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Academic Journal

Increased coproporphyrin serum levels in healthy volunteers treated with the cholesterol uptake inhibitor ezetimibe.

  • Authors : Kinzi J; Biopharmacy, Department of Pharmaceutical Sciences, University of Basel, Basel, Switzerland.; Grube M

Subjects: Ezetimibe*/Ezetimibe*/Ezetimibe*/administration & dosage ; Ezetimibe*/Ezetimibe*/Ezetimibe*/pharmacology ; Ezetimibe*/Ezetimibe*/Ezetimibe*/pharmacokinetics

  • Source: Clinical and translational science [Clin Transl Sci] 2024 Oct; Vol. 17 (10), pp. e70041.Publisher: WileyBlackwell Pub Country of Publication: United States NLM ID: 101474067 Publication Model: Print Cited Medium:

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Toward pharmacogenetic SLCO1B1-guided dosing of methotrexate in arthritis using a murine Slco1b2 knockout model.

  • Authors : Taylor ZL; Department of Pharmacology and Systems Physiology, University of Cincinnati, Cincinnati, Ohio, USA.; Division of Research in Patient Services, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, USA.

Subjects: Liver-Specific Organic Anion Transporter 1* ; Mice, Knockout* ; Pharmacogenomic Testing*

  • Source: Clinical and translational science [Clin Transl Sci] 2021 Nov; Vol. 14 (6), pp. 2267-2277. Date of Electronic Publication: 2021 Jun 30.Publisher: WileyBlackwell Pub Country of Publication: United States NLM ID: 101474067 Publication Model: Print-Electronic

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Relationship of hemoglobin level and plasma coproporphyrin-I concentrations as an endogenous probe for phenotyping OATP1B.

  • Authors : Suzuki Y; Department of Medication Use Analysis and Clinical Research, Meiji Pharmaceutical University, Kiyose, Japan.; Sasamoto Y

Subjects: Coproporphyrins/Coproporphyrins/Coproporphyrins/*blood ; Hemoglobins/Hemoglobins/Hemoglobins/*analysis ; Liver-Specific Organic Anion Transporter 1/Liver-Specific Organic Anion Transporter 1/Liver-Specific Organic Anion Transporter 1/*genetics

  • Source: Clinical and translational science [Clin Transl Sci] 2021 Jul; Vol. 14 (4), pp. 1403-1411. Date of Electronic Publication: 2021 May 07.Publisher: WileyBlackwell Pub Country of Publication: United States NLM ID: 101474067 Publication Model: Print-Electronic

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Academic Journal

Regulatory guidelines do not accurately predict tolvaptan and metabolite interactions at BCRP, OATP1B1, and OAT3 transporters.

  • Authors : Shoaf SE; Quantitative Pharmacology, Otsuka Pharmaceutical Development & Commercialization, Inc., Rockville, Maryland, USA.; Bricmont P

Subjects: ATP Binding Cassette Transporter, Subfamily G, Member 2/ATP Binding Cassette Transporter, Subfamily G, Member 2/ATP Binding Cassette Transporter, Subfamily G, Member 2/*antagonists & inhibitors ; Drug Approval/Drug Approval/Drug Approval/*statistics & numerical data ; Liver-Specific Organic Anion Transporter 1/Liver-Specific Organic Anion Transporter 1/Liver-Specific Organic Anion Transporter 1/*antagonists & inhibitors

  • Source: Clinical and translational science [Clin Transl Sci] 2021 Jul; Vol. 14 (4), pp. 1535-1542. Date of Electronic Publication: 2021 Apr 09.Publisher: WileyBlackwell Pub Country of Publication: United States NLM ID: 101474067 Publication Model: Print-Electronic

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Academic Journal

Coproporphyrin I Can Serve as an Endogenous Biomarker for OATP1B1 Inhibition: Assessment Using a Glecaprevir/Pibrentasvir Clinical Study.

  • Authors : Kalluri HV; Clinical Pharmacology and Pharmacometrics, AbbVie Inc., North Chicago, Illinois, USA.; Kikuchi R

Subjects: Benzimidazoles/Benzimidazoles/Benzimidazoles/*pharmacokinetics ; Biomarkers, Pharmacological/Biomarkers, Pharmacological/Biomarkers, Pharmacological/*blood ; Coproporphyrins/Coproporphyrins/Coproporphyrins/*blood

  • Source: Clinical and translational science [Clin Transl Sci] 2021 Jan; Vol. 14 (1), pp. 373-381. Date of Electronic Publication: 2020 Oct 24.Publisher: WileyBlackwell Pub Country of Publication: United States NLM ID: 101474067 Publication Model: Print-Electronic

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Academic Journal

Substantially Increased Plasma Coproporphyrin-I Concentrations Associated With OATP1B1*15 Allele in Japanese General Population.

  • Authors : Suzuki Y; Department of Medication Use Analysis and Clinical Research, Meiji Pharmaceutical University, Tokyo, Japan.; Sasamoto Y

Subjects: Biomarkers, Pharmacological/Biomarkers, Pharmacological/Biomarkers, Pharmacological/*blood ; Coproporphyrins/Coproporphyrins/Coproporphyrins/*blood ; Liver-Specific Organic Anion Transporter 1/Liver-Specific Organic Anion Transporter 1/Liver-Specific Organic Anion Transporter 1/*genetics

  • Source: Clinical and translational science [Clin Transl Sci] 2021 Jan; Vol. 14 (1), pp. 382-388. Date of Electronic Publication: 2020 Oct 05.Publisher: WileyBlackwell Pub Country of Publication: United States NLM ID: 101474067 Publication Model: Print-Electronic

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Genetic Diversity in Drug Transporters: Impact in African Populations.

Subjects: Pharmacogenomic Variants*; Black People/Black People/Black People/*genetics ; Drug-Related Side Effects and Adverse Reactions/Drug-Related Side Effects and Adverse Reactions/Drug-Related Side Effects and Adverse Reactions/*genetics

  • Source: Clinical and translational science [Clin Transl Sci] 2020 Sep; Vol. 13 (5), pp. 848-860. Date of Electronic Publication: 2020 Mar 31.Publisher: WileyBlackwell Pub Country of Publication: United States NLM ID: 101474067 Publication Model: Print-Electronic

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Impact of SLCO1B1 Genetic Variation on Rosuvastatin Systemic Exposure in Pediatric Hypercholesterolemia.

  • Authors : Wagner JB; Ward Family Heart Center, Children's Mercy, Kansas City, Missouri, USA.; Division of Clinical Pharmacology, Toxicology, and Therapeutic Innovation, Children's Mercy, Kansas City, Missouri, USA.

Subjects: Hypercholesterolemia/Hypercholesterolemia/Hypercholesterolemia/*drug therapy ; Liver-Specific Organic Anion Transporter 1/Liver-Specific Organic Anion Transporter 1/Liver-Specific Organic Anion Transporter 1/*genetics ; Rosuvastatin Calcium/Rosuvastatin Calcium/Rosuvastatin Calcium/*pharmacokinetics

  • Source: Clinical and translational science [Clin Transl Sci] 2020 May; Vol. 13 (3), pp. 628-637. Date of Electronic Publication: 2020 Mar 09.Publisher: WileyBlackwell Pub Country of Publication: United States NLM ID: 101474067 Publication Model: Print-Electronic

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Academic Journal

Alternative Splicing of the SLCO1B1 Gene: An Exploratory Analysis of Isoform Diversity in Pediatric Liver.

  • Authors : van Groen BD; Intensive Care and Department of Pediatric Surgery, Erasmus MC-Sophia Children's Hospital, Rotterdam, The Netherlands.; Bi C

Subjects: Alternative Splicing* ; Gene Expression Regulation, Developmental*; Liver/Liver/Liver/*metabolism

  • Source: Clinical and translational science [Clin Transl Sci] 2020 May; Vol. 13 (3), pp. 509-519. Date of Electronic Publication: 2020 Jan 09.Publisher: WileyBlackwell Pub Country of Publication: United States NLM ID: 101474067 Publication Model: Print-Electronic

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Variability in In Vitro OATP1B1/1B3 Inhibition Data: Impact of Incubation Conditions on Variability and Subsequent Drug Interaction Predictions.

  • Authors : McFeely SJ; Department of Pharmaceutics, UW Drug Interaction Solutions, University of Washington, Seattle, Washington, USA.; Ritchie TK

Subjects: Drug Evaluation, Preclinical/Drug Evaluation, Preclinical/Drug Evaluation, Preclinical/*methods ; Liver-Specific Organic Anion Transporter 1/Liver-Specific Organic Anion Transporter 1/Liver-Specific Organic Anion Transporter 1/*antagonists & inhibitors ; Solute Carrier Organic Anion Transporter Family Member 1B3/Solute Carrier Organic Anion Transporter Family Member 1B3/Solute Carrier Organic Anion Transporter Family Member 1B3/*antagonists & inhibitors

  • Source: Clinical and translational science [Clin Transl Sci] 2020 Jan; Vol. 13 (1), pp. 47-52. Date of Electronic Publication: 2019 Sep 28.Publisher: WileyBlackwell Pub Country of Publication: United States NLM ID: 101474067 Publication Model: Print-Electronic

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  • 1-10 of  27 results for ""Liver-Specific Organic Anion Transporter 1""