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Academic Journal

Mechanistic regulation of γ-secretase by their substrates.

  • Authors : Velasco-Bolom JL; Facultad de Química, Departamento de Fisicoquímica, Universidad Nacional Autónoma de México, Mexico City 04510, Mexico. .; Domínguez L

Subjects: Alzheimer Disease*/Alzheimer Disease*/Alzheimer Disease*/metabolism ; Amyloid Precursor Protein Secretases*/Amyloid Precursor Protein Secretases*/Amyloid Precursor Protein Secretases*/metabolism; Amyloid beta-Peptides/Amyloid beta-Peptides/Amyloid beta-Peptides/metabolism

  • Source: Physical chemistry chemical physics : PCCP [Phys Chem Chem Phys] 2022 Aug 17; Vol. 24 (32), pp. 19223-19232. Date of Electronic Publication: 2022 Aug 17.Publisher: Royal Society of Chemistry Country of Publication: England NLM ID: 100888160 Publication Model: Electronic Cited

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Academic Journal

New 3,5-dimethylorsellinic acid-based meroterpenoids with BACE1 and AchE inhibitory activities from Aspergillus terreus.

  • Authors : Qi C; Hubei Key Laboratory of Natural Medicinal Chemistry and Resource Evaluation, School of Pharmacy, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, Hubei Province, People's Republic of China. .; Qiao Y

Subjects: Amyloid Precursor Protein Secretases/Amyloid Precursor Protein Secretases/Amyloid Precursor Protein Secretases/*antagonists & inhibitors ; Aspartic Acid Endopeptidases/Aspartic Acid Endopeptidases/Aspartic Acid Endopeptidases/*antagonists & inhibitors ; Aspergillus/Aspergillus/Aspergillus/*chemistry

  • Source: Organic & biomolecular chemistry [Org Biomol Chem] 2018 Nov 28; Vol. 16 (46), pp. 9046-9052.Publisher: Royal Society of Chemistry Country of Publication: England NLM ID: 101154995 Publication Model: Print Cited

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Academic Journal

Stability analysis of the ODE model representation of amyloidogenic processing in Alzheimer's disease in the presence of SORLA.

  • Authors : Alcantara JH; Department of Mathematics, De La Salle University, Manila, Philippines. .; Lao AR

Subjects: Models, Biological* ; Models, Chemical*; Amyloid Precursor Protein Secretases/Amyloid Precursor Protein Secretases/Amyloid Precursor Protein Secretases/*metabolism

  • Source: Molecular bioSystems [Mol Biosyst] 2016 Apr 26; Vol. 12 (5), pp. 1468-77.Publisher: Royal Society of Chemistry Country of Publication: England NLM ID: 101251620 Publication Model: Print Cited

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Academic Journal

Interaction mechanism exploration of HEA derivatives as BACE1 inhibitors by in silico analysis.

  • Authors : Wu Q; Key Laboratory of Marine Chemistry Theory and Technology, Ministry of Education, Ocean University of China, Qingdao, 266100, China. .; Li X

Subjects: Models, Molecular* ; Quantitative Structure-Activity Relationship*; Amyloid Precursor Protein Secretases/Amyloid Precursor Protein Secretases/Amyloid Precursor Protein Secretases/*chemistry

  • Source: Molecular bioSystems [Mol Biosyst] 2016 Apr; Vol. 12 (4), pp. 1151-65. Date of Electronic Publication: 2016 Feb 26.Publisher: Royal Society of Chemistry Country of Publication: England NLM ID: 101251620 Publication Model: Print-Electronic

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Academic Journal

Identification and molecular docking study of fish roe-derived peptides as potent BACE 1, AChE, and BChE inhibitors.

  • Authors : Yu Z; College of Food Science and Engineering, Bohai University, Jinzhou 121013, P.R. China. .; Ji H

Subjects: Fishes* ; Molecular Docking Simulation*; Amyloid Precursor Protein Secretases/Amyloid Precursor Protein Secretases/Amyloid Precursor Protein Secretases/*antagonists & inhibitors

  • Source: Food & function [Food Funct] 2020 Jul 01; Vol. 11 (7), pp. 6643-6651. Date of Electronic Publication: 2020 Jul 13.Publisher: Royal Society of Chemistry Country of Publication: England NLM ID: 101549033 Publication Model: Print-Electronic

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Academic Journal

Substrate interaction inhibits γ-secretase production of amyloid-β peptides.

  • Authors : Zhao J; Center for Biotechnology and Interdisciplinary Studies, Rensselaer Polytechnic Institute, Troy, NY 12180, USA. .; Xiao Y

Subjects: Amyloid Precursor Protein Secretases/Amyloid Precursor Protein Secretases/Amyloid Precursor Protein Secretases/*metabolism ; Amyloid beta-Peptides/Amyloid beta-Peptides/Amyloid beta-Peptides/*biosynthesis; HEK293 Cells

  • Source: Chemical communications (Cambridge, England) [Chem Commun (Camb)] 2020 Feb 27; Vol. 56 (17), pp. 2578-2581.Publisher: Royal Society of Chemistry Country of Publication: England NLM ID: 9610838 Publication Model: Print Cited Medium:

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Academic Journal

Chemometric design to explore pharmacophore features of BACE inhibitors for controlling Alzheimer's disease.

  • Authors : Hossain T; Department of Chemical Technology, University of Calcutta, 92, A.P.C. Road, Kolkata-700009, India. .; Mukherjee A

Subjects: Drug Design*; Alzheimer Disease/Alzheimer Disease/Alzheimer Disease/*drug therapy ; Amyloid Precursor Protein Secretases/Amyloid Precursor Protein Secretases/Amyloid Precursor Protein Secretases/*antagonists & inhibitors

  • Source: Molecular bioSystems [Mol Biosyst] 2015 Feb; Vol. 11 (2), pp. 549-57. Date of Electronic Publication: 2014 Dec 01.Publisher: Royal Society of Chemistry Country of Publication: England NLM ID: 101251620 Publication Model: Print-Electronic

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Academic Journal

Influence of membrane lipid composition on the structure and activity of γ-secretase.

  • Authors : Aguayo-Ortiz R; Facultad de Química, Departamento de Fisicoquímica, Universidad Nacional Autónoma de México, Mexico City, 04510, Mexico. .; Straub JE

Subjects: Amyloid Precursor Protein Secretases/Amyloid Precursor Protein Secretases/Amyloid Precursor Protein Secretases/*chemistry ; Amyloid Precursor Protein Secretases/Amyloid Precursor Protein Secretases/Amyloid Precursor Protein Secretases/*metabolism ; Membrane Lipids/Membrane Lipids/Membrane Lipids/*chemistry

  • Source: Physical chemistry chemical physics : PCCP [Phys Chem Chem Phys] 2018 Nov 07; Vol. 20 (43), pp. 27294-27304.Publisher: Royal Society of Chemistry Country of Publication: England NLM ID: 100888160 Publication Model: Print Cited

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Academic Journal

Small molecule microarray-facilitated screening of affinity-based probes (AfBPs) for gamma-secretase.

  • Authors : Shi H; Department of Chemistry, National University of Singapore, 3 Science Drive 3, Singapore 117543, Singapore.; Liu K

Subjects: Amyloid Precursor Protein Secretases/Amyloid Precursor Protein Secretases/Amyloid Precursor Protein Secretases/*antagonists & inhibitors ; Protease Inhibitors/Protease Inhibitors/Protease Inhibitors/*chemistry; Amyloid Precursor Protein Secretases/Amyloid Precursor Protein Secretases/Amyloid Precursor Protein Secretases/metabolism

  • Source: Chemical communications (Cambridge, England) [Chem Commun (Camb)] 2009 Sep 07 (33), pp. 5030-2. Date of Electronic Publication: 2009 Jul 14.Publisher: Royal Society of Chemistry Country of Publication: England NLM ID: 9610838 Publication Model: Print-Electronic

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Academic Journal

A peptide-WS 2 nanosheet based biosensing platform for determination of β-secretase and screening of its inhibitors.

  • Authors : Zuo X; State Key Laboratory of Applied Organic Chemistry, Lanzhou University, Lanzhou 730000, China. .; Dai H

Subjects: Biosensing Techniques* ; Nanostructures*; Amyloid Precursor Protein Secretases/Amyloid Precursor Protein Secretases/Amyloid Precursor Protein Secretases/*analysis

  • Source: The Analyst [Analyst] 2018 Sep 24; Vol. 143 (19), pp. 4585-4591.Publisher: Royal Society of Chemistry Country of Publication: England NLM ID: 0372652 Publication Model: Print Cited Medium:

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  • 1-10 of  32 results for ""Amyloid Precursor Protein Secretases""