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Academic Journal

Caspase-1-Inhibitor AC-YVAD-CMK Inhibits Pyroptosis and Ameliorates Acute Kidney Injury in a Model of Sepsis.

  • Authors : Yang M; Department of Intensive Care Unit, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, Zhejiang Province, China 325015.; Fang JT

Subjects: Acute Kidney Injury/Acute Kidney Injury/Acute Kidney Injury/*drug therapy ; Amino Acid Chloromethyl Ketones/Amino Acid Chloromethyl Ketones/Amino Acid Chloromethyl Ketones/*pharmacology ; Caspase 1/Caspase 1/Caspase 1/*metabolism

  • Source: BioMed research international [Biomed Res Int] 2021 Jun 10; Vol. 2021, pp. 6636621. Date of Electronic Publication: 2021 Jun 10 (Print Publication: 2021).Publisher: Wiley Country of Publication: United States NLM ID: 101600173 Publication Model: eCollection Cited Medium:

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Synergistic Utilization of Necrostatin-1 and Z-VAD-FMK Efficiently Promotes the Survival of Compression-Induced Nucleus Pulposus Cells via Alleviating Mitochondrial Dysfunction.

  • Authors : Chen S; Department of Orthopaedics, The First Affiliated Hospital of Zhengzhou University, Zhengzhou 450052, China.; Tian Q

Subjects: Amino Acid Chloromethyl Ketones/Amino Acid Chloromethyl Ketones/Amino Acid Chloromethyl Ketones/*pharmacology ; Imidazoles/Imidazoles/Imidazoles/*pharmacology ; Indoles/Indoles/Indoles/*pharmacology

  • Source: BioMed research international [Biomed Res Int] 2020 Dec 08; Vol. 2020, pp. 6976317. Date of Electronic Publication: 2020 Dec 08 (Print Publication: 2020).Publisher: Wiley Country of Publication: United States NLM ID: 101600173 Publication Model: eCollection Cited Medium:

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Academic Journal

Synthesis and characterization of (18)F-labeled active site inhibited factor VII (ASIS).

  • Authors : Erlandsson M; Department of Clinical Physiology, Nuclear Medicine & PET and Cluster for Molecular Imaging, Rigshospitalet, University of Copenhagen, Denmark.; Nielsen CH

Subjects: Amino Acid Chloromethyl Ketones/Amino Acid Chloromethyl Ketones/Amino Acid Chloromethyl Ketones/*chemistry ; Factor VII/Factor VII/Factor VII/*chemistry ; Radiopharmaceuticals/Radiopharmaceuticals/Radiopharmaceuticals/*chemical synthesis

  • Source: Journal of labelled compounds & radiopharmaceuticals [J Labelled Comp Radiopharm] 2015 May 15; Vol. 58 (5), pp. 196-201. Date of Electronic Publication: 2015 Mar 27.Publisher: Wiley Country of Publication: England NLM ID: 7610510 Publication Model: Print-Electronic Cited Medium:

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Academic Journal

AC-YVAD-CMK Inhibits Pyroptosis and Improves Functional Outcome after Intracerebral Hemorrhage.

  • Authors : Lin X; Department of Neurosurgery, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou 325000, China.; Zhejiang Provincial Key Laboratory of Aging and Neurological Disorder Research, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou 325000, China.

Subjects: Amino Acid Chloromethyl Ketones/Amino Acid Chloromethyl Ketones/Amino Acid Chloromethyl Ketones/*pharmacology ; Cerebral Hemorrhage/Cerebral Hemorrhage/Cerebral Hemorrhage/*metabolism ; Neuroprotective Agents/Neuroprotective Agents/Neuroprotective Agents/*pharmacology

  • Source: BioMed research international [Biomed Res Int] 2018 Oct 16; Vol. 2018, pp. 3706047. Date of Electronic Publication: 2018 Oct 16 (Print Publication: 2018).Publisher: Wiley Country of Publication: United States NLM ID: 101600173 Publication Model: eCollection Cited Medium:

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Academic Journal

MX1013, a dipeptide caspase inhibitor with potent in vivo antiapoptotic activity.

  • Authors : Yang W; Cytovia, Inc. (a subsidiary of Maxim Pharmaceuticals, Inc.), 6650 Nancy Ridge Drive, San Diego, CA 92121, U.S.A.; Guastella J

Subjects: Amino Acid Chloromethyl Ketones/Amino Acid Chloromethyl Ketones/Amino Acid Chloromethyl Ketones/*pharmacology ; Apoptosis/Apoptosis/Apoptosis/*drug effects ; Cysteine Proteinase Inhibitors/Cysteine Proteinase Inhibitors/Cysteine Proteinase Inhibitors/*pharmacology

  • Source: British journal of pharmacology [Br J Pharmacol] 2003 Sep; Vol. 140 (2), pp. 402-12. Date of Electronic Publication: 2003 Aug 26.Publisher: Wiley Country of Publication: England NLM ID: 7502536 Publication Model: Print-Electronic Cited Medium: Print

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Academic Journal

Identification of a degrading enzyme in human serum that hydrolyzes a C-terminal core sequence of neuromedin U.

  • Authors : Takayama K; Department of Medicinal Chemistry, Tokyo University of Pharmacy and Life Sciences, Horinouchi, Hachioji, Tokyo, 192-0392, Japan.; Taguchi A

Subjects: Thrombin*/Thrombin*/Thrombin*/antagonists & inhibitors ; Thrombin*/Thrombin*/Thrombin*/chemistry; Amino Acid Chloromethyl Ketones/Amino Acid Chloromethyl Ketones/Amino Acid Chloromethyl Ketones/*chemistry

  • Source: Biopolymers [Biopolymers] 2016 Nov 04; Vol. 106 (4), pp. 440-5.Publisher: Wiley Country of Publication: United States NLM ID: 0372525 Publication Model: Print Cited Medium: Internet

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Academic Journal

Insect chymotrypsins: chloromethyl ketone inactivation and substrate specificity relative to possible coevolutional adaptation of insects and plants.

  • Authors : Lopes AR; Departamento de Bioquímica, Instituto de Química, Universidade de São Paulo, São Paulo, Brazil.; Sato PM

Subjects: Adaptation, Physiological* ; Plant Physiological Phenomena*; Amino Acid Chloromethyl Ketones/Amino Acid Chloromethyl Ketones/Amino Acid Chloromethyl Ketones/*pharmacology

  • Source: Archives of insect biochemistry and physiology [Arch Insect Biochem Physiol] 2009 Mar; Vol. 70 (3), pp. 188-203.Publisher: Wiley Country of Publication: United States NLM ID: 8501752 Publication Model: Print Cited Medium: Internet

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Academic Journal

5-fluorouracil-induced oligodendrocyte death and inhibitory effect of cycloheximide, Trolox, and Z-VAD-FMK in murine cortical culture.

  • Authors : Cho KH; Department of Neurology, Chonnam National University Medical School, Chonnam National University Research Institute of Medical Science, Gwangju, South Korea.; Choi SM

Subjects: Amino Acid Chloromethyl Ketones/Amino Acid Chloromethyl Ketones/Amino Acid Chloromethyl Ketones/*pharmacology ; Antimetabolites, Antineoplastic/Antimetabolites, Antineoplastic/Antimetabolites, Antineoplastic/*pharmacology ; Cysteine Proteinase Inhibitors/Cysteine Proteinase Inhibitors/Cysteine Proteinase Inhibitors/*pharmacology

  • Source: Cancer [Cancer] 2004 Apr 01; Vol. 100 (7), pp. 1484-90.Publisher: Wiley Country of Publication: United States NLM ID: 0374236 Publication Model: Print Cited Medium: Print

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Academic Journal

Caspase-1-inhibitor ac-YVAD-cmk reduces LPS-lethality in rats without affecting haematology or cytokine responses.

  • Authors : Mathiak G; I. Department of Surgery, University of Cologne, Cologne, Germany. ; Grass G

Subjects: Caspase Inhibitors*; Amino Acid Chloromethyl Ketones/Amino Acid Chloromethyl Ketones/Amino Acid Chloromethyl Ketones/*therapeutic use ; Endotoxemia/Endotoxemia/Endotoxemia/*prevention & control

  • Source: British journal of pharmacology [Br J Pharmacol] 2000 Oct; Vol. 131 (3), pp. 383-6.Publisher: Wiley Country of Publication: England NLM ID: 7502536 Publication Model: Print Cited Medium: Print ISSN:

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Academic Journal

Inhibition of caspase activity delays apoptosis in a transfected NS/0 myeloma cell line.

  • Authors : McKenna SL; Tumour Biology Laboratory, Department of Biochemistry, University College Cork, Lee Maltings, Prospect Row, Cork, Ireland. ; Cotter TG

Subjects: Caspase Inhibitors*; Amino Acid Chloromethyl Ketones/Amino Acid Chloromethyl Ketones/Amino Acid Chloromethyl Ketones/*pharmacology ; Apoptosis/Apoptosis/Apoptosis/*drug effects

  • Source: Biotechnology and bioengineering [Biotechnol Bioeng] 2000 Jan 20; Vol. 67 (2), pp. 165-76.Publisher: Wiley Country of Publication: United States NLM ID: 7502021 Publication Model: Print Cited Medium: Print

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  • 1-10 of  49 results for ""Amino Acid Chloromethyl Ketones""