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Academic Journal

Anti-EGFR Antibody-Drug Conjugate Carrying an Inhibitor Targeting CDK Restricts Triple-Negative Breast Cancer Growth.

  • Authors : Cheung A; Breast Cancer Now Research Unit, School of Cancer and Pharmaceutical Sciences, King's College London, Guy's Cancer Centre, London, United Kingdom.; St. John's Institute of Dermatology, School of Basic and Medical Biosciences & KHP Centre for Translational Medicine, King's College London, Guy's Hospital, London, United Kingdom.

Subjects: Immunoconjugates*/Immunoconjugates*/Immunoconjugates*/pharmacology ; Triple Negative Breast Neoplasms*/Triple Negative Breast Neoplasms*/Triple Negative Breast Neoplasms*/drug therapy ; Triple Negative Breast Neoplasms*/Triple Negative Breast Neoplasms*/Triple Negative Breast Neoplasms*/pathology

  • Source: Clinical cancer research : an official journal of the American Association for Cancer Research [Clin Cancer Res] 2024 Aug 01; Vol. 30 (15), pp. 3298-3315.Publisher: The Association Country of Publication: United States NLM ID: 9502500 Publication Model:

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Academic Journal

Bystander Effects, Pharmacokinetics, and Linker-Payload Stability of EGFR-Targeting Antibody-Drug Conjugates Losatuxizumab Vedotin and Depatux-M in Glioblastoma Models.

  • Authors : Jain S; Department of Radiation Oncology, Mayo Clinic, Rochester, Minnesota.; Griffith JI

Subjects: Glioblastoma*/Glioblastoma*/Glioblastoma*/drug therapy ; Glioblastoma*/Glioblastoma*/Glioblastoma*/pathology ; Glioblastoma*/Glioblastoma*/Glioblastoma*/metabolism

  • Source: Clinical cancer research : an official journal of the American Association for Cancer Research [Clin Cancer Res] 2024 Aug 01; Vol. 30 (15), pp. 3287-3297.Publisher: The Association Country of Publication: United States NLM ID: 9502500 Publication Model:

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Academic Journal

CDKN2A/B Homozygous Deletion Sensitizes IDH-Mutant Glioma to CDK4/6 Inhibition.

  • Authors : Nasser AM; Translational Neuro-Oncology Laboratory, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts.; Melamed L

Subjects: Cyclin-Dependent Kinase 4*/Cyclin-Dependent Kinase 4*/Cyclin-Dependent Kinase 4*/antagonists & inhibitors ; Cyclin-Dependent Kinase 4*/Cyclin-Dependent Kinase 4*/Cyclin-Dependent Kinase 4*/genetics ; Cyclin-Dependent Kinase 6*/Cyclin-Dependent Kinase 6*/Cyclin-Dependent Kinase 6*/antagonists & inhibitors

  • Source: Clinical cancer research : an official journal of the American Association for Cancer Research [Clin Cancer Res] 2024 Jul 15; Vol. 30 (14), pp. 2996-3005.Publisher: The Association Country of Publication: United States NLM ID: 9502500 Publication Model:

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Academic Journal

GD2-Targeting CAR T-cell Therapy for Patients with GD2+ Medulloblastoma.

  • Authors : Ciccone R; Department of Onco-Haematology and Cell and Gene Therapy, Bambino Gesù Children's Hospital, IRCCS, Rome, Italy.; Quintarelli C

Subjects: Medulloblastoma*/Medulloblastoma*/Medulloblastoma*/therapy ; Medulloblastoma*/Medulloblastoma*/Medulloblastoma*/immunology ; Medulloblastoma*/Medulloblastoma*/Medulloblastoma*/pathology

  • Source: Clinical cancer research : an official journal of the American Association for Cancer Research [Clin Cancer Res] 2024 Jun 03; Vol. 30 (11), pp. 2545-2557.Publisher: The Association Country of Publication: United States NLM ID: 9502500 Publication Model:

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Academic Journal

Preclinical Efficacy of a PSMA-Targeted Actinium-225 Conjugate (225Ac-Macropa-Pelgifatamab): A Targeted Alpha Therapy for Prostate Cancer.

Subjects: Actinium* ; Xenograft Model Antitumor Assays* ; Glutamate Carboxypeptidase II*/Glutamate Carboxypeptidase II*/Glutamate Carboxypeptidase II*/antagonists & inhibitors

  • Source: Clinical cancer research : an official journal of the American Association for Cancer Research [Clin Cancer Res] 2024 Jun 03; Vol. 30 (11), pp. 2531-2544.Publisher: The Association Country of Publication: United States NLM ID: 9502500 Publication Model:

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Academic Journal

Mesothelin CAR T Cells Secreting Anti-FAP/Anti-CD3 Molecules Efficiently Target Pancreatic Adenocarcinoma and its Stroma.

  • Authors : Wehrli M; Cellular Immunotherapy Program, Cancer Center, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts.; Cancer Center, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts.

Subjects: Mesothelin* ; Pancreatic Neoplasms*/Pancreatic Neoplasms*/Pancreatic Neoplasms*/immunology ; Pancreatic Neoplasms*/Pancreatic Neoplasms*/Pancreatic Neoplasms*/therapy

  • Source: Clinical cancer research : an official journal of the American Association for Cancer Research [Clin Cancer Res] 2024 May 01; Vol. 30 (9), pp. 1859-1877.Publisher: The Association Country of Publication: United States NLM ID: 9502500 Publication Model:

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Academic Journal

Molecular Subtyping Combined with Biological Pathway Analyses to Study Regorafenib Response in Clinically Relevant Mouse Models of Colorectal Cancer.

  • Authors : Lafferty A; Department of Physiology and Medical Physics, Precision Cancer Medicine Group, Royal College of Surgeons in Ireland, Dublin, Ireland.; O'Farrell AC

Subjects: Xenograft Model Antitumor Assays*; Colorectal Neoplasms/Colorectal Neoplasms/Colorectal Neoplasms/*drug therapy ; Phenylurea Compounds/Phenylurea Compounds/Phenylurea Compounds/*therapeutic use

  • Source: Clinical cancer research : an official journal of the American Association for Cancer Research [Clin Cancer Res] 2021 Nov 01; Vol. 27 (21), pp. 5979-5992. Date of Electronic Publisher: The Association Country of Publication: United States NLM ID: 9502500 Publication Model:

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Academic Journal

Patient-Derived Xenograft Engraftment and Breast Cancer Outcomes in a Prospective Neoadjuvant Study (BEAUTY).

  • Authors : Boughey JC; Department of Surgery, Mayo Clinic, Rochester, Minnesota. .; Suman VJ

Subjects: Neoadjuvant Therapy* ; Transplantation, Heterologous* ; Xenograft Model Antitumor Assays*

  • Source: Clinical cancer research : an official journal of the American Association for Cancer Research [Clin Cancer Res] 2021 Sep 01; Vol. 27 (17), pp. 4696-4699. Date of Electronic Publisher: The Association Country of Publication: United States NLM ID: 9502500 Publication Model:

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Academic Journal

The Establishment of a Fast and Safe Orthotopic Colon Cancer Model Using a Tissue Adhesive Technique.

  • Authors : Hu HT; Department of Biomedical Sciences, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea.; Department of Radiology and Research Institute of Radiology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea.

Subjects: Tissue Adhesives*; Colonic Neoplasms/Colonic Neoplasms/Colonic Neoplasms/*pathology ; Xenograft Model Antitumor Assays/Xenograft Model Antitumor Assays/Xenograft Model Antitumor Assays/*instrumentation

  • Source: Cancer research and treatment [Cancer Res Treat] 2021 Jul; Vol. 53 (3), pp. 733-743. Date of Electronic Publication: 2020 Dec 15.Publisher: The Association Country of Publication: Korea (South) NLM ID: 101155137 Publication Model:

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Academic Journal

ERCC2 Helicase Domain Mutations Confer Nucleotide Excision Repair Deficiency and Drive Cisplatin Sensitivity in Muscle-Invasive Bladder Cancer.

  • Authors : Li Q; Department of Surgery, Urology Service, Memorial Sloan Kettering Cancer Center, New York, New York. .; Department of Urology, Roswell Park Cancer Institute, Buffalo, New York.

Subjects: Mutation, Missense* ; Xenograft Model Antitumor Assays*; Antineoplastic Combined Chemotherapy Protocols/Antineoplastic Combined Chemotherapy Protocols/Antineoplastic Combined Chemotherapy Protocols/*therapeutic use

  • Source: Clinical cancer research : an official journal of the American Association for Cancer Research [Clin Cancer Res] 2019 Feb 01; Vol. 25 (3), pp. 977-988. Date of Electronic Publication: Publisher: The Association Country of Publication: United States NLM ID: 9502500 Publication Model:

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  • 1-10 of  1,980 results for ""Xenograft Model Antitumor Assays""