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Academic Journal

Fragment-based design and synthesis of coumarin-based thiazoles as dual c-MET/STAT-3 inhibitors for potential antitumor agents.

  • Authors : Naguib BH; Pharmaceutical Organic Chemistry Department, Faculty of Pharmacy, Cairo University, Cairo, Egypt; Department of Pharmaceutical Chemistry, Faculty of Pharmacy, The British University in Egypt, El-Sherouk City, Cairo 11837, Egypt.

Subjects: Coumarins*/Coumarins*/Coumarins*/pharmacology ; Coumarins*/Coumarins*/Coumarins*/chemistry ; Coumarins*/Coumarins*/Coumarins*/chemical synthesis

  • Source: Bioorganic chemistry [Bioorg Chem] 2024 Oct; Vol. 151, pp. 107682. Date of Electronic Publication: 2024 Aug 06.Publisher: Elsevier Country of Publication: United States NLM ID: 1303703 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Novel imidazo[2,1-b]thiazoles and imidazo[1,2-a]pyridines tethered with indolinone motif as VEGFR-2 inhibitors and apoptotic inducers: Design, synthesis and biological evaluations.

  • Authors : Elkotamy MS; Pharmaceutical Chemistry Department, Faculty of Pharmacy, Egyptian-Russian University, Badr City 11829, Cairo, Egypt. Electronic address: .; Elgohary MK

Subjects: Vascular Endothelial Growth Factor Receptor-2*/Vascular Endothelial Growth Factor Receptor-2*/Vascular Endothelial Growth Factor Receptor-2*/antagonists & inhibitors ; Vascular Endothelial Growth Factor Receptor-2*/Vascular Endothelial Growth Factor Receptor-2*/Vascular Endothelial Growth Factor Receptor-2*/metabolism ; Pyridines*/Pyridines*/Pyridines*/chemistry

  • Source: Bioorganic chemistry [Bioorg Chem] 2024 Oct; Vol. 151, pp. 107644. Date of Electronic Publication: 2024 Jul 15.Publisher: Elsevier Country of Publication: United States NLM ID: 1303703 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Synthesis of novel thiazoles bearing lupeol derivatives as potent anticancer and anti-inflammatory agents.

  • Authors : Narendar K; Centre for Natural Products & Traditional Knowledge, CSIR-Indian Institute of Chemical Technology, Hyderabad, 500 007, India.; Academy of Scientific and Innovative Research (AcSIR), Ghaziabad, 201002, India.

Subjects: Pentacyclic Triterpenes*/Pentacyclic Triterpenes*/Pentacyclic Triterpenes*/pharmacology ; Pentacyclic Triterpenes*/Pentacyclic Triterpenes*/Pentacyclic Triterpenes*/chemistry ; Anti-Inflammatory Agents*/Anti-Inflammatory Agents*/Anti-Inflammatory Agents*/pharmacology

  • Source: Natural product research [Nat Prod Res] 2024 Jul; Vol. 38 (13), pp. 2207-2214. Date of Electronic Publication: 2023 Jan 24.Publisher: Taylor & Francis Health Sciences Country of Publication: England NLM ID: 101167924 Publication Model: Print-Electronic Cited Medium: Internet

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Academic Journal

Design, synthesis and neuraminidase inhibitory activity of 4-methyl-5-(3-phenylacryloyl) thiazoles.

  • Authors : Liu YY; College of Chemistry and Chemical Engineering, Hunan University, Changsha, 410082, China.; Yi YJ

Subjects: Neuraminidase*/Neuraminidase*/Neuraminidase*/antagonists & inhibitors ; Drug Design* ; Molecular Docking Simulation*

  • Source: Molecular diversity [Mol Divers] 2024 Jun; Vol. 28 (3), pp. 1129-1140. Date of Electronic Publication: 2023 Mar 23.Publisher: ESCOM Science Publishers Country of Publication: Netherlands NLM ID: 9516534 Publication Model: Print-Electronic Cited Medium: Internet

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Academic Journal

Fungicidal Activity of New Pyrrolo[2,3- d ]thiazoles and Their Potential Action on the Tryptophan Metabolic Pathway and Wax Biosynthesis.

  • Authors : Zhang Y; State Key Laboratory of Elemento-Organic Chemistry, College of Chemistry, Nankai University, Tianjin 300071, P. R. China.; Frontiers Science Center for New Organic Matter, College of Chemistry, Nankai University, No. 94, Weijin Road, Nankai District, Tianjin 300071, P. R. China.

Subjects: Fungicides, Industrial*/Fungicides, Industrial*/Fungicides, Industrial*/pharmacology ; Fungicides, Industrial*/Fungicides, Industrial*/Fungicides, Industrial*/chemistry ; Fungicides, Industrial*/Fungicides, Industrial*/Fungicides, Industrial*/chemical synthesis Botrytis cinerea; Rhizoctonia solani

  • Source: Journal of agricultural and food chemistry [J Agric Food Chem] 2024 May 29; Vol. 72 (21), pp. 11990-12002. Date of Electronic Publication: 2024 May 17.Publisher: American Chemical Society Country of Publication: United States NLM ID: 0374755 Publication Model: Print-Electronic Cited Medium: Internet

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Academic Journal

Discovery and Mechanistic Studies of Dual-Target Hits for Carbonic Anhydrase IX and VEGFR-2 as Potential Agents for Solid Tumors: X-ray, In Vitro , In Vivo , and In Silico Investigations of Coumarin-Based Thiazoles.

  • Authors : Hefny SM; Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Tanta University, Tanta 31527, Egypt.; El-Moselhy TF

Subjects: Coumarins*/Coumarins*/Coumarins*/chemistry ; Coumarins*/Coumarins*/Coumarins*/pharmacology ; Coumarins*/Coumarins*/Coumarins*/chemical synthesis

  • Source: Journal of medicinal chemistry [J Med Chem] 2024 May 09; Vol. 67 (9), pp. 7406-7430. Date of Electronic Publication: 2024 Apr 20.Publisher: American Chemical Society Country of Publication: United States NLM ID: 9716531 Publication Model: Print-Electronic Cited Medium: Internet

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Academic Journal

Synthesis, DPPH Radical Scavenging, Cytotoxic Activity, and Apoptosis Induction Efficacy of Novel Thiazoles and Bis-thiazoles.

  • Authors : Negm A; Department of Chemistry, College of Science, King Faisal University, Al-Ahsa, 31982, Saudi Arabia.; Chemistry Department, Faculty of Science, Mansoura University, Mansoura, 35516, Egypt.

Subjects: Thiazoles*/Thiazoles*/Thiazoles*/pharmacology ; Thiazoles*/Thiazoles*/Thiazoles*/chemical synthesis ; Apoptosis*/Apoptosis*/Apoptosis*/drug effects

  • Source: Current organic synthesis [Curr Org Synth] 2024; Vol. 21 (8), pp. 1081-1090.Publisher: Bentham Science Publishers Country of Publication: United Arab Emirates NLM ID: 101208457 Publication Model: Print Cited Medium: Internet

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Academic Journal

Novel Synthesized Benzophenone Thiazole Hybrids Exhibited Ex Vivo and In Silico Anti-Inflammatory Activity.

  • Authors : Leão LPMO; Institute of Chemistry, Federal University of Alfenas, Alfenas, Minas Gerais, Brazil.; Neto AK

Subjects: Benzophenones*/Benzophenones*/Benzophenones*/chemistry ; Benzophenones*/Benzophenones*/Benzophenones*/pharmacology ; Benzophenones*/Benzophenones*/Benzophenones*/chemical synthesis

  • Source: Chemical biology & drug design [Chem Biol Drug Des] 2024 Oct; Vol. 104 (4), pp. e14634.Publisher: Wiley-Blackwell Country of Publication: England NLM ID: 101262549 Publication Model: Print Cited Medium: Internet ISSN: 1747-0285

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Academic Journal

Directed Design, Screening and Antiglycation Activity for 3-Substituted Thiazolium Derivatives, New Analogs of Alagebrium.

  • Authors : Zhukovskaya ON; Institute of Physical and Organic Chemistry, Southern Federal University, Russian Federation, Rostov-on-Don, Russia.; Kolodina AA

Subjects: Thiazoles*/Thiazoles*/Thiazoles*/chemistry ; Thiazoles*/Thiazoles*/Thiazoles*/pharmacology ; Thiazoles*/Thiazoles*/Thiazoles*/chemical synthesis

  • Source: Chemical biology & drug design [Chem Biol Drug Des] 2024 Oct; Vol. 104 (4), pp. e14630.Publisher: Wiley-Blackwell Country of Publication: England NLM ID: 101262549 Publication Model: Print Cited Medium: Internet ISSN: 1747-0285

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Academic Journal

Evaluation of thiopyrano[2,3-d]thiazole derivatives as potential anticonvulsant agents.

  • Authors : Davydov E; Department of Pharmacology and Pharmacotherapy, National Pharmaceutical University, Kharkiv, Ukraine.; Hoidyk M

Subjects: Anticonvulsants*/Anticonvulsants*/Anticonvulsants*/pharmacology ; Anticonvulsants*/Anticonvulsants*/Anticonvulsants*/chemical synthesis ; Anticonvulsants*/Anticonvulsants*/Anticonvulsants*/chemistry

  • Source: Archiv der Pharmazie [Arch Pharm (Weinheim)] 2024 Oct; Vol. 357 (10), pp. e2400357. Date of Electronic Publication: 2024 Jun 29.Publisher: Wiley-VCH Verlag GmbH & Co. KGaA Country of Publication: Germany NLM ID: 0330167 Publication Model: Print-Electronic Cited Medium: Internet

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  • 1-10 of  56,017 results for ""Thiazoles""