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Academic Journal

Bumped pomalidomide-based PROTACs.

Authors : Guo, Huijuan¹ (AUTHOR)

Subjects: *UBIQUITIN ligases; *HIGH throughput screening (Drug development); *ZINC-finger proteins

Source: Communications Chemistry. 2/26/2024, Vol. 7 Issue 1, p1-2. 2p.

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Academic Journal

Spinocerebellar ataxia type 48: last but not least.

Authors : De Michele, Giovanna (AUTHOR); Galatolo, Daniele (AUTHOR); Barghigiani, Melissa (AUTHOR)

Subjects: SPINOCEREBELLAR ataxia; UBIQUITIN ligases; SYMPTOMS

Source: Neurological Sciences. Sep2020, Vol. 41 Issue 9, p2423-2432. 10p. 2 Diagrams, 1 Chart.

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Academic Journal

E3 ubiquitin ligases in cancer stem cells: key regulators of cancer hallmarks and novel therapeutic opportunities.

Authors : Zou, Qiang^1,2 (AUTHOR); Liu, Meng^2,3 (AUTHOR); Liu, Kewei² (AUTHOR)

Subjects: *UBIQUITIN ligases; *CANCER stem cells; *SINGLE molecules

Source: Cellular Oncology (2211-3428). Jun2023, Vol. 46 Issue 3, p545-570. 26p.

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Academic Journal

TRIM37 is a new histone H2A ubiquitin ligase and breast cancer oncoprotein.

Authors : Bhatnagar, Sanchita; Chamberlain, Lynn; Zhu, Xiaochun

Subjects: HISTONES; UBIQUITIN ligases; BREAST cancer research

Source: Nature. 12/4/2014, Vol. 516 Issue 7529, p116-120. 5p. 4 Graphs.

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Academic Journal

E3 ubiquitin ligases in nasopharyngeal carcinoma and implications for therapies.

Authors : Zhou, Zijian; Zheng, Kaifeng; Zhou, Shao

Subjects: UBIQUITIN ligases; NASOPHARYNX cancer; LIGASES

Source: Journal of Molecular Medicine; Dec2023, Vol. 101 Issue 12, p1543-1565, 23p

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Academic Journal

BIK1 protein homeostasis is maintained by the interplay of different ubiquitin ligases in immune signaling.

Authors : Bai, Jiaojiao; Zhou, Yuanyuan; Sun, Jianhang

Subjects: UBIQUITIN ligases; PATTERN perception receptors; PLANT proteins

Source: Nature Communications; 8/2/2023, Vol. 14 Issue 1, p1-14, 14p

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Academic Journal

A coding-independent function of an alternative Ube3a transcript during neuronal development.

Authors : Valluy, Jeremy; Bicker, Silvia; Aksoy-Aksel, Ayla

Subjects: UBIQUITIN ligases; ANGELMAN syndrome; AUTISM spectrum disorders

Source: Nature Neuroscience. May2015, Vol. 18 Issue 5, p666-673. 8p. 6 Graphs.

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Academic Journal

Allosteric activation of the RNF146 ubiquitin ligase by a poly(ADP-ribosyl)ation signal.

Authors : DaRosa, Paul A.; Wang, Zhizhi; Jiang, Xiaomo

Subjects: UBIQUITIN ligases; ENZYME activation; UBIQUITIN-conjugating enzymes

Source: Nature. 1/8/2015, Vol. 517 Issue 7533, p223-226. 4p.

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Academic Journal

The ubiquitin ligase parkin mediates resistance to intracellular pathogens.

Authors : Manzanillo, Paolo S.; Ayres, Janelle S.; Watson, Robert O.

Subjects: UBIQUITIN ligases; PARKIN (Protein); INTRACELLULAR pathogens

Source: Nature. 9/26/2013, Vol. 501 Issue 7468, p512-516. 5p. 1 Color Photograph, 8 Graphs.

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Academic Journal

Molecular architecture and mechanism of the anaphase-promoting complex.

Authors : Chang, Leifu; Zhang, Ziguo; Yang, Jing

Subjects: UBIQUITIN ligases; ANAPHASE; CELL cycle regulation

Source: Nature. 9/18/2014, Vol. 513 Issue 7518, p388-393. 6p.

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