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Academic Journal

XAF1 is secreted from stressed tumor cells to activate T cell-mediated tumor surveillance via Lck-ERK signaling.

  • Authors : Ahn J; Department of Life Sciences, Korea University, Seoul 02841, Republic of Korea.; Jang SH

Subjects: T-Lymphocytes*/T-Lymphocytes*/T-Lymphocytes*/metabolism ; T-Lymphocytes*/T-Lymphocytes*/T-Lymphocytes*/immunology ; Adaptor Proteins, Signal Transducing*/Adaptor Proteins, Signal Transducing*/Adaptor Proteins, Signal Transducing*/metabolism

  • Source: Neoplasia (New York, N.Y.) [Neoplasia] 2025 Jan; Vol. 59, pp. 101094. Date of Electronic Publication: 2024 Nov 29.Publisher: Elsevier Country of Publication: United States NLM ID: 100886622 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Novel causative variants in Legius syndrome: SPRED1 Genotype spectrum expansion.

  • Authors : Chelleri C; Pediatric Neurology and Neuromuscular Disorders Unit, IRCCS Istituto Giannina Gaslini, Genoa, Italy.; Brolatti N

Subjects: Cafe-au-Lait Spots*/Cafe-au-Lait Spots*/Cafe-au-Lait Spots*/genetics ; Cafe-au-Lait Spots*/Cafe-au-Lait Spots*/Cafe-au-Lait Spots*/pathology ; Genotype* Legius syndrome

  • Source: American journal of medical genetics. Part A [Am J Med Genet A] 2024 Dec; Vol. 194 (12), pp. e63824. Date of Electronic Publication: 2024 Jul 19.Publisher: Wiley-Blackwell Country of Publication: United States NLM ID: 101235741 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

TBK1-associated adapters TANK and AZI2 protect mice against TNF-induced cell death and severe autoinflammatory diseases.

  • Authors : Ujevic A; Laboratory of Immunity & Cell Communication, Division BIOCEV, First Faculty of Medicine, Charles University, Vestec, Czech Republic.; Knizkova D

Subjects: Protein Serine-Threonine Kinases*/Protein Serine-Threonine Kinases*/Protein Serine-Threonine Kinases*/metabolism ; Protein Serine-Threonine Kinases*/Protein Serine-Threonine Kinases*/Protein Serine-Threonine Kinases*/genetics ; Tumor Necrosis Factor-alpha*/Tumor Necrosis Factor-alpha*/Tumor Necrosis Factor-alpha*/metabolism

  • Source: Nature communications [Nat Commun] 2024 Nov 19; Vol. 15 (1), pp. 10013. Date of Electronic Publication: 2024 Nov 19.Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN:

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Academic Journal

XAF1 antagonizes TRIM28 activity through the assembly of a ZNF313-mediated destruction complex to suppress tumor malignancy.

  • Authors : Jang SH; Department of Life Sciences, Korea University, Seoul, 02841, Republic of Korea.; Choi HW

Subjects: Ubiquitination* ; Tripartite Motif-Containing Protein 28*/Tripartite Motif-Containing Protein 28*/Tripartite Motif-Containing Protein 28*/metabolism ; Tripartite Motif-Containing Protein 28*/Tripartite Motif-Containing Protein 28*/Tripartite Motif-Containing Protein 28*/genetics

  • Source: Molecular biomedicine [Mol Biomed] 2024 Nov 13; Vol. 5 (1), pp. 58. Date of Electronic Publication: 2024 Nov 13.Publisher: Springer Singapore Country of Publication: Singapore NLM ID: 9918283581406676 Publication Model: Electronic Cited Medium: Internet ISSN:

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Academic Journal

A highly sensitive reporter system to monitor endogenous YAP1/TAZ activity and its application in various human cells.

  • Authors : Hikasa H; Department of Biochemistry, School of Medicine, University of Occupational and Environmental Health, Fukuoka, Japan.; Division of Cancer Genetics, Medical Institute of Bioregulation, Kyushu University, Fukuoka, Japan.

Subjects: Adaptor Proteins, Signal Transducing*/Adaptor Proteins, Signal Transducing*/Adaptor Proteins, Signal Transducing*/metabolism ; Transcription Factors*/Transcription Factors*/Transcription Factors*/metabolism ; YAP-Signaling Proteins*/YAP-Signaling Proteins*/YAP-Signaling Proteins*/metabolism

  • Source: Cancer science [Cancer Sci] 2024 Oct; Vol. 115 (10), pp. 3370-3383. Date of Electronic Publication: 2024 Aug 18.Publisher: Wiley Publishing on behalf of the Japanese Cancer Association Country of Publication: England NLM ID: 101168776 Publication Model: Print-Electronic

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Academic Journal

Cap-related modifications of RNA regulate binding to IFIT proteins.

  • Authors : Geng J; Interdisciplinary Laboratory of Molecular Biology and Biophysics, Centre of New Technologies, University of Warsaw, 02-097 Warsaw, Poland.; Chrabaszczewska M

Subjects: RNA-Binding Proteins*/RNA-Binding Proteins*/RNA-Binding Proteins*/metabolism ; RNA-Binding Proteins*/RNA-Binding Proteins*/RNA-Binding Proteins*/genetics ; Protein Binding*

  • Source: RNA (New York, N.Y.) [RNA] 2024 Sep 16; Vol. 30 (10), pp. 1292-1305. Date of Electronic Publication: 2024 Sep 16.Publisher: Cold Spring Harbor Laboratory Press Country of Publication: United States NLM ID: 9509184 Publication Model: Electronic Cited Medium:

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Editorial & Opinion

Null-type SH2B3 mutations are potential drivers in a subset of Ph-negative myeloproliferative neoplasms.

  • Authors : Zhang X; Division of Hematopathology, Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, Minnesota, USA.; Ding Y

Subjects: Myeloproliferative Disorders*/Myeloproliferative Disorders*/Myeloproliferative Disorders*/genetics ; Mutation* ; Adaptor Proteins, Signal Transducing*/Adaptor Proteins, Signal Transducing*/Adaptor Proteins, Signal Transducing*/genetics

  • Source: American journal of hematology [Am J Hematol] 2024 Sep; Vol. 99 (9), pp. 1841-1844. Date of Electronic Publication: 2024 Jun 25.Publisher: Wiley-Blackwell Country of Publication: United States NLM ID: 7610369 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Multiple endocrine defects in adult-onset Sprouty1/2/4 triple knockout mice.

  • Authors : Altés G; Developmental and Oncogenic Signaling Group, Edifici Biomedicina I, Lab 2.8, Department of Experimental Medicine, Universitat de Lleida/Institut de Recerca Biomèdica de Lleida, Rovira Roure, 80, 25198, Lleida, Spain.; Olomí A

Subjects: Mice, Knockout* ; Membrane Proteins*/Membrane Proteins*/Membrane Proteins*/genetics ; Membrane Proteins*/Membrane Proteins*/Membrane Proteins*/metabolism

  • Source: Scientific reports [Sci Rep] 2024 Aug 22; Vol. 14 (1), pp. 19479. Date of Electronic Publication: 2024 Aug 22.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN:

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Academic Journal

[Clinical and genetic analysis of three children with Legius syndrome due to variants of SPRED1 gene].

  • Authors : Wang X; Department of Endocrinology, Genetics and Metabolism, Children's Hospital Affiliated to Zhengzhou University, Children's Hospital of Henan Province, Zhengzhou Children's Hospital, Zhengzhou, Henan 450053, China, Zhengzhou, Henan 450053, China. .; Zhang Y

Subjects: Adaptor Proteins, Signal Transducing*/Adaptor Proteins, Signal Transducing*/Adaptor Proteins, Signal Transducing*/genetics ; Intracellular Signaling Peptides and Proteins*/Intracellular Signaling Peptides and Proteins*/Intracellular Signaling Peptides and Proteins*/genetics; Humans Legius syndrome

  • Source: Zhonghua yi xue yi chuan xue za zhi = Zhonghua yixue yichuanxue zazhi = Chinese journal of medical genetics [Zhonghua Yi Xue Yi Chuan Xue Za Zhi] 2024 Aug 10; Vol. 41 (8), pp. 941-946.Publisher: Sichuan University Country of Publication: China NLM ID: 9425197 Publication Model: Print Cited Medium: Print ISSN: 1003-9406 (Print)

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Academic Journal

[Genetic Variation of SH2B3 in Patients with Myeloid Neoplasms].

  • Authors : Ma Q; Department of Hematology, Xuanwu Hospital, Capital Medical University, Beijing 100053, China.; Hu RH

Subjects: Adaptor Proteins, Signal Transducing*/Adaptor Proteins, Signal Transducing*/Adaptor Proteins, Signal Transducing*/genetics ; Mutation* ; Intracellular Signaling Peptides and Proteins*/Intracellular Signaling Peptides and Proteins*/Intracellular Signaling Peptides and Proteins*/genetics

  • Source: Zhongguo shi yan xue ye xue za zhi [Zhongguo Shi Yan Xue Ye Xue Za Zhi] 2024 Aug; Vol. 32 (4), pp. 1186-1190.Publisher: Zhongguo shi yan xue za zhi she Country of Publication: China NLM ID: 101084424 Publication Model: Print Cited Medium: Print ISSN:

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  • 1-10 of  319 results for ""Intracellular Signaling Peptides and Proteins genetics""