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Academic Journal

Insulin activates microglia and increases COX-2/IL-1β expression in young but not in aged hippocampus.

  • Authors : Haas CB; Laboratory of Neurotrauma and Biomarkers, Departament of Biochemistry, Programa de Pós-graduação em Bioquímica, Universidade Federal do Rio Grande do Sul (UFRGS), Porto Alegre, RS, Brazil; Department of Biomedical Sciences of Cells & Systems, Section Molecular Neurobiology, University of Groningen, University Medical Center Groningen (UMCG), Groningen, the Netherlands

Subjects: Aging/Aging/Aging/*metabolism ; Cyclooxygenase 2/Cyclooxygenase 2/Cyclooxygenase 2/*biosynthesis ; Hippocampus/Hippocampus/Hippocampus/*metabolism

  • Source: Brain research [Brain Res] 2020 Aug 15; Vol. 1741, pp. 146884. Date of Electronic Publication: 2020 May 15.Publisher: Elsevier/North-Holland Biomedical Press Country of Publication: Netherlands NLM ID: 0045503 Publication Model: Print-Electronic Cited Medium:

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Academic Journal

Endothelium-specific deletion of amyloid-β precursor protein exacerbates endothelial dysfunction induced by aging.

  • Authors : d'Uscio LV; Departments of Anesthesiology and Perioperative Medicine, Mayo Clinic, Rochester, MN 55902, USA.; Katusic ZS

Subjects: Aging/Aging/Aging/*physiology ; Amyloid beta-Protein Precursor/Amyloid beta-Protein Precursor/Amyloid beta-Protein Precursor/*genetics ; Endothelium, Vascular/Endothelium, Vascular/Endothelium, Vascular/*metabolism

  • Source: Aging [Aging (Albany NY)] 2021 Aug 12; Vol. 13 (15), pp. 19165-19185. Date of Electronic Publication: 2021 Aug 12.Publisher: Impact Journals, LLC Country of Publication: United States NLM ID: 101508617 Publication Model: Print-Electronic Cited Medium: Internet

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Academic Journal

Does the Urothelium of Old Mice Regenerate after Chitosan Injury as Quickly as the Urothelium of Young Mice?

  • Authors : Erzar E; Department of Biotechnology, Jožef Stefan Institute, 1000 Ljubljana, Slovenia.; Kerec Kos M

Subjects: Regeneration*/Regeneration*/Regeneration*/drug effects; Aging/Aging/Aging/*physiology ; Chitosan/Chitosan/Chitosan/*toxicity

  • Source: International journal of molecular sciences [Int J Mol Sci] 2020 May 15; Vol. 21 (10). Date of Electronic Publication: 2020 May 15.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067

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Academic Journal

Swimming exercise stimulates IGF1/ PI3K/Akt and AMPK/SIRT1/PGC1α survival signaling to suppress apoptosis and inflammation in aging hippocampus.

  • Authors : Lin JY; Department of Medical Imaging and Radiological Science, Central Taiwan University of Science and Technology, Taichung, Taiwan.; Kuo WW

Subjects: Signal Transduction*; Aging/Aging/Aging/*physiology ; Hippocampus/Hippocampus/Hippocampus/*physiology

  • Source: Aging [Aging (Albany NY)] 2020 Apr 22; Vol. 12 (8), pp. 6852-6864. Date of Electronic Publication: 2020 Apr 22.Publisher: Impact Journals, LLC Country of Publication: United States NLM ID: 101508617 Publication Model: Print-Electronic Cited Medium: Internet

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Academic Journal

COX-2/sEH dual inhibitor PTUPB alleviates bleomycin-induced pulmonary fibrosis in mice via inhibiting senescence.

  • Authors : Zhang CY; Department of Physiology, Xiangya School of Medicine, Central South University, Changsha, China.; Duan JX

Subjects: Aging/Aging/Aging/*drug effects ; Cyclooxygenase 2/Cyclooxygenase 2/Cyclooxygenase 2/*metabolism ; Enzyme Inhibitors/Enzyme Inhibitors/Enzyme Inhibitors/*pharmacology

  • Source: The FEBS journal [FEBS J] 2020 Apr; Vol. 287 (8), pp. 1666-1680. Date of Electronic Publication: 2019 Nov 08.Publisher: Published by Blackwell Pub. on behalf of the Federation of European Biochemical Societies Country of Publication: England NLM ID: 101229646 Publication

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Academic Journal

Transgenic expression of cyclooxygenase-2 (COX2) causes premature aging phenotypes in mice.

  • Authors : Kim J; Department of Biological Sciences, University of South Carolina, Columbia, SC 29208, USA.; Center for Colon Cancer Research, University of South Carolina, Columbia, SC 29208, USA.

Subjects: Phenotype*; Aging/Aging/Aging/*genetics ; Aging, Premature/Aging, Premature/Aging, Premature/*genetics

  • Source: Aging [Aging (Albany NY)] 2016 Oct 07; Vol. 8 (10), pp. 2392-2406.Publisher: Impact Journals, LLC Country of Publication: United States NLM ID: 101508617 Publication Model: Print Cited Medium: Internet ISSN:

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Academic Journal

The roles of p38 MAPK → COX2 and NF-κB → COX2 signal pathways in age-related testosterone reduction.

  • Authors : Zhao Y; Department of Histology and Embryology, Hebei Medical University, Shijiazhuang, 050017, China.; Liu X

Subjects: Aging/Aging/Aging/*metabolism ; Testis/Testis/Testis/*metabolism ; Testosterone/Testosterone/Testosterone/*metabolism

  • Source: Scientific reports [Sci Rep] 2019 Jul 22; Vol. 9 (1), pp. 10556. Date of Electronic Publication: 2019 Jul 22.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN:

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Academic Journal

Long-Term Aspirin Administration Has No Effect on Erectile Function: Evidence from Adult Rats and Ageing Rat Model.

  • Authors : Li T; The Andrology Laboratory, West China Hospital, Sichuan University, Chengdu, Sichuan, China.; Department of Urology, West China Hospital, Sichuan University, Chengdu, Sichuan, China.

Subjects: Aging*/Aging*/Aging*/drug effects; Anti-Inflammatory Agents, Non-Steroidal/Anti-Inflammatory Agents, Non-Steroidal/Anti-Inflammatory Agents, Non-Steroidal/*pharmacology ; Aspirin/Aspirin/Aspirin/*pharmacology

  • Source: Scientific reports [Sci Rep] 2019 May 28; Vol. 9 (1), pp. 7941. Date of Electronic Publication: 2019 May 28.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN:

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Academic Journal

Loss of NF-κB p50 function synergistically augments microglial priming in the middle-aged brain.

  • Authors : Taetzsch T; Department of Anatomy and Neurobiology, Virginia Commonwealth University Medical Campus, Richmond, VA, 23298, USA.; Benusa S

Subjects: Aging/Aging/Aging/*pathology ; Brain/Brain/Brain/*metabolism ; Inflammation/Inflammation/Inflammation/*pathology

  • Source: Journal of neuroinflammation [J Neuroinflammation] 2019 Mar 12; Vol. 16 (1), pp. 60. Date of Electronic Publication: 2019 Mar 12.Publisher: BioMed Central Country of Publication: England NLM ID: 101222974 Publication Model: Electronic Cited Medium: Internet ISSN: 1742-2094

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Academic Journal

Endothelial SIRT1 prevents age-induced impairment of vasodilator responses by enhancing the expression and activity of soluble guanylyl cyclase in smooth muscle cells.

  • Authors : Guo Y; State Key Laboratory of Pharmaceutical Biotechnology and Department of Pharmacology and Pharmacy, Li Ka Shing Faculty of Medicine, The University of Hong Kong, LKS Faculty of Medicine Building, 21 Sassoon Road, Pokfulam, Hong Kong, China.; Xu C

Subjects: Paracrine Communication* ; Vasodilation*/Vasodilation*/Vasodilation*/drug effects; Aging/Aging/Aging/*metabolism

  • Source: Cardiovascular research [Cardiovasc Res] 2019 Mar 01; Vol. 115 (3), pp. 678-690.Publisher: Oxford Journals Country of Publication: England NLM ID: 0077427 Publication Model: Print Cited Medium: Internet ISSN: 1755-3245

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  • 1-10 of  188 results for ""CYCLOOXYGENASE 2""