta-Peptides/*drug effects

  • Source: Journal of neurochemistry [J Neurochem] 1997 Dec; Vol. 69 (6), pp. 2452-65.Publisher: Wiley on behalf of the International Society for Neurochemistry Country of Publication: England NLM ID: 2985190R Publication Model: Print Cited

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Academic Journal

Human brain beta-secretase contains heparan sulfate glycoconjugates.

  • Authors : Matsumoto A; Department of Radiation Biophysics and Genetics, Kobe University School of Medicine, Japan.; Matsumoto R

Subjects: Alzheimer Disease/Alzheimer Disease/Alzheimer Disease/*enzymology ; Brain/Brain/Brain/*enzymology ; Endopeptidases/Endopeptidases/Endopeptidases/*metabolism

  • Source: Neuroscience letters [Neurosci Lett] 1996 Jun 21; Vol. 211 (2), pp. 105-8.Publisher: Elsevier Scientific Publishers Ireland Country of Publication: Ireland NLM ID: 7600130 Publication Model: Print Cited Medium: Print ISSN:

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Academic Journal

Structure of heparan sulphate from human brain, with special regard to Alzheimer's disease.

Subjects: Alzheimer Disease/Alzheimer Disease/Alzheimer Disease/*metabolism ; Cerebral Cortex/Cerebral Cortex/Cerebral Cortex/*chemistry ; Heparitin Sulfate/Heparitin Sulfate/Heparitin Sulfate/*chemistry

  • Source: The Biochemical journal [Biochem J] 1995 Feb 15; Vol. 306 ( Pt 1), pp. 177-84.Publisher: Published by Portland Press on behalf of the Biochemical Society Country of Publication: England NLM ID: 2984726R Publication Model: Print Cited

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  • 1-10 of  10 results for ""Heparitin Sulfate chemistry""