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Academic Journal

5'-Phosphonate modified oligoadenylates as potent activators of human RNase L.

  • Authors : Lášek T; IOCB Prague, Flemingovo nam. 2, 160 00 Prague, Czech Republic; UCT Prague, Technická 5, 166 28, Prague, Czech Republic.

Subjects: Adenine Nucleotides/Adenine Nucleotides/Adenine Nucleotides/*pharmacology ; Endoribonucleases/Endoribonucleases/Endoribonucleases/*metabolism ; Oligoribonucleotides/Oligoribonucleotides/Oligoribonucleotides/*pharmacology

  • Source: Bioorganic & medicinal chemistry [Bioorg Med Chem] 2022 Feb 15; Vol. 56, pp. 116632. Date of Electronic Publication: 2022 Jan 19.Publisher: Elsevier Science Country of Publication: England NLM ID: 9413298 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Structural basis of cyclic oligoadenylate binding to the transcription factor Csa3 outlines cross talk between type III and type I CRISPR systems.

  • Authors : Xia P; Department of Biological Sciences, University of Delaware, Newark, Delaware, USA.; Dutta A

Subjects: Adenine Nucleotides*/Adenine Nucleotides*/Adenine Nucleotides*/chemistry ; Adenine Nucleotides*/Adenine Nucleotides*/Adenine Nucleotides*/metabolism ; Clustered Regularly Interspaced Short Palindromic Repeats*

  • Source: The Journal of biological chemistry [J Biol Chem] 2022 Feb; Vol. 298 (2), pp. 101591. Date of Electronic Publication: 2022 Jan 14.Publisher: Elsevier Inc. on behalf of American Society for Biochemistry and Molecular Biology Country of Publication: United States NLM ID: 2985121R Publication

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Academic Journal

Structural basis of cyclic oligoadenylate degradation by ancillary Type III CRISPR-Cas ring nucleases.

  • Authors : Molina R; Structural Molecular Biology Group, Novo Nordisk Foundation Centre for Protein Research, Faculty of Health and Medical Sciences University of Copenhagen, Blegdamsvej 3-B, Copenhagen, 2200, Denmark.; Jensen ALG

Subjects: CRISPR-Cas Systems*; Adenine Nucleotides/Adenine Nucleotides/Adenine Nucleotides/*metabolism ; CRISPR-Associated Proteins/CRISPR-Associated Proteins/CRISPR-Associated Proteins/*metabolism

  • Source: Nucleic acids research [Nucleic Acids Res] 2021 Dec 02; Vol. 49 (21), pp. 12577-12590.Publisher: Oxford University Press Country of Publication: England NLM ID: 0411011 Publication Model: Print Cited Medium: Internet ISSN:

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Academic Journal

The Card1 nuclease provides defence during type III CRISPR immunity.

  • Authors : Rostøl JT; Laboratory of Bacteriology, The Rockefeller University, New York, NY, USA.; Xie W

Subjects: Adenine Nucleotides/Adenine Nucleotides/Adenine Nucleotides/*metabolism ; CRISPR-Cas Systems/CRISPR-Cas Systems/CRISPR-Cas Systems/*immunology ; DNA, Single-Stranded/DNA, Single-Stranded/DNA, Single-Stranded/*metabolism

  • Source: Nature [Nature] 2021 Feb; Vol. 590 (7847), pp. 624-629. Date of Electronic Publication: 2021 Jan 18.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 0410462 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

2'-5'-Oligoadenylate synthetase-like protein inhibits intracellular M. tuberculosis replication and promotes proinflammatory cytokine secretion.

  • Authors : Leisching G; SA MRC Centre for TB Research, DST-NRF Centre of Excellence for Biomedical Tuberculosis Research, Division of Molecular Biology and Human Genetics, Faculty of Medicine and Health Sciences, Stellenbosch University, South Africa. Electronic address: .; Ali A

Subjects: 2',5'-Oligoadenylate Synthetase/2',5'-Oligoadenylate Synthetase/2',5'-Oligoadenylate Synthetase/*metabolism ; Adenine Nucleotides/Adenine Nucleotides/Adenine Nucleotides/*metabolism ; Cytokines/Cytokines/Cytokines/*metabolism

  • Source: Molecular immunology [Mol Immunol] 2020 Feb; Vol. 118, pp. 73-78. Date of Electronic Publication: 2019 Dec 17.Publisher: Pergamon Press Country of Publication: England NLM ID: 7905289 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Identification of a novel member of 2H phosphoesterases, 2',5'-oligoadenylate degrading ribonuclease from the oyster Crassostrea gigas.

  • Authors : Lopp A; Department of Chemistry and Biotechnology, Division of Gene Technology, Tallinn University of Technology, Akadeemia Tee 15, Tallinn, 12618, Estonia. Electronic address: .; Reintamm T

Subjects: Adenine Nucleotides*/Adenine Nucleotides*/Adenine Nucleotides*/chemistry ; Adenine Nucleotides*/Adenine Nucleotides*/Adenine Nucleotides*/metabolism ; Oligoribonucleotides*/Oligoribonucleotides*/Oligoribonucleotides*/chemistry

  • Source: Biochimie [Biochimie] 2019 Jan; Vol. 156, pp. 181-195. Date of Electronic Publication: 2018 Sep 05.Publisher: Editions Scientifiques Elsevier Country of Publication: France NLM ID: 1264604 Publication Model: Print-Electronic Cited Medium: Internet

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Academic Journal

Cyclic oligoadenylate signalling mediates Mycobacterium tuberculosis CRISPR defence.

  • Authors : Grüschow S; Biomedical Sciences Research Complex, School of Biology, University of St Andrews, St Andrews KY16 9ST, UK.; Athukoralage JS

Subjects: Adenine Nucleotides/Adenine Nucleotides/Adenine Nucleotides/*genetics ; CRISPR-Cas Systems/CRISPR-Cas Systems/CRISPR-Cas Systems/*genetics ; Clustered Regularly Interspaced Short Palindromic Repeats/Clustered Regularly Interspaced Short Palindromic Repeats/Clustered Regularly Interspaced Short Palindromic Repeats/*genetics

  • Source: Nucleic acids research [Nucleic Acids Res] 2019 Sep 26; Vol. 47 (17), pp. 9259-9270.Publisher: Oxford University Press Country of Publication: England NLM ID: 0411011 Publication Model: Print Cited Medium: Internet ISSN:

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Academic Journal

Second Messenger cA 4 Formation within the Composite Csm1 Palm Pocket of Type III-A CRISPR-Cas Csm Complex and Its Release Path.

  • Authors : Jia N; Structural Biology Program Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA. Electronic address: .; Jones R

Subjects: CRISPR-Cas Systems* ; Second Messenger Systems*; Adenine Nucleotides/Adenine Nucleotides/Adenine Nucleotides/*chemistry

  • Source: Molecular cell [Mol Cell] 2019 Sep 05; Vol. 75 (5), pp. 933-943.e6. Date of Electronic Publication: 2019 Jul 17.Publisher: Cell Press Country of Publication: United States NLM ID: 9802571 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Regulation of cyclic oligoadenylate synthesis by the Staphylococcus epidermidis Cas10-Csm complex.

  • Authors : Nasef M; Department of Chemistry and Biochemistry, University of Alabama, Tuscaloosa, Alabama 35487, USA.; Muffly MC

Subjects: Adenine Nucleotides/Adenine Nucleotides/Adenine Nucleotides/*metabolism ; CRISPR-Associated Proteins/CRISPR-Associated Proteins/CRISPR-Associated Proteins/*metabolism ; Oligoribonucleotides/Oligoribonucleotides/Oligoribonucleotides/*metabolism

  • Source: RNA (New York, N.Y.) [RNA] 2019 Aug; Vol. 25 (8), pp. 948-962. Date of Electronic Publication: 2019 May 10.Publisher: Cold Spring Harbor Laboratory Press Country of Publication: United States NLM ID: 9509184 Publication Model: Print-Electronic Cited Medium:

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Academic Journal

Investigation of the cyclic oligoadenylate signaling pathway of type III CRISPR systems.

  • Authors : Rouillon C; Biomedical Sciences Research Complex, School of Biology, University of St Andrews, St Andrews, Fife, United Kingdom.; Athukoralage JS

Subjects: CRISPR-Cas Systems*; Adenine Nucleotides/Adenine Nucleotides/Adenine Nucleotides/*metabolism ; Archaeal Proteins/Archaeal Proteins/Archaeal Proteins/*metabolism

  • Source: Methods in enzymology [Methods Enzymol] 2019; Vol. 616, pp. 191-218. Date of Electronic Publication: 2019 Jan 12.Publisher: Academic Press Country of Publication: United States NLM ID: 0212271 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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  • 1-10 of  511 results for ""Oligoribonucleotides""