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  • 1-10 of  1,976 results for ""High-Throughput Screening Assays""
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Academic Journal

Hit screening with multivariate robust outlier detection.

  • Authors : Leong HS; Data Sciences and Quantitative Biology, Discovery Sciences, Biopharmaceuticals R&D, AstraZeneca, Cambridge, United Kingdom.; Zhang T

Subjects: High-Throughput Screening Assays*/High-Throughput Screening Assays*/High-Throughput Screening Assays*/methods; Multivariate Analysis ; Humans

  • Source: PloS one [PLoS One] 2024 Sep 12; Vol. 19 (9), pp. e0310433. Date of Electronic Publication: 2024 Sep 12 (Print Publication: 2024).Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: eCollection

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Academic Journal

A high-throughput behavioral screening platform for measuring chemotaxis by C. elegans.

  • Authors : Fryer E; Department of Molecular and Cellular Physiology, Stanford University, Stanford, California, United States of America.; Department of Plant Biology, Carnegie Institution for Science, Stanford, California, United States of America.

Subjects: Caenorhabditis elegans*/Caenorhabditis elegans*/Caenorhabditis elegans*/physiology ; Caenorhabditis elegans*/Caenorhabditis elegans*/Caenorhabditis elegans*/drug effects ; Chemotaxis*

  • Source: PLoS biology [PLoS Biol] 2024 Jun 27; Vol. 22 (6), pp. e3002672. Date of Electronic Publication: 2024 Jun 27 (Print Publication: 2024).Publisher: Public Library of Science Country of Publication: United States NLM ID: 101183755 Publication Model: eCollection

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Academic Journal

A homogeneous time-resolved fluorescence screen to identify SIRT2 deacetylase and defatty-acylase inhibitors.

  • Authors : Yang J; Department of Molecular Biology, Rowan-Virtua School of Translational Biomedical Engineering & Sciences, Rowan University, Stratford, New Jersey, United States of America.; Department of Molecular Biology, Rowan-Virtua School of Osteopathic Medicine, Rowan University, Stratford, New Jersey, United States of America.

Subjects: Sirtuin 2*/Sirtuin 2*/Sirtuin 2*/antagonists & inhibitors ; Sirtuin 2*/Sirtuin 2*/Sirtuin 2*/metabolism ; High-Throughput Screening Assays*/High-Throughput Screening Assays*/High-Throughput Screening Assays*/methods

  • Source: PloS one [PLoS One] 2024 Jun 24; Vol. 19 (6), pp. e0305000. Date of Electronic Publication: 2024 Jun 24 (Print Publication: 2024).Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: eCollection

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Academic Journal

Phenotypic high-throughput screening identifies aryl hydrocarbon receptor agonism as common inhibitor of toxin-induced retinal pigment epithelium cell death.

  • Authors : Schustak J; Department of Ophthalmology, BioMedical Research, Novartis, Cambridge, Massachusetts, United States of America.; Han H

Subjects: Retinal Pigment Epithelium*/Retinal Pigment Epithelium*/Retinal Pigment Epithelium*/metabolism ; High-Throughput Screening Assays*; Humans

  • Source: PloS one [PLoS One] 2024 Apr 18; Vol. 19 (4), pp. e0301239. Date of Electronic Publication: 2024 Apr 18 (Print Publication: 2024).Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: eCollection

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Academic Journal

Bayesian inference of relative fitness on high-throughput pooled competition assays.

  • Authors : Razo-Mejia M; Department of Biology, Stanford University, Stanford, California, United States of America.; Mani M

Subjects: Software* ; High-Throughput Screening Assays*; Bayes Theorem

  • Source: PLoS computational biology [PLoS Comput Biol] 2024 Mar 15; Vol. 20 (3), pp. e1011937. Date of Electronic Publication: 2024 Mar 15 (Print Publication: 2024).Publisher: Public Library of Science Country of Publication: United States NLM ID: 101238922 Publication Model: eCollection

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Academic Journal

High-throughput screening identifies cell cycle-associated signaling cascades that regulate a multienzyme glucosome assembly in human cells.

  • Authors : Schmitt DL; Department of Chemistry and Biochemistry, University of Maryland Baltimore County (UMBC), Baltimore, Maryland, United States of America.; Dranchak P

Subjects: Aurora Kinase A* ; High-Throughput Screening Assays*; Humans

  • Source: PloS one [PLoS One] 2023 Aug 04; Vol. 18 (8), pp. e0289707. Date of Electronic Publication: 2023 Aug 04 (Print Publication: 2023).Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: eCollection

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Academic Journal

In-vitro high-throughput library screening-Kinetics and molecular docking studies of potent inhibitors of α-glucosidase.

  • Authors : Ali M; Department of Chemistry, COMSATS University Islamabad, KPK, Abbottabad, Pakistan.; Department of Chemistry, Higher Education Department, Government Postgraduate College No.1, Abbottabad, KP, Pakistan.

Subjects: alpha-Glucosidases* ; High-Throughput Screening Assays*; Kinetics

  • Source: PloS one [PLoS One] 2023 Jun 30; Vol. 18 (6), pp. e0286159. Date of Electronic Publication: 2023 Jun 30 (Print Publication: 2023).Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: eCollection

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Academic Journal

A high-throughput method to deliver targeted optogenetic stimulation to moving C. elegans populations.

  • Authors : Liu M; Department of Physics, Princeton University, Princeton, New Jersey, United States of America.; Kumar S

Subjects: High-Throughput Screening Assays*; Caenorhabditis elegans/Caenorhabditis elegans/Caenorhabditis elegans/*physiology ; Mechanotransduction, Cellular/Mechanotransduction, Cellular/Mechanotransduction, Cellular/*physiology

  • Source: PLoS biology [PLoS Biol] 2022 Jan 28; Vol. 20 (1), pp. e3001524. Date of Electronic Publication: 2022 Jan 28 (Print Publication: 2022).Publisher: Public Library of Science Country of Publication: United States NLM ID: 101183755 Publication Model: eCollection

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Academic Journal

Quantitative high-throughput screening assays for the discovery and development of SIRPα-CD47 interaction inhibitors.

  • Authors : Miller TW; Paradigm Shift Therapeutics LLC, Rockville, Maryland, United States of America.; Laboratory of Pathology, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, Maryland, United States of America.

Subjects: Antibodies, Monoclonal, Humanized/Antibodies, Monoclonal, Humanized/Antibodies, Monoclonal, Humanized/*pharmacology ; Antigens, Differentiation/Antigens, Differentiation/Antigens, Differentiation/*metabolism ; CD47 Antigen/CD47 Antigen/CD47 Antigen/*metabolism

  • Source: PloS one [PLoS One] 2019 Jul 05; Vol. 14 (7), pp. e0218897. Date of Electronic Publication: 2019 Jul 05 (Print Publication: 2019).Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: eCollection

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Academic Journal

Leveraging high-throughput screening data, deep neural networks, and conditional generative adversarial networks to advance predictive toxicology.

  • Authors : Green AJ; Department of Biological Sciences, and the Bioinformatics Research Center, NC State University, Raleigh, North Carolina, United States of America.; Mohlenkamp MJ

Subjects: Computational Biology* ; High-Throughput Screening Assays* ; Neural Networks, Computer*

  • Source: PLoS computational biology [PLoS Comput Biol] 2021 Jul 02; Vol. 17 (7), pp. e1009135. Date of Electronic Publication: 2021 Jul 02 (Print Publication: 2021).Publisher: Public Library of Science Country of Publication: United States NLM ID: 101238922 Publication Model: eCollection

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  • 1-10 of  1,976 results for ""High-Throughput Screening Assays""