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Academic Journal

Research Progress on Plant-Derived Cardenolides (2010-2023).

  • Authors : He YL; Research Institute, Lanzhou Jiaotong University, Lanzhou, 730070, People's Republic of China.; State Key Laboratory of Applied Organic Chemistry, College of Chemistry and Chemical Engineering, Lanzhou University, Lanzhou, 730000, People's Republic of China.

Subjects: Cardenolides*/Cardenolides*/Cardenolides*/chemistry ; Cardenolides*/Cardenolides*/Cardenolides*/pharmacology ; Cardenolides*/Cardenolides*/Cardenolides*/isolation & purification

  • Source: Chemistry & biodiversity [Chem Biodivers] 2024 Dec; Vol. 21 (12), pp. e202401460. Date of Electronic Publication: 2024 Oct 18.Publisher: Verlag Helvetica Chimica Acta Country of Publication: Switzerland NLM ID: 101197449 Publication Model: Print-Electronic Cited Medium:

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Academic Journal

Identification of steroidal cardenolides from Calotropis procera as novel HIV-1 PR inhibitors: A molecular docking & molecular dynamics simulation study.

  • Authors : Swapna K; Department of Zoology, Kakatiya University, Hanamkonda, Warangal, Telangana, India.; Srujana M

Subjects: Calotropis*/Calotropis*/Calotropis*/chemistry ; Molecular Docking Simulation* ; HIV-1*/HIV-1*/HIV-1*/drug effects

  • Source: The Indian journal of medical research [Indian J Med Res] 2024 Jul; Vol. 160 (1), pp. 78-86.Publisher: Medknow Country of Publication: India NLM ID: 0374701 Publication Model: Print Cited Medium: Internet ISSN: 0971-5916 (Print)

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Academic Journal

Addressing the Evolution of Cardenolide Formation in Iridoid-Synthesizing Plants: Site-Directed Mutagenesis of PRISEs (Progesterone-5β-Reductase/Iridoid Synthase-like Enzymes) of Plantago Species.

  • Authors : Dorfner M; Friedrich-Alexander-Universität Erlangen-Nürnberg, Department of Biology, Pharmaceutical Biology, Staudtstraße 5, 91058 Erlangen, Germany.; Klein J

Subjects: Mutagenesis, Site-Directed* ; Plantago*/Plantago*/Plantago*/genetics ; Plantago*/Plantago*/Plantago*/metabolism

  • Source: Molecules (Basel, Switzerland) [Molecules] 2024 Dec 07; Vol. 29 (23). Date of Electronic Publication: 2024 Dec 07.Publisher: MDPI Country of Publication: Switzerland NLM ID: 100964009 Publication Model: Electronic Cited Medium: Internet ISSN: 1420-3049

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Academic Journal

Potent Nitrogen-containing Milkweed Toxins are Differentially Regulated by Soil Nitrogen and Herbivore-induced Defense.

  • Authors : Agrawal AA; Department of Ecology and Evolutionary Biology, Cornell University, Ithaca, NY, 14853, USA. .; Department of Entomology, Cornell University, Ithaca, NY, 14853, USA. .

Subjects: Asclepias*/Asclepias*/Asclepias*/chemistry ; Asclepias*/Asclepias*/Asclepias*/metabolism ; Butterflies*/Butterflies*/Butterflies*/physiology

  • Source: Journal of chemical ecology [J Chem Ecol] 2024 Nov; Vol. 50 (11), pp. 725-737. Date of Electronic Publication: 2024 Oct 29.Publisher: Springer Country of Publication: United States NLM ID: 7505563 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Bioassay-Guided Fractionation and Biological Activity of Cardenolides from Streptocaulon juventas.

  • Authors : Xu Y; Department of Biomedical Sciences, Joan C. Edwards School of Medicine, Marshall University, Huntington, WV, USA.; Xu J

Subjects: Cardenolides*/Cardenolides*/Cardenolides*/pharmacology ; Cardiac Glycosides*/Cardiac Glycosides*/Cardiac Glycosides*/chemistry; Male

  • Source: Planta medica [Planta Med] 2023 Dec; Vol. 89 (15), pp. 1444-1456. Date of Electronic Publication: 2023 Sep 14.Publisher: George Thieme Country of Publication: Germany NLM ID: 0066751 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Thevetia thevetioides Cardenolide and Related Cardiac Glycoside Profile in Mature and Immature Seeds by High-Resolution Thin-Layer Chromatography (HPTLC) and Quadrupole Time of Flight-Tandem Mass Spectrometry (Q-TOF MS/MS) Reveals Insights of the Cardenolide Biosynthetic Pathway.

  • Authors : Vázquez-Martínez J; Departamento de Ingeniería Química, Tecnológico Nacional de México/ITS Irapuato, Silao-Irapuato km 12.5 El Copal, Irapuato 36821, GTO, Mexico.; Bravo-Villa P

Subjects: Seeds*/Seeds*/Seeds*/chemistry ; Seeds*/Seeds*/Seeds*/metabolism ; Cardenolides*/Cardenolides*/Cardenolides*/metabolism

  • Source: Molecules (Basel, Switzerland) [Molecules] 2024 Aug 28; Vol. 29 (17). Date of Electronic Publication: 2024 Aug 28.Publisher: MDPI Country of Publication: Switzerland NLM ID: 100964009 Publication Model: Electronic Cited Medium: Internet ISSN: 1420-3049

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Academic Journal

Cardenolide glycosides sensitize gefitinib-induced apoptosis in non-small cell lung cancer: inhibition of Na + /K + -ATPase serving as a switch-on mechanism.

  • Authors : Du CM; School of Pharmacy, National Taiwan University, No. 33, Linsen S. Rd., Zhongzheng Dist, Taipei, 100, Taiwan.; Leu WJ

Subjects: Carcinoma, Non-Small-Cell Lung*/Carcinoma, Non-Small-Cell Lung*/Carcinoma, Non-Small-Cell Lung*/drug therapy ; Carcinoma, Non-Small-Cell Lung*/Carcinoma, Non-Small-Cell Lung*/Carcinoma, Non-Small-Cell Lung*/pathology ; Carcinoma, Non-Small-Cell Lung*/Carcinoma, Non-Small-Cell Lung*/Carcinoma, Non-Small-Cell Lung*/metabolism

  • Source: Naunyn-Schmiedeberg's archives of pharmacology [Naunyn Schmiedebergs Arch Pharmacol] 2024 Sep; Vol. 397 (9), pp. 6533-6550. Date of Electronic Publication: 2024 Mar 07.Publisher: Springer Verlag Country of Publication: Germany NLM ID: 0326264 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Convergence and Divergence among Herbivorous Insects Specialized on Toxic Plants: Revealing Syndromes among the Cardenolide Feeders across the Insect Tree of Life.

Subjects: Herbivory* ; Insecta*/Insecta*/Insecta*/genetics ; Biological Evolution*

  • Source: The American naturalist [Am Nat] 2024 Sep; Vol. 204 (3), pp. 201-220. Date of Electronic Publication: 2024 Jul 15.Publisher: University of Chicago Press Country of Publication: United States NLM ID: 2984688R Publication Model: Print-Electronic Cited Medium: Internet

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Academic Journal

Oleandrin enhances radiotherapy sensitivity in lung cancer by inhibiting the ATM/ATR-mediated DNA damage response.

  • Authors : Wu Q; Department of Integrated Chinese and Western Medicine, Zhejiang Cancer Hospital, Hangzhou, Zhejiang, China.; Hangzhou Institute of Medicine (HIM), Chinese Academy of Sciences, Hangzhou, Zhejiang, China.

Subjects: Ataxia Telangiectasia Mutated Proteins*/Ataxia Telangiectasia Mutated Proteins*/Ataxia Telangiectasia Mutated Proteins*/metabolism ; Lung Neoplasms*/Lung Neoplasms*/Lung Neoplasms*/drug therapy ; Lung Neoplasms*/Lung Neoplasms*/Lung Neoplasms*/radiotherapy

  • Source: Phytotherapy research : PTR [Phytother Res] 2024 Aug; Vol. 38 (8), pp. 4151-4167. Date of Electronic Publication: 2024 Jun 22.Publisher: Wiley Country of Publication: England NLM ID: 8904486 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1099-1573

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Academic Journal

Quantification of plant cardenolides by HPLC, measurement of Na + /K + -ATPase inhibition activity, and characterization of target enzymes.

  • Authors : Petschenka G; Institute of Phytomedicine, University of Hohenheim, Stuttgart, Germany.; Züst T

Subjects: Cardenolides*/Cardenolides*/Cardenolides*/pharmacology ; Cardiac Glycosides*/Cardiac Glycosides*/Cardiac Glycosides*/pharmacology; Animals

  • Source: Methods in enzymology [Methods Enzymol] 2023; Vol. 680, pp. 275-302. Date of Electronic Publication: 2022 Sep 07.Publisher: Academic Press Country of Publication: United States NLM ID: 0212271 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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