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Academic Journal

Efficient progranulin exit from the ER requires its interaction with prosaposin, a Surf4 cargo.

  • Authors : Devireddy S; Departments of Cell Biology and Neuroscience, Program in Cellular Neuroscience, Neurodegeneration and Repair, Wu Tsai Institute, Yale University School of Medicine, New Haven, CT.; Ferguson SM

Subjects: Endoplasmic Reticulum/Endoplasmic Reticulum/Endoplasmic Reticulum/*metabolism ; Membrane Proteins/Membrane Proteins/Membrane Proteins/*metabolism ; Progranulins/Progranulins/Progranulins/*metabolism

  • Source: The Journal of cell biology [J Cell Biol] 2022 Feb 07; Vol. 221 (2). Date of Electronic Publication: 2021 Dec 17.Publisher: Rockefeller University Press Country of Publication: United States NLM ID: 0375356 Publication Model:

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Academic Journal

Prosaposin facilitates sortilin-independent lysosomal trafficking of progranulin.

  • Authors : Zhou X; Department of Molecular Biology and Genetics, Cornell University, Ithaca, NY 14853 Weill Institute for Cell and Molecular Biology, Cornell University, Ithaca, NY 14853.; Sun L

Subjects: Adaptor Proteins, Vesicular Transport/Adaptor Proteins, Vesicular Transport/Adaptor Proteins, Vesicular Transport/*metabolism ; Intercellular Signaling Peptides and Proteins/Intercellular Signaling Peptides and Proteins/Intercellular Signaling Peptides and Proteins/*metabolism ; Lysosomes/Lysosomes/Lysosomes/*metabolism

  • Source: The Journal of cell biology [J Cell Biol] 2015 Sep 14; Vol. 210 (6), pp. 991-1002.Publisher: Rockefeller University Press Country of Publication: United States NLM ID: 0375356 Publication Model: Print Cited

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Academic Journal

The role of UDP-Glc:glycoprotein glucosyltransferase 1 in the maturation of an obligate substrate prosaposin.

  • Authors : Pearse BR; Department of Biochemistry and Molecular Biology, University of Massachusetts, Amherst, MA 01003, USA.; Tamura T

Subjects: Protein Folding*; Glucosyltransferases/Glucosyltransferases/Glucosyltransferases/*metabolism ; Protein Processing, Post-Translational/Protein Processing, Post-Translational/Protein Processing, Post-Translational/*physiology

  • Source: The Journal of cell biology [J Cell Biol] 2010 May 31; Vol. 189 (5), pp. 829-41. Date of Electronic Publication: 2010 May 24.Publisher: Rockefeller University Press Country of Publication: United States NLM ID: 0375356 Publication Model:

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Academic Journal

The Niemann-Pick type C2 protein loads isoglobotrihexosylceramide onto CD1d molecules and contributes to the thymic selection of NKT cells.

  • Authors : Schrantz N; Department of Immunology, The Scripps Research Institute, La Jolla, CA 92037, USA.; Sagiv Y

Subjects: Antigens, CD1/Antigens, CD1/Antigens, CD1/*metabolism ; Globosides/Globosides/Globosides/*metabolism ; T-Lymphocytes, Regulatory/T-Lymphocytes, Regulatory/T-Lymphocytes, Regulatory/*immunology

  • Source: The Journal of experimental medicine [J Exp Med] 2007 Apr 16; Vol. 204 (4), pp. 841-52. Date of Electronic Publication: 2007 Mar 26.Publisher: Rockefeller University Press Country of Publication: United States NLM ID: 2985109R Publication Model:

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