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Academic Journal

Rac1-stimulated macropinocytosis enhances Gβγ activation of PI3Kβ.

  • Authors : Erami Z; Department of Molecular Pharmacology, Albert Einstein College of Medicine, Bronx, NY, U.S.A.; Khalil BD

Subjects: Class Ia Phosphatidylinositol 3-Kinase/Class Ia Phosphatidylinositol 3-Kinase/Class Ia Phosphatidylinositol 3-Kinase/*metabolism ; GTP-Binding Protein beta Subunits/GTP-Binding Protein beta Subunits/GTP-Binding Protein beta Subunits/*metabolism ; GTP-Binding Protein gamma Subunits/GTP-Binding Protein gamma Subunits/GTP-Binding Protein gamma Subunits/*metabolism

  • Source: The Biochemical journal [Biochem J] 2017 Nov 16; Vol. 474 (23), pp. 3903-3914. Date of Electronic Publication: 2017 Nov 16.Publisher: Published by Portland Press on behalf of the Biochemical Society Country of Publication: England NLM ID: 2984726R

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Academic Journal

Role for RalA downstream of Rac1 in skeletal muscle insulin signalling.

  • Authors : Takenaka N; Laboratory of Cell Biology, Department of Biological Science, Graduate School of Science, Osaka Prefecture University, 1-1 Gakuen-cho, Naka-ku, Sakai 599-8531, Japan.; Sumi Y

Subjects: Signal Transduction*; Insulin/Insulin/Insulin/*metabolism ; Muscle, Skeletal/Muscle, Skeletal/Muscle, Skeletal/*enzymology

  • Source: The Biochemical journal [Biochem J] 2015 Aug 01; Vol. 469 (3), pp. 445-54. Date of Electronic Publication: 2015 Jun 11.Publisher: Published by Portland Press on behalf of the Biochemical Society Country of Publication: England NLM ID: 2984726R

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Academic Journal

PIKfyve, MTMR3 and their product PtdIns5P regulate cancer cell migration and invasion through activation of Rac1.

Subjects: Carcinoma/Carcinoma/Carcinoma/*metabolism ; Neoplasm Proteins/Neoplasm Proteins/Neoplasm Proteins/*metabolism ; Phosphatidylinositol 3-Kinases/Phosphatidylinositol 3-Kinases/Phosphatidylinositol 3-Kinases/*metabolism

  • Source: The Biochemical journal [Biochem J] 2014 Aug 01; Vol. 461 (3), pp. 383-90.Publisher: Published by Portland Press on behalf of the Biochemical Society Country of Publication: England NLM ID: 2984726R

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Academic Journal

A novel small-molecule screening strategy identifies mitoxantrone as a RhoGTPase inhibitor.

  • Authors : Bidaud-Meynard A; Université de Bordeaux, CNRS UMR 5248, CBMN, IECB, F-33607 Pessac Cedex, France.; Arma D

Subjects: Mitoxantrone/Mitoxantrone/Mitoxantrone/*pharmacology ; rac1 GTP-Binding Protein/rac1 GTP-Binding Protein/rac1 GTP-Binding Protein/*antagonists & inhibitors; Animals

  • Source: The Biochemical journal [Biochem J] 2013 Feb 15; Vol. 450 (1), pp. 55-62.Publisher: Published by Portland Press on behalf of the Biochemical Society Country of Publication: England NLM ID: 2984726R

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Academic Journal

EHD2 mediates trafficking from the plasma membrane by modulating Rac1 activity.

  • Authors : Benjamin S; Department of Cell Research and Immunology, Tel Aviv University, Ramat Aviv, Israel.; Weidberg H

Subjects: Carrier Proteins/Carrier Proteins/Carrier Proteins/*physiology ; Cell Membrane/Cell Membrane/Cell Membrane/*metabolism ; Protein Serine-Threonine Kinases/Protein Serine-Threonine Kinases/Protein Serine-Threonine Kinases/*metabolism

  • Source: The Biochemical journal [Biochem J] 2011 Nov 01; Vol. 439 (3), pp. 433-42.Publisher: Published by Portland Press on behalf of the Biochemical Society Country of Publication: England NLM ID: 2984726R

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Academic Journal

An activating mutant of Rac1 that fails to interact with Rho GDP-dissociation inhibitor stimulates membrane ruffling in mammalian cells.

  • Authors : Gandhi PN; Department of Pharmacology, Case Western Reserve University School of Medicine, 10900 Euclid Ave., Cleveland, OH 44106, USA.; Gibson RM

Subjects: Cell Membrane/Cell Membrane/Cell Membrane/*ultrastructure ; Guanine Nucleotide Dissociation Inhibitors/Guanine Nucleotide Dissociation Inhibitors/Guanine Nucleotide Dissociation Inhibitors/*metabolism ; rac1 GTP-Binding Protein/rac1 GTP-Binding Protein/rac1 GTP-Binding Protein/*metabolism

  • Source: The Biochemical journal [Biochem J] 2004 Mar 01; Vol. 378 (Pt 2), pp. 409-19.Publisher: Published by Portland Press on behalf of the Biochemical Society Country of Publication: England NLM ID: 2984726R

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Academic Journal

FilGAP and its close relatives: a mediator of Rho-Rac antagonism that regulates cell morphology and migration.

  • Authors : Nakamura F; Translational Medicine Division, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02115, USA.

Subjects: Actin Cytoskeleton/Actin Cytoskeleton/Actin Cytoskeleton/*metabolism ; Actins/Actins/Actins/*metabolism ; GTPase-Activating Proteins/GTPase-Activating Proteins/GTPase-Activating Proteins/*metabolism

  • Source: The Biochemical journal [Biochem J] 2013 Jul 01; Vol. 453 (1), pp. 17-25.Publisher: Published by Portland Press on behalf of the Biochemical Society Country of Publication: England NLM ID: 2984726R

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Academic Journal

Force-induced apoptosis mediated by the Rac/Pak/p38 signalling pathway is regulated by filamin A.

  • Authors : Shifrin Y; Matrix Dynamics Group, Faculty of Dentistry, University of Toronto, Toronto, ON, Canada, M5S 3E2.; Pinto VI

Subjects: Apoptosis* ; Mechanotransduction, Cellular* ; Signal Transduction*

  • Source: The Biochemical journal [Biochem J] 2012 Jul 01; Vol. 445 (1), pp. 57-67.Publisher: Published by Portland Press on behalf of the Biochemical Society Country of Publication: England NLM ID: 2984726R

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Academic Journal

Implication of the small GTPase Rac1 in the generation of reactive oxygen species in response to beta-amyloid in C6 astroglioma cells.

  • Authors : Lee M; Graduate School of Biotechnology, Korea University, 5-1 Anam-dong, Sungbuk-gu, Seoul, 136-701, Korea.; You HJ

Subjects: Amyloid beta-Peptides/Amyloid beta-Peptides/Amyloid beta-Peptides/*metabolism ; rac1 GTP-Binding Protein/rac1 GTP-Binding Protein/rac1 GTP-Binding Protein/*chemistry ; rac1 GTP-Binding Protein/rac1 GTP-Binding Protein/rac1 GTP-Binding Protein/*metabolism

  • Source: The Biochemical journal [Biochem J] 2002 Sep 15; Vol. 366 (Pt 3), pp. 937-43.Publisher: Published by Portland Press on behalf of the Biochemical Society Country of Publication: England NLM ID: 2984726R

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Academic Journal

Heregulin beta1 promotes breast cancer cell proliferation through Rac/ERK-dependent induction of cyclin D1 and p21Cip1.

  • Authors : Yang C; Department of Pharmacology and Institute for Translational Medicine and Therapeutics, University of Pennsylvania School of Medicine, Philadelphia, PA 19104, USA. ; Klein EA

Subjects: Cell Proliferation*; Breast Neoplasms/Breast Neoplasms/Breast Neoplasms/*pathology ; Cyclin D1/Cyclin D1/Cyclin D1/*biosynthesis

  • Source: The Biochemical journal [Biochem J] 2008 Feb 15; Vol. 410 (1), pp. 167-75.Publisher: Published by Portland Press on behalf of the Biochemical Society Country of Publication: England NLM ID: 2984726R

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  • 1-10 of  31 results for ""rac1 GTP-Binding Protein""