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Exosome-like nanoparticles from Arbutus unedo L. mitigate LPS-induced inflammation via JAK-STAT inactivation.

• Authors : Martínez Fajardo C; Instituto Botánico, Departamento de Ciencia y Tecnología Agroforestal y Genética, Universidad de Castilla-La Mancha, Campus Universitario s/n, 02071 Albacete, Spain. .; Morote L

Subjects: Lipopolysaccharides*/Lipopolysaccharides*/Lipopolysaccharides*/adverse effects ; Nanoparticles*/Nanoparticles*/Nanoparticles*/chemistry ; Exosomes*/Exosomes*/Exosomes*/metabolism

• Source: Food & function [Food Funct] 2024 Nov 11; Vol. 15 (22), pp. 11280-11290. Date of Electronic Publication: 2024 Nov 11.Publisher: Royal Society of Chemistry Country of Publication: England NLM ID: 101549033 Publication Model: Electronic Cited

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Platinum-based chemotherapy: trends in organic nanodelivery systems.

• Authors : Santos, João A. V.; Silva, Daniela; Marques, Maria Paula M.

• Source: Nanoscale; 8/21/2024, Vol. 16 Issue 31, p14640-14686, 47p

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Bound polyphenols in insoluble dietary fiber of navel orange peel modulate LPS-induced intestinal-like co-culture inflammation through CSF2-mediated NF-κB/JAK-STAT pathway.

• Authors : Xinxin Chang; Bing Zheng; Yue Guo

• Source: Food & Function; 6/7/2024, Vol. 15 Issue 11, p5942-5954, 13p

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Tofacitinib and peficitinib inhibitors of Janus kinase for autoimmune disease treatment: a quantum biochemistry approach.

• Authors : Amaral, Jackson L.; Lucredi, Naiara C.; França, Victor L. B.

• Source: Physical Chemistry Chemical Physics (PCCP); 5/7/2024, Vol. 26 Issue 17, p13420-13431, 12p

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Discovery of a dual-acting inhibitor of interleukin-1β and STATs for the treatment of inflammatory bowel disease.

• Authors : Cai, Haowei; Liu, Zhuorong; Sun, Ping

• Source: RSC Medicinal Chemistry; Jan2024, Vol. 15 Issue 1, p193-206, 14p

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Design, synthesis, and anti-hepatocellular carcinoma of thiopyrimidine/chalcone hybrids as dual STAT3/STAT5 inhibitors.

• Authors : Altwaijry, Najla; Sabour, Rehab; Ibrahim, Mona H.

• Source: RSC Medicinal Chemistry; Oct2023, Vol. 14 Issue 10, p1981-1991, 11p

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In vivo targeting of a tumor-antigen encoded DNA vaccine to dendritic cells in combination with tumor-selective chemotherapy eradicates established mouse melanoma.

• Authors : Barui, Sugata; Saha, Soumen; Venu, Yakati

• Source: Biomaterials Science (2047-4830); 9/21/2023, Vol. 11 Issue 18, p6135-6148, 14p

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Development of a sensitive biochemical assay for the detection of tofacitinib adherence.

• Authors : Church, Stephanie; Hyrich, Kimme L.; Ogungbenro, Kayode

• Source: Analytical Methods; 4/14/2023, Vol. 15 Issue 14, p1797-1801, 5p

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QbD-based fabrication of transferrin-anchored nanocarriers for targeted drug delivery to macrophages and colon cells for mucosal inflammation healing.

• Authors : Zeeshan, Mahira; Ain, Qurat Ul; Sunny, Ahad

• Source: Biomaterials Science (2047-4830); 2/21/2023, Vol. 11 Issue 4, p1373-1397, 25p

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A new amide alkaloid induces the apoptosis of human melanoma A375 cells via inhibition of the STAT3 signaling pathway.

• Authors : Wang, Ru^1,2 (AUTHOR); Yang, Bo¹ (AUTHOR); Zhang, Beibei^1,2 (AUTHOR)

Subjects: *CELLULAR signal transduction; *STAT proteins; *DACARBAZINE

• Source: New Journal of Chemistry. 1/7/2023, Vol. 47 Issue 1, p120-130. 11p.

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