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Academic Journal

Complexin-2 redistributes to the membrane of muscle cells in response to insulin and contributes to GLUT4 translocation.

  • Authors : Pavarotti MA; Laboratorio de Fusión de Membranas y Exocitosis Acrosomal, Instituto de Histología y Embriología Mendoza Dr. Mario H Burgos, Mendoza, Argentina.; Consejo Nacional de Investigaciones Científicas y Técnicas, Buenos Aires, Argentina.

Subjects: Adaptor Proteins, Vesicular Transport/Adaptor Proteins, Vesicular Transport/Adaptor Proteins, Vesicular Transport/*metabolism ; Glucose Transporter Type 4/Glucose Transporter Type 4/Glucose Transporter Type 4/*metabolism ; Insulin/Insulin/Insulin/*pharmacology

  • Source: The Biochemical journal [Biochem J] 2021 Jan 29; Vol. 478 (2), pp. 407-422.Publisher: Published by Portland Press on behalf of the Biochemical Society Country of Publication: England NLM ID: 2984726R

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Academic Journal

Rac1-stimulated macropinocytosis enhances Gβγ activation of PI3Kβ.

  • Authors : Erami Z; Department of Molecular Pharmacology, Albert Einstein College of Medicine, Bronx, NY, U.S.A.; Khalil BD

Subjects: Class Ia Phosphatidylinositol 3-Kinase/Class Ia Phosphatidylinositol 3-Kinase/Class Ia Phosphatidylinositol 3-Kinase/*metabolism ; GTP-Binding Protein beta Subunits/GTP-Binding Protein beta Subunits/GTP-Binding Protein beta Subunits/*metabolism ; GTP-Binding Protein gamma Subunits/GTP-Binding Protein gamma Subunits/GTP-Binding Protein gamma Subunits/*metabolism

  • Source: The Biochemical journal [Biochem J] 2017 Nov 16; Vol. 474 (23), pp. 3903-3914. Date of Electronic Publication: 2017 Nov 16.Publisher: Published by Portland Press on behalf of the Biochemical Society Country of Publication: England NLM ID: 2984726R

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Academic Journal

Characterization of the activation of small GTPases by their GEFs on membranes using artificial membrane tethering.

  • Authors : Peurois F; Laboratoire de Biologie et Pharmacologie Appliquée, CNRS and Ecole Normale Supérieure Paris-Saclay, 61 Avenue du Président Wilson, Cachan 94235, France.; Veyron S

Subjects: ADP-Ribosylation Factor 1/ADP-Ribosylation Factor 1/ADP-Ribosylation Factor 1/*metabolism ; GTPase-Activating Proteins/GTPase-Activating Proteins/GTPase-Activating Proteins/*metabolism ; Guanine Nucleotide Exchange Factors/Guanine Nucleotide Exchange Factors/Guanine Nucleotide Exchange Factors/*metabolism

  • Source: The Biochemical journal [Biochem J] 2017 Mar 23; Vol. 474 (7), pp. 1259-1272. Date of Electronic Publication: 2017 Mar 23.Publisher: Published by Portland Press on behalf of the Biochemical Society Country of Publication: England NLM ID: 2984726R

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Academic Journal

Role for RalA downstream of Rac1 in skeletal muscle insulin signalling.

  • Authors : Takenaka N; Laboratory of Cell Biology, Department of Biological Science, Graduate School of Science, Osaka Prefecture University, 1-1 Gakuen-cho, Naka-ku, Sakai 599-8531, Japan.; Sumi Y

Subjects: Signal Transduction*; Insulin/Insulin/Insulin/*metabolism ; Muscle, Skeletal/Muscle, Skeletal/Muscle, Skeletal/*enzymology

  • Source: The Biochemical journal [Biochem J] 2015 Aug 01; Vol. 469 (3), pp. 445-54. Date of Electronic Publication: 2015 Jun 11.Publisher: Published by Portland Press on behalf of the Biochemical Society Country of Publication: England NLM ID: 2984726R

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Academic Journal

PIKfyve, MTMR3 and their product PtdIns5P regulate cancer cell migration and invasion through activation of Rac1.

Subjects: Carcinoma/Carcinoma/Carcinoma/*metabolism ; Neoplasm Proteins/Neoplasm Proteins/Neoplasm Proteins/*metabolism ; Phosphatidylinositol 3-Kinases/Phosphatidylinositol 3-Kinases/Phosphatidylinositol 3-Kinases/*metabolism

  • Source: The Biochemical journal [Biochem J] 2014 Aug 01; Vol. 461 (3), pp. 383-90.Publisher: Published by Portland Press on behalf of the Biochemical Society Country of Publication: England NLM ID: 2984726R

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Academic Journal

FilGAP and its close relatives: a mediator of Rho-Rac antagonism that regulates cell morphology and migration.

  • Authors : Nakamura F; Translational Medicine Division, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02115, USA.

Subjects: Actin Cytoskeleton/Actin Cytoskeleton/Actin Cytoskeleton/*metabolism ; Actins/Actins/Actins/*metabolism ; GTPase-Activating Proteins/GTPase-Activating Proteins/GTPase-Activating Proteins/*metabolism

  • Source: The Biochemical journal [Biochem J] 2013 Jul 01; Vol. 453 (1), pp. 17-25.Publisher: Published by Portland Press on behalf of the Biochemical Society Country of Publication: England NLM ID: 2984726R

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Academic Journal

A novel small-molecule screening strategy identifies mitoxantrone as a RhoGTPase inhibitor.

  • Authors : Bidaud-Meynard A; Université de Bordeaux, CNRS UMR 5248, CBMN, IECB, F-33607 Pessac Cedex, France.; Arma D

Subjects: Mitoxantrone/Mitoxantrone/Mitoxantrone/*pharmacology ; rac1 GTP-Binding Protein/rac1 GTP-Binding Protein/rac1 GTP-Binding Protein/*antagonists & inhibitors; Animals

  • Source: The Biochemical journal [Biochem J] 2013 Feb 15; Vol. 450 (1), pp. 55-62.Publisher: Published by Portland Press on behalf of the Biochemical Society Country of Publication: England NLM ID: 2984726R

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Academic Journal

SP-1 regulation of MMP-9 expression requires Ser586 in the PEST domain.

  • Authors : Murthy S; Department of Internal Medicine, University of Iowa Carver College of Medicine, Iowa City, IA 52242, USA.; Ryan AJ

Subjects: Gene Expression Regulation, Enzymologic*; Macrophages, Alveolar/Macrophages, Alveolar/Macrophages, Alveolar/*metabolism ; Matrix Metalloproteinase 9/Matrix Metalloproteinase 9/Matrix Metalloproteinase 9/*genetics

  • Source: The Biochemical journal [Biochem J] 2012 Jul 15; Vol. 445 (2), pp. 229-36.Publisher: Published by Portland Press on behalf of the Biochemical Society Country of Publication: England NLM ID: 2984726R

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Academic Journal

Force-induced apoptosis mediated by the Rac/Pak/p38 signalling pathway is regulated by filamin A.

  • Authors : Shifrin Y; Matrix Dynamics Group, Faculty of Dentistry, University of Toronto, Toronto, ON, Canada, M5S 3E2.; Pinto VI

Subjects: Apoptosis* ; Mechanotransduction, Cellular* ; Signal Transduction*

  • Source: The Biochemical journal [Biochem J] 2012 Jul 01; Vol. 445 (1), pp. 57-67.Publisher: Published by Portland Press on behalf of the Biochemical Society Country of Publication: England NLM ID: 2984726R

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Ligand-activated PPARδ inhibits UVB-induced senescence of human keratinocytes via PTEN-mediated inhibition of superoxide production.

  • Authors : Ham SA; Department of Animal Biotechnology, Konkuk University, Gwangjin-Gu, Seoul, Republic of Korea.; Hwang JS

Subjects: Keratinocytes/Keratinocytes/Keratinocytes/*radiation effects ; PTEN Phosphohydrolase/PTEN Phosphohydrolase/PTEN Phosphohydrolase/*physiology ; Superoxides/Superoxides/Superoxides/*antagonists & inhibitors

  • Source: The Biochemical journal [Biochem J] 2012 May 15; Vol. 444 (1), pp. 27-38.Publisher: Published by Portland Press on behalf of the Biochemical Society Country of Publication: England NLM ID: 2984726R

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  • 1-10 of  31 results for ""rac1 GTP-Binding Protein""