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Academic Journal

Pharmacology of Adenosine A 1 Receptor Agonist in a Humanized Esterase Mouse Seizure Model Following Soman Intoxication.

  • Authors : Shih TM; Neuroscience Department, Medical Toxicology Research Division, U.S. Army Medical Research Institute of Chemical Defense, Aberdeen Proving Ground, MD, 21010-5400, USA. .; Munoz C

Subjects: Soman*/Soman*/Soman*/toxicity ; Seizures*/Seizures*/Seizures*/chemically induced ; Seizures*/Seizures*/Seizures*/drug therapy

  • Source: Neurotoxicity research [Neurotox Res] 2024 Sep 04; Vol. 42 (5), pp. 41. Date of Electronic Publication: 2024 Sep 04.Publisher: Springer Country of Publication: United States NLM ID: 100929017 Publication Model: Electronic Cited Medium: Internet ISSN: 1476-3524

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Academic Journal

Learning and memory function preserved by delayed A 1 adenosine receptor agonist treatment following soman intoxication in rats and a humanized esterase mouse model.

  • Authors : Harkins J; Medical Toxicology Research Division, U.S. Army Medical Research Institute of Chemical Defense, 8350 Ricketts Point Road, Aberdeen Proving Ground, MD, 21010-5400, USA. Electronic address: .; Langston J

Subjects: Soman*/Soman*/Soman*/toxicity ; Adenosine A1 Receptor Agonists*/Adenosine A1 Receptor Agonists*/Adenosine A1 Receptor Agonists*/pharmacology ; Acetylcholinesterase*/Acetylcholinesterase*/Acetylcholinesterase*/metabolism

  • Source: Neuropharmacology [Neuropharmacology] 2024 Aug 01; Vol. 253, pp. 109983. Date of Electronic Publication: 2024 May 03.Publisher: Pergamon Press Country of Publication: England NLM ID: 0236217 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Memantine and Its Combination with Acetylcholinesterase Inhibitors in Pharmacological Pretreatment of Soman Poisoning in Mice.

  • Authors : Kassa J; Department of Toxicology and Military Pharmacy, Faculty of Military Health Sciences, University of Defence, Trebesska 1575, 500 01, Hradec Králové, Czech Republic.; Karasova JZ

Subjects: Acetylcholinesterase/Acetylcholinesterase/Acetylcholinesterase/*metabolism ; Cholinesterase Inhibitors/Cholinesterase Inhibitors/Cholinesterase Inhibitors/*administration & dosage ; Donepezil/Donepezil/Donepezil/*administration & dosage

  • Source: Neurotoxicity research [Neurotox Res] 2021 Oct; Vol. 39 (5), pp. 1487-1494. Date of Electronic Publication: 2021 Jul 22.Publisher: Springer Country of Publication: United States NLM ID: 100929017 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Novel Genetically Modified Mouse Model to Assess Soman-Induced Toxicity and Medical Countermeasure Efficacy: Human Acetylcholinesterase Knock-in Serum Carboxylesterase Knockout Mice.

  • Authors : Marrero-Rosado BM; Medical Toxicology Research Division, US Army Medical Research Institute of Chemical Defense, Aberdeen Proving Ground, MD 21010, USA.; Stone MF

Subjects: Disease Models, Animal* ; Medical Countermeasures*; Acetylcholinesterase/Acetylcholinesterase/Acetylcholinesterase/*metabolism

  • Source: International journal of molecular sciences [Int J Mol Sci] 2021 Feb 14; Vol. 22 (4). Date of Electronic Publication: 2021 Feb 14.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067

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Academic Journal

Mechanisms of acetylcholinesterase protection against sarin and soman by adenosine A 1 receptor agonist N 6 -cyclopentyladenosine.

  • Authors : Beste A; US Army Research Laboratory, Deer Creek Loop, Aberdeen Proving Ground, MD 21005-5069, USA. Electronic address: .; Taylor DE

Subjects: Acetylcholinesterase/Acetylcholinesterase/Acetylcholinesterase/*metabolism ; Adenosine/Adenosine/Adenosine/*analogs & derivatives ; Adenosine A1 Receptor Agonists/Adenosine A1 Receptor Agonists/Adenosine A1 Receptor Agonists/*metabolism

  • Source: Computational biology and chemistry [Comput Biol Chem] 2018 Aug; Vol. 75, pp. 74-81. Date of Electronic Publication: 2018 May 07.Publisher: Elsevier Country of Publication: England NLM ID: 101157394 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-928X

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Academic Journal

Use of Hupresin To Capture Red Blood Cell Acetylcholinesterase for Detection of Soman Exposure.

  • Authors : Onder S; Hacettepe University , Department of Biochemistry, School of Pharmacy, 06100 Ankara, Turkey.; Eppley Institute, University of Nebraska Medical Center , Omaha, Nebraska 68198, United States.

Subjects: Acetylcholinesterase/Acetylcholinesterase/Acetylcholinesterase/*analysis ; Chromatography, Affinity/Chromatography, Affinity/Chromatography, Affinity/*methods ; Nerve Agents/Nerve Agents/Nerve Agents/*analysis

  • Source: Analytical chemistry [Anal Chem] 2018 Jan 02; Vol. 90 (1), pp. 974-979. Date of Electronic Publication: 2017 Dec 13.Publisher: American Chemical Society Country of Publication: United States NLM ID: 0370536 Publication Model: Print-Electronic Cited Medium: Internet

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Academic Journal

Synthesis and in vitro assessment of the reactivation profile of clinically available oximes on the acetylcholinesterase model inhibited by A-230 nerve agent surrogate.

  • Authors : Bernardo LB; Instituto Militar de Engenharia (IME), Praça General Tibúrcio 80, Rio de Janeiro, RJ, 22290-270, Brazil. .; Instituto de Defesa Química, Biológica, Radiológica e Nuclear (IDQBRN), Centro Tecnológico do Exército (CTEx), Avenida das Américas 28705, Área 4, Rio de Janeiro, RJ, 23020-470, Brazil. .

Subjects: Oximes*/Oximes*/Oximes*/pharmacology ; Acetylcholinesterase*/Acetylcholinesterase*/Acetylcholinesterase*/metabolism ; Cholinesterase Reactivators*/Cholinesterase Reactivators*/Cholinesterase Reactivators*/pharmacology

  • Source: Archives of toxicology [Arch Toxicol] 2024 Oct; Vol. 98 (10), pp. 3397-3407. Date of Electronic Publication: 2024 Jul 14.Publisher: Springer-Verlag Country of Publication: Germany NLM ID: 0417615 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

A first principles investigation of aging processes in soman conjugated AChE.

  • Authors : Chandar NB; Analytical Discipline and Centralized Instrument Facility, Central Salt and Marine Chemicals Research Institute Council of Scientific and Industrial Research, Bhavnagar, Gujarat 364 002, India.; Ganguly B

Subjects: Aging*/Aging*/Aging*/drug effects; Acetylcholinesterase/Acetylcholinesterase/Acetylcholinesterase/*metabolism ; Chemical Warfare Agents/Chemical Warfare Agents/Chemical Warfare Agents/*chemistry

  • Source: Chemico-biological interactions [Chem Biol Interact] 2013 Aug 25; Vol. 204 (3), pp. 185-90. Date of Electronic Publication: 2013 Jun 05.Publisher: Elsevier Country of Publication: Ireland NLM ID: 0227276 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1872-7786

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Academic Journal

Catalytic Soman Scavenging by the Y337A/F338A Acetylcholinesterase Mutant Assisted with Novel Site-Directed Aldoximes.

  • Authors : Kovarik Z; †Institute for Medical Research and Occupational Health, Ksaverska cesta 2, HR-10000 Zagreb, Croatia.; Maček Hrvat N

Subjects: Acetylcholinesterase/Acetylcholinesterase/Acetylcholinesterase/*genetics ; Acetylcholinesterase/Acetylcholinesterase/Acetylcholinesterase/*pharmacology ; Chemical Warfare Agents/Chemical Warfare Agents/Chemical Warfare Agents/*toxicity

  • Source: Chemical research in toxicology [Chem Res Toxicol] 2015 May 18; Vol. 28 (5), pp. 1036-44. Date of Electronic Publication: 2015 Apr 16.Publisher: American Chemical Society Country of Publication: United States NLM ID: 8807448 Publication Model: Print-Electronic Cited Medium: Internet

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A wrench in the works of human acetylcholinesterase: soman induced conformational changes revealed by molecular dynamics simulations.

  • Authors : Bennion BJ; Biosciences and Biotechnology Division, Lawrence Livermore National Laboratory, 7000 East Ave, Livermore CA, United States of America.; Essiz SG

Subjects: Acetylcholinesterase/Acetylcholinesterase/Acetylcholinesterase/*chemistry ; Cholinesterase Inhibitors/Cholinesterase Inhibitors/Cholinesterase Inhibitors/*pharmacology ; Protein Conformation/Protein Conformation/Protein Conformation/*drug effects

  • Source: PloS one [PLoS One] 2015 Apr 13; Vol. 10 (4), pp. e0121092. Date of Electronic Publication: 2015 Apr 13 (Print Publication: 2015).Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: eCollection Cited Medium: Internet

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  • 1-10 of  1,322 results for ""Soman""