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Academic Journal

The role of age-associated alpha-synuclein aggregation in a conditional transgenic mouse model of Parkinson's disease: Implications for Lewy body formation.

  • Authors : Li J; Division of Life Science, State Key Laboratory of Molecular Neuroscience, The Hong Kong University of Science and Technology, Hong Kong, China.; Ng KW

Subjects: Aging*/Aging*/Aging*/genetics ; Aging*/Aging*/Aging*/metabolism ; alpha-Synuclein*/alpha-Synuclein*/alpha-Synuclein*/metabolism

  • Source: Journal of neurochemistry [J Neurochem] 2024 Jul; Vol. 168 (7), pp. 1215-1236. Date of Electronic Publication: 2024 May 01.Publisher: Wiley on behalf of the International Society for Neurochemistry Country of Publication: England NLM ID: 2985190R Publication Model: Print-Electronic

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Academic Journal

Alpha-synuclein expression in GnRH neurons of young and old bovine hypothalami.

  • Authors : Niyonzima YB; Faculty of Veterinary Medicine, Yamaguchi University, Yamaguchi-shi, Yamaguchi-ken 1677-1, Japan.; Asato Y

Subjects: Gonadotropin-Releasing Hormone*/Gonadotropin-Releasing Hormone*/Gonadotropin-Releasing Hormone*/metabolism ; Gonadotropin-Releasing Hormone*/Gonadotropin-Releasing Hormone*/Gonadotropin-Releasing Hormone*/genetics ; alpha-Synuclein*/alpha-Synuclein*/alpha-Synuclein*/metabolism

  • Source: Reproduction, fertility, and development [Reprod Fertil Dev] 2024 Sep; Vol. 36.Publisher: Commonwealth Scientific and Industrial Research Organisation Country of Publication: Australia NLM ID: 8907465 Publication Model: Print Cited

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Academic Journal

Human α-synuclein overexpression upregulates SKOR1 in a rat model of simulated nigrostriatal ageing.

  • Authors : Morales-Prieto N; Department of Anatomy and Neuroscience, School of Medicine, University College, Cork, Ireland.; Bevans R

Subjects: Aging*/Aging*/Aging*/metabolism ; alpha-Synuclein*/alpha-Synuclein*/alpha-Synuclein*/metabolism ; alpha-Synuclein*/alpha-Synuclein*/alpha-Synuclein*/genetics

  • Source: Aging cell [Aging Cell] 2024 Jun; Vol. 23 (6), pp. e14155. Date of Electronic Publication: 2024 Mar 26.Publisher: Wiley-Blackwell Country of Publication: England NLM ID: 101130839 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Alpha-synuclein differentially reduces surface expression of N-methyl-d-aspartate receptors in the aging human brain.

  • Authors : Yang W; Department of Neurobiology, Beijing Institute of Geriatrics, Xuanwu Hospital, Capital Medical University, Beijing, China; Center of Parkinson's Disease, Beijing Institute for Brain Disorders, Beijing, China.

Subjects: Aging/Aging/Aging/*genetics ; Aging/Aging/Aging/*metabolism ; Gene Expression/Gene Expression/Gene Expression/*drug effects

  • Source: Neurobiology of aging [Neurobiol Aging] 2020 Jun; Vol. 90, pp. 24-32. Date of Electronic Publication: 2020 Feb 20.Publisher: Elsevier Country of Publication: United States NLM ID: 8100437 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Ageing promotes pathological alpha-synuclein propagation and autonomic dysfunction in wild-type rats.

  • Authors : Van Den Berge N; Department of Clinical Medicine, Aarhus University, Aarhus, Denmark.; Department of Nuclear Medicine and PET, Aarhus University Hospital, Aarhus, Denmark.

Subjects: Aging/Aging/Aging/*pathology ; Primary Dysautonomias/Primary Dysautonomias/Primary Dysautonomias/*etiology ; alpha-Synuclein/alpha-Synuclein/alpha-Synuclein/*toxicity

  • Source: Brain : a journal of neurology [Brain] 2021 Jul 28; Vol. 144 (6), pp. 1853-1868.Publisher: Oxford University Press Country of Publication: England NLM ID: 0372537 Publication Model: Print Cited Medium: Internet ISSN:

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Academic Journal

Age-related increase of alpha-synuclein oligomers is associated with motor disturbances in L61 transgenic mice.

  • Authors : Roshanbin S; Department of Public Health and Caring Sciences, Uppsala University, Uppsala, Sweden.; Aniszewska A

Subjects: Aging/Aging/Aging/*metabolism ; Lewy Bodies/Lewy Bodies/Lewy Bodies/*metabolism ; Parkinson Disease/Parkinson Disease/Parkinson Disease/*genetics

  • Source: Neurobiology of aging [Neurobiol Aging] 2021 May; Vol. 101, pp. 207-220. Date of Electronic Publication: 2021 Jan 28.Publisher: Elsevier Country of Publication: United States NLM ID: 8100437 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Associations of sleep characteristics with alpha-synuclein in cerebrospinal fluid in older adults.

  • Authors : Wang XT; Department of Neurology, Qingdao Municipal Hospital, Qingdao University, Qingdao, China.; Liu FT

Subjects: Aging/Aging/Aging/*physiology ; Alzheimer Disease/Alzheimer Disease/Alzheimer Disease/*cerebrospinal fluid ; Biomarkers/Biomarkers/Biomarkers/*cerebrospinal fluid

  • Source: Annals of clinical and translational neurology [Ann Clin Transl Neurol] 2020 Oct; Vol. 7 (10), pp. 2026-2034. Date of Electronic Publication: 2020 Sep 19.Publisher: Wiley Periodicals, Inc on behalf of American Neurological Association Country of Publication: United States NLM ID: 101623278 Publication Model:

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Academic Journal

Age-dependent elevations of oligomeric and phosphorylated alpha-synuclein synchronously occurs in the brain and gastrointestinal tract of cynomolgus monkeys.

  • Authors : Li X; Department of Neurobiology, Xuanwu Hospital of Capital Medical University, Beijing, China; Clinical Center for Parkinson's Disease, Capital Medical University, China

Subjects: Aging/Aging/Aging/*pathology ; Brain/Brain/Brain/*pathology ; Enteric Nervous System/Enteric Nervous System/Enteric Nervous System/*pathology

  • Source: Neuroscience letters [Neurosci Lett] 2018 Jan 01; Vol. 662, pp. 276-282. Date of Electronic Publication: 2017 Oct 26.Publisher: Elsevier Scientific Publishers Ireland Country of Publication: Ireland NLM ID: 7600130 Publication Model: Print-Electronic Cited Medium:

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Academic Journal

The influence of tau, amyloid, alpha-synuclein, TDP-43, and vascular pathology in clinically normal elderly individuals.

Subjects: Aging/Aging/Aging/*pathology ; Aging/Aging/Aging/*psychology ; Amyloid beta-Peptides/Amyloid beta-Peptides/Amyloid beta-Peptides/*metabolism

  • Source: Neurobiology of aging [Neurobiol Aging] 2019 May; Vol. 77, pp. 26-36. Date of Electronic Publication: 2019 Jan 21.Publisher: Elsevier Country of Publication: United States NLM ID: 8100437 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Age-dependent alpha-synuclein accumulation is correlated with elevation of mitochondrial TRPC3 in the brains of monkeys and mice.

  • Authors : Chen M; Key Laboratory of Neural Regeneration and Repair, Department of Neurobiology, Capital Medical University, 10 Xi Tou Tiao, You Anmen, Beijing, 100069, China.; Center for Parkinson's Disease Beijing Institute for Brain Disorders, Key Laboratory for Neurodegenerative Diseases of the Ministry of Education, Beijing, China.

Subjects: Aging/Aging/Aging/*metabolism ; Brain/Brain/Brain/*metabolism ; Mitochondria/Mitochondria/Mitochondria/*metabolism

  • Source: Journal of neural transmission (Vienna, Austria : 1996) [J Neural Transm (Vienna)] 2017 Apr; Vol. 124 (4), pp. 441-453. Date of Electronic Publication: 2016 Nov 30.Publisher: Springer-Verlag Country of Publication: Austria NLM ID: 9702341 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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  • 1-10 of  1,373 results for ""alpha-Synuclein""