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Academic Journal

Use of phosphodiesterase inhibitors and prevalence of self-reported glaucoma in the United States.

  • Authors : Chen SP; Department of Ophthalmology, Stanford University School of Medicine, Stanford, California, United States of America.; Singh K

Subjects: Glaucoma/Glaucoma/Glaucoma/*chemically induced ; Phosphodiesterase Inhibitors/Phosphodiesterase Inhibitors/Phosphodiesterase Inhibitors/*adverse effects; Aged

  • Source: PloS one [PLoS One] 2017 Aug 17; Vol. 12 (8), pp. e0183388. Date of Electronic Publication: 2017 Aug 17 (Print Publication: 2017).Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: eCollection

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Academic Journal

2-Cl-C.OXT-A stimulates contraction through the suppression of phosphodiesterase activity in human induced pluripotent stem cell-derived cardiac organoids.

  • Authors : Kitsuka T; Department of Thoracic and Cardiovascular Surgery, Faculty of Medicine, Saga University, Saga, Japan.; Itoh M

Subjects: Adenosine/Adenosine/Adenosine/*pharmacology ; Induced Pluripotent Stem Cells/Induced Pluripotent Stem Cells/Induced Pluripotent Stem Cells/*cytology ; Myocardial Contraction/Myocardial Contraction/Myocardial Contraction/*drug effects

  • Source: PloS one [PLoS One] 2019 Jul 11; Vol. 14 (7), pp. e0213114. Date of Electronic Publication: 2019 Jul 11 (Print Publication: 2019).Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: eCollection

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Academic Journal

Rational discovery of dual-indication multi-target PDE/Kinase inhibitor for precision anti-cancer therapy using structural systems pharmacology.

  • Authors : Lim H; Ph.D. Program in Biochemistry, The Graduate Center, The City University of New York, New York, New York, United States of America.; He D

Subjects: Phosphodiesterase Inhibitors*; Antineoplastic Agents/Antineoplastic Agents/Antineoplastic Agents/*pharmacology ; Drug Discovery/Drug Discovery/Drug Discovery/*methods

  • Source: PLoS computational biology [PLoS Comput Biol] 2019 Jun 17; Vol. 15 (6), pp. e1006619. Date of Electronic Publication: 2019 Jun 17 (Print Publication: 2019).Publisher: Public Library of Science Country of Publication: United States NLM ID: 101238922 Publication Model: eCollection

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Academic Journal

The single cyclic nucleotide-specific phosphodiesterase of the intestinal parasite Giardia lamblia represents a potential drug target.

  • Authors : Kunz S; Institute of Parasitology, Vetsuisse Faculty, University of Bern, Bern, Switzerland.; Division of Medicinal Chemistry, Faculty of Sciences, Amsterdam Institute of Molecules, Medicines and Systems (AIMMS), Vrije Universiteit Amsterdam, Amsterdam, The Netherlands.

Subjects: Drug Discovery*; Antiprotozoal Agents/Antiprotozoal Agents/Antiprotozoal Agents/*pharmacology ; Giardia lamblia/Giardia lamblia/Giardia lamblia/*enzymology

  • Source: PLoS neglected tropical diseases [PLoS Negl Trop Dis] 2017 Sep 15; Vol. 11 (9), pp. e0005891. Date of Electronic Publication: 2017 Sep 15 (Print Publication: 2017).Publisher: Public Library of Science Country of Publication: United States NLM ID: 101291488 Publication Model: eCollection

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Academic Journal

Successful shortening of tuberculosis treatment using adjuvant host-directed therapy with FDA-approved phosphodiesterase inhibitors in the mouse model.

  • Authors : Maiga M; Center for Tuberculosis Research, School of Medicine, Johns Hopkins University, Baltimore, Maryland, United States of America.; Agarwal N

Subjects: Antitubercular Agents/Antitubercular Agents/Antitubercular Agents/*therapeutic use ; Phosphodiesterase Inhibitors/Phosphodiesterase Inhibitors/Phosphodiesterase Inhibitors/*therapeutic use ; Tuberculosis/Tuberculosis/Tuberculosis/*therapy

  • Source: PloS one [PLoS One] 2012; Vol. 7 (2), pp. e30749. Date of Electronic Publication: 2012 Feb 03.Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: Print-Electronic

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Academic Journal

Sildenafil-evoked photoreceptor oxidative stress in vivo is unrelated to impaired visual performance in mice.

  • Authors : Berkowitz BA; Department of Ophthalmology, Visual and Anatomical Sciences, Wayne State University School of Medicine, Detroit, Michigan, United States of America.; Podolsky RH

Subjects: Oxidative Stress* ; Vision, Ocular*; Phosphodiesterase Inhibitors/Phosphodiesterase Inhibitors/Phosphodiesterase Inhibitors/*pharmacology

  • Source: PloS one [PLoS One] 2021 Mar 04; Vol. 16 (3), pp. e0245161. Date of Electronic Publication: 2021 Mar 04 (Print Publication: 2021).Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: eCollection

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Academic Journal

Pentoxifylline for Anemia in Chronic Kidney Disease: A Systematic Review and Meta-Analysis.

Subjects: Anemia/Anemia/Anemia/*complications ; Anemia/Anemia/Anemia/*drug therapy ; Pentoxifylline/Pentoxifylline/Pentoxifylline/*therapeutic use

  • Source: PloS one [PLoS One] 2015 Aug 03; Vol. 10 (8), pp. e0134104. Date of Electronic Publication: 2015 Aug 03 (Print Publication: 2015).Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: eCollection

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Academic Journal

Characterization of binding and inhibitory properties of TAK-063, a novel phosphodiesterase 10A inhibitor.

  • Authors : Harada A; Central Nervous System Drug Discovery Unit, Pharmaceutical Research Division, Takeda Pharmaceutical Company Limited, Fujisawa, Japan.; Suzuki K

Subjects: Brain/Brain/Brain/*drug effects ; Phosphodiesterase Inhibitors/Phosphodiesterase Inhibitors/Phosphodiesterase Inhibitors/*pharmacology ; Phosphoric Diester Hydrolases/Phosphoric Diester Hydrolases/Phosphoric Diester Hydrolases/*metabolism

  • Source: PloS one [PLoS One] 2015 Mar 27; Vol. 10 (3), pp. e0122197. Date of Electronic Publication: 2015 Mar 27 (Print Publication: 2015).Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: eCollection

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Academic Journal

Phosphodiesterase 3/4 inhibitor zardaverine exhibits potent and selective antitumor activity against hepatocellular carcinoma both in vitro and in vivo independently of phosphodiesterase inhibition.

  • Authors : Sun L; Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, China.; Quan H

Subjects: Antineoplastic Agents/Antineoplastic Agents/Antineoplastic Agents/*therapeutic use ; Carcinoma, Hepatocellular/Carcinoma, Hepatocellular/Carcinoma, Hepatocellular/*drug therapy ; Liver Neoplasms/Liver Neoplasms/Liver Neoplasms/*drug therapy

  • Source: PloS one [PLoS One] 2014 Mar 05; Vol. 9 (3), pp. e90627. Date of Electronic Publication: 2014 Mar 05 (Print Publication: 2014).Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: eCollection

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Academic Journal

Anti-inflammatory and cardioprotective effects of tadalafil in diabetic mice.

  • Authors : Varma A; Division of Cardiology, Department of Internal Medicine, VCU Pauley Heart Center, Virginia Commonwealth University, Richmond, Virginia, USA.; Das A

Subjects: Carbolines/Carbolines/Carbolines/*pharmacology ; Diabetes Mellitus, Experimental/Diabetes Mellitus, Experimental/Diabetes Mellitus, Experimental/*drug therapy ; Myocardial Infarction/Myocardial Infarction/Myocardial Infarction/*drug therapy

  • Source: PloS one [PLoS One] 2012; Vol. 7 (9), pp. e45243. Date of Electronic Publication: 2012 Sep 21.Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: Print-Electronic

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  • 1-10 of  870 results for ""PHOSPHODIESTERASE inhibitors""