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Academic Journal

Selective Phosphodiesterase 1 Inhibition Ameliorates Vascular Function, Reduces Inflammatory Response, and Lowers Blood Pressure in Aging Animals.

  • Authors : Golshiri K; Dept. of Internal Medicine (K.G., E.A.A., E.R.-B., I.M.V.d.B.-G., A.M., R.d.V., A.H.J.D., A.J.M.R.), Dept. of Molecular Genetics (I.v.d.P., R.B.), Dept. of Vascular Surgery (I.v.d.P.), Erasmus Medical Center, Rotterdam, The Netherlands, and Intra-Cellular Therapies, Inc., New York, New York (S.D., W.Y., G.L.S., R.E.D.).; Ataei Ataabadi E

Subjects: Aging*/Aging*/Aging*/drug effects ; Blood Pressure*/Blood Pressure*/Blood Pressure*/drug effects ; Cyclic Nucleotide Phosphodiesterases, Type 1*/Cyclic Nucleotide Phosphodiesterases, Type 1*/Cyclic Nucleotide Phosphodiesterases, Type 1*/antagonists & inhibitors

  • Source: The Journal of pharmacology and experimental therapeutics [J Pharmacol Exp Ther] 2021 Aug; Vol. 378 (2), pp. 173-183. Date of Electronic Publication: 2021 Jun 07.Publisher: American Society for Pharmacology and Experimental Therapeutics Country of Publication: United States NLM ID: 0376362 Publication Model:

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Academic Journal

The importance of the nitric oxide-cGMP pathway in age-related cardiovascular disease: Focus on phosphodiesterase-1 and soluble guanylate cyclase.

  • Authors : Golshiri K; Division of Vascular Medicine and Pharmacology, Department of Internal Medicine, Erasmus Medical Center, Rotterdam, The Netherlands.; Ataei Ataabadi E

Subjects: Aging/Aging/Aging/*metabolism ; Cardiovascular Diseases/Cardiovascular Diseases/Cardiovascular Diseases/*metabolism ; Cyclic GMP/Cyclic GMP/Cyclic GMP/*metabolism

  • Source: Basic & clinical pharmacology & toxicology [Basic Clin Pharmacol Toxicol] 2020 Aug; Vol. 127 (2), pp. 67-80. Date of Electronic Publication: 2019 Oct 03.Publisher: Blackwell Country of Publication: England NLM ID: 101208422 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1742-7843

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Academic Journal

Phosphodiesterase 1 regulation is a key mechanism in vascular aging.

  • Authors : Bautista Niño PK; Department of Internal Medicine, Division of Vascular Disease and Pharmacology, Erasmus MC Rotterdam, 3015 CN, The Netherlands Department of Epidemiology, Erasmus MC Rotterdam, 3015 CN, The Netherlands.; Durik M

Subjects: Vasodilation*/Vasodilation*/Vasodilation*/drug effects; Aging/Aging/Aging/*metabolism ; Cyclic Nucleotide Phosphodiesterases, Type 1/Cyclic Nucleotide Phosphodiesterases, Type 1/Cyclic Nucleotide Phosphodiesterases, Type 1/*metabolism

  • Source: Clinical science (London, England : 1979) [Clin Sci (Lond)] 2015 Dec; Vol. 129 (12), pp. 1061-75. Date of Electronic Publication: 2015 Jun 25.Publisher: Portland Press on behalf of the Medical Research Society and the Biochemical Society Country of Publication: England NLM ID: 7905731 Publication Model:

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Academic Journal

Cyclic nucleotide phosphodiesterase 1 and vascular aging.

  • Authors : Yan C; Aab Cardiovascular Research Institute, University of Rochester, 601 Elmwood Avenue, Rochester, NY 14642, U.S.A. .

Subjects: Vasodilation*; Aging/Aging/Aging/*metabolism ; Cyclic Nucleotide Phosphodiesterases, Type 1/Cyclic Nucleotide Phosphodiesterases, Type 1/Cyclic Nucleotide Phosphodiesterases, Type 1/*metabolism

  • Source: Clinical science (London, England : 1979) [Clin Sci (Lond)] 2015 Dec; Vol. 129 (12), pp. 1077-81. Date of Electronic Publication: 2015 Sep 15.Publisher: Portland Press on behalf of the Medical Research Society and the Biochemical Society Country of Publication: England NLM ID: 7905731 Publication Model:

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Academic Journal

Synchronous patchy pattern of gene expression for adenylyl cyclase and phosphodiesterase but discrete expression for G-protein in developing rat striatum.

Subjects: Embryonic and Fetal Development* ; Gene Expression Regulation*; 3',5'-Cyclic-AMP Phosphodiesterases/3',5'-Cyclic-AMP Phosphodiesterases/3',5'-Cyclic-AMP Phosphodiesterases/*biosynthesis

  • Source: Brain research. Molecular brain research [Brain Res Mol Brain Res] 1995 Nov; Vol. 33 (2), pp. 185-91.Publisher: Elsevier Science Publishers Country of Publication: Netherlands NLM ID: 8908640 Publication Model: Print Cited Medium: Print ISSN:

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Changes in activities of calmodulin-mediated enzymes in rat brain during aging.

Subjects: Aging*; Brain/Brain/Brain/*metabolism ; Calmodulin/Calmodulin/Calmodulin/*metabolism

  • Source: Mechanisms of ageing and development [Mech Ageing Dev] 1984 Aug; Vol. 26 (2-3), pp. 231-9.Publisher: Elsevier Science Ireland Country of Publication: Ireland NLM ID: 0347227 Publication Model: Print Cited Medium: Print ISSN: 0047-6374

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  • 1-6 of  6 results for ""Cyclic Nucleotide Phosphodiesterases, Type 1""