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Academic Journal

ADAMTS-5: A difficult teenager turning 20.

  • Authors : Santamaria S; Centre for Haematology, London, UK.

Subjects: ADAMTS5 Protein/ADAMTS5 Protein/ADAMTS5 Protein/*metabolism ; Aggrecans/Aggrecans/Aggrecans/*metabolism ; Cardiovascular Diseases/Cardiovascular Diseases/Cardiovascular Diseases/*enzymology

  • Source: International journal of experimental pathology [Int J Exp Pathol] 2020 Feb; Vol. 101 (1-2), pp. 4-20. Date of Electronic Publication: 2020 Mar 27.Publisher: Wiley Country of Publication: England NLM ID: 9014042 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1365-2613

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Report

Effect of Mechanical Stress in Combination with Verapamil on Levels of Aggrecan and ADAMTS-5 mRNAs and Proteins in Human Osteoarthritic Chondrocyte/Agarose Constructs.

  • Authors : Luo D; Department of Rheumatology, Huadong Hospital, Fudan University, Shanghai 200040, China.; Shen Y

Subjects: Stress, Mechanical*; ADAMTS5 Protein/ADAMTS5 Protein/ADAMTS5 Protein/*metabolism ; Aggrecans/Aggrecans/Aggrecans/*metabolism

  • Source: Chinese medical journal [Chin Med J (Engl)] 2018 Sep 20; Vol. 131 (18), pp. 2229-2231.Publisher: Chinese Medical Association ; produced by Wolters Kluwer Country of Publication: China NLM ID: 7513795 Publication Model: Print Cited Medium:

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Academic Journal

Adamts5 -/- Mice Exhibit Altered Aggrecan Proteolytic Profiles That Correlate With Ascending Aortic Anomalies.

  • Authors : Dupuis LE; From the Department of Regenerative Medicine and Cell Biology, Medical University of South Carolina, Charleston (L.E.D., E.L.N., B.H., S.C.P., A.R.-D., C.B.K.).; Nelson EL

Subjects: Gene Expression Regulation, Developmental*; ADAMTS5 Protein/ADAMTS5 Protein/ADAMTS5 Protein/*genetics ; Aggrecans/Aggrecans/Aggrecans/*genetics

  • Source: Arteriosclerosis, thrombosis, and vascular biology [Arterioscler Thromb Vasc Biol] 2019 Oct; Vol. 39 (10), pp. 2067-2081. Date of Electronic Publication: 2019 Aug 01.Publisher: Lippincott Williams & Wilkins Country of Publication: United States NLM ID: 9505803 Publication Model: Print-Electronic Cited Medium:

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Academic Journal

Single Nucleotide Variants of Candidate Genes in Aggrecan Metabolic Pathway Are Associated with Lumbar Disc Degeneration and Modic Changes.

  • Authors : Perera RS; Department of Allied Health Sciences, Faculty of Medicine, University of Colombo, Colombo, Sri Lanka.; Dissanayake PH

Subjects: Polymorphism, Single Nucleotide*; ADAMTS4 Protein/ADAMTS4 Protein/ADAMTS4 Protein/*genetics ; ADAMTS5 Protein/ADAMTS5 Protein/ADAMTS5 Protein/*genetics Intervertebral disc disease

  • Source: PloS one [PLoS One] 2017 Jan 12; Vol. 12 (1), pp. e0169835. Date of Electronic Publication: 2017 Jan 12 (Print Publication: 2017).Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: eCollection Cited Medium: Internet

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Academic Journal

Saxagliptin suppresses degradation of type II collagen and aggrecan in primary human chondrocytes: a therapeutic implication in osteoarthritis.

  • Authors : Hu N; a Department of Orthopaedics, The First Affiliated Hospital of Chongqing Medical University , Chongqing , China.; Gong X

Subjects: Adamantane/Adamantane/Adamantane/*analogs & derivatives ; Aggrecans/Aggrecans/Aggrecans/*metabolism ; Chondrocytes/Chondrocytes/Chondrocytes/*drug effects

  • Source: Artificial cells, nanomedicine, and biotechnology [Artif Cells Nanomed Biotechnol] 2019 Dec; Vol. 47 (1), pp. 3239-3245.Publisher: Taylor & Francis Country of Publication: England NLM ID: 101594777 Publication Model: Print Cited Medium: Internet ISSN: 2169-141X

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Academic Journal

Massive aggrecan and versican accumulation in thoracic aortic aneurysm and dissection.

  • Authors : Cikach FS; Cleveland Clinic Lerner College of Medicine of Case Western Reserve University, Cleveland, Ohio, USA.; Koch CD

Subjects: Aggrecans/Aggrecans/Aggrecans/*metabolism ; Aortic Dissection/Aortic Dissection/Aortic Dissection/*pathology ; Aortic Aneurysm, Thoracic/Aortic Aneurysm, Thoracic/Aortic Aneurysm, Thoracic/*pathology

  • Source: JCI insight [JCI Insight] 2018 Mar 08; Vol. 3 (5). Date of Electronic Publication: 2018 Mar 08.Publisher: American Society for Clinical Investigation Country of Publication: United States NLM ID: 101676073 Publication Model: Electronic Cited Medium:

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Academic Journal

An aggrecan fragment drives osteoarthritis pain through Toll-like receptor 2.

  • Authors : Miller RE; Department of Internal Medicine, Division of Rheumatology, Rush University Medical Center, Chicago, Illinois, USA.; Ishihara S

Subjects: Aggrecans/Aggrecans/Aggrecans/*metabolism ; Arthralgia/Arthralgia/Arthralgia/*metabolism ; Osteoarthritis/Osteoarthritis/Osteoarthritis/*metabolism

  • Source: JCI insight [JCI Insight] 2018 Mar 22; Vol. 3 (6). Date of Electronic Publication: 2018 Mar 22.Publisher: American Society for Clinical Investigation Country of Publication: United States NLM ID: 101676073 Publication Model: Electronic Cited Medium:

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Academic Journal

Extracellular Matrix Proteomics Reveals Interplay of Aggrecan and Aggrecanases in Vascular Remodeling of Stented Coronary Arteries.

  • Authors : Suna G; King's British Heart Foundation Centre, King's College London, United Kingdom (G.S., M.L., J.B.-B., X.Y., U.M., F.B., R.L., M.F., R.H., C.M., C.M.S., M.M.).; Wojakowski W

Subjects: Aggrecans* ; Stents* ; Vascular Remodeling*

  • Source: Circulation [Circulation] 2018 Jan 09; Vol. 137 (2), pp. 166-183. Date of Electronic Publication: 2017 Oct 13.Publisher: Lippincott Williams & Wilkins Country of Publication: United States NLM ID: 0147763 Publication Model: Print-Electronic Cited Medium:

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Academic Journal

Matriptase Induction of Metalloproteinase-Dependent Aggrecanolysis In Vitro and In Vivo: Promotion of Osteoarthritic Cartilage Damage by Multiple Mechanisms.

Subjects: Aggrecans/Aggrecans/Aggrecans/*drug effects ; Cartilage, Articular/Cartilage, Articular/Cartilage, Articular/*drug effects ; Osteoarthritis, Knee/Osteoarthritis, Knee/Osteoarthritis, Knee/*metabolism

  • Source: Arthritis & rheumatology (Hoboken, N.J.) [Arthritis Rheumatol] 2017 Aug; Vol. 69 (8), pp. 1601-1611. Date of Electronic Publication: 2017 Jul 05.Publisher: Wiley Country of Publication: United States NLM ID: 101623795 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

A Disintegrin and Metalloproteinase with Thrombospondin Motifs-5 (ADAMTS-5) Forms Catalytically Active Oligomers.

  • Authors : Kosasih HJ; From the Department of Paediatrics, University of Melbourne, Parkville 3052, Australia, the Murdoch Childrens Research Institute, Royal Children's Hospital, Parkville 3052, Australia.; Last K

Subjects: ADAM Proteins/ADAM Proteins/ADAM Proteins/*metabolism ; Aggrecans/Aggrecans/Aggrecans/*metabolism ; Arthritis, Experimental/Arthritis, Experimental/Arthritis, Experimental/*enzymology

  • Source: The Journal of biological chemistry [J Biol Chem] 2016 Feb 12; Vol. 291 (7), pp. 3197-208. Date of Electronic Publication: 2015 Dec 14.Publisher: Elsevier Inc. on behalf of American Society for Biochemistry and Molecular Biology Country of Publication: United States NLM ID: 2985121R Publication

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