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Academic Journal

pH-responsive targeted nanoparticles release ERK-inhibitor in the hypoxic zone and sensitize free gemcitabine in mutant K-Ras-addicted pancreatic cancer cells and mouse model.

  • Authors : Dutta D; Department of Coatings and Polymeric Materials, North Dakota State University, Fargo, ND, United States of America.; Ray P

Subjects: Deoxycytidine*/Deoxycytidine*/Deoxycytidine*/analogs & derivatives ; Deoxycytidine*/Deoxycytidine*/Deoxycytidine*/pharmacology ; Deoxycytidine*/Deoxycytidine*/Deoxycytidine*/administration & dosage

  • Source: PloS one [PLoS One] 2024 Apr 30; Vol. 19 (4), pp. e0297749. Date of Electronic Publication: 2024 Apr 30 (Print Publication: 2024).Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: eCollection

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Academic Journal

Ataxia telangiectasia and Rad3-related inhibition by AZD6738 enhances gemcitabine-induced cytotoxic effects in bladder cancer cells.

  • Authors : Isono M; Department of Urology, National Defense Medical College, Tokorozawa, Japan.; Okubo K

Subjects: Antineoplastic Agents*/Antineoplastic Agents*/Antineoplastic Agents*/pharmacology ; Antineoplastic Combined Chemotherapy Protocols*/Antineoplastic Combined Chemotherapy Protocols*/Antineoplastic Combined Chemotherapy Protocols*/pharmacology ; Ataxia Telangiectasia Mutated Proteins*/Ataxia Telangiectasia Mutated Proteins*/Ataxia Telangiectasia Mutated Proteins*/metabolism

  • Source: PloS one [PLoS One] 2022 Apr 12; Vol. 17 (4), pp. e0266476. Date of Electronic Publication: 2022 Apr 12 (Print Publication: 2022).Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: eCollection

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Academic Journal

Risk factors for severe neutropenia in pancreatic cancer patients treated with gemcitabine/nab-paclitaxel combination therapy.

  • Authors : Ito G; Division of Drug Informatics, Keio University Faculty of Pharmacy, Tokyo, Japan.; Kawakami K

Subjects: Pancreatic Neoplasms*/Pancreatic Neoplasms*/Pancreatic Neoplasms*/drug therapy ; Gemcitabine* ; Deoxycytidine*/Deoxycytidine*/Deoxycytidine*/analogs & derivatives

  • Source: PloS one [PLoS One] 2021 Jul 14; Vol. 16 (7), pp. e0254726. Date of Electronic Publication: 2021 Jul 14 (Print Publication: 2021).Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: eCollection

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Academic Journal

Gemcitabine-induced Gli-dependent activation of hedgehog pathway resists to the treatment of urothelial carcinoma cells.

  • Authors : Chang YH; Department of Medical Laboratory Science and Biotechnology, College of Medicine, National Cheng Kung University, Tainan, Taiwan.; Tam HL

Subjects: Signal Transduction*/Signal Transduction*/Signal Transduction*/drug effects; Deoxycytidine/Deoxycytidine/Deoxycytidine/*analogs & derivatives ; Hedgehog Proteins/Hedgehog Proteins/Hedgehog Proteins/*metabolism

  • Source: PloS one [PLoS One] 2021 Jul 08; Vol. 16 (7), pp. e0254011. Date of Electronic Publication: 2021 Jul 08 (Print Publication: 2021).Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: eCollection

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Academic Journal

Cytoplasmic RRM1 activation as an acute response to gemcitabine treatment is involved in drug resistance of pancreatic cancer cells.

  • Authors : Kato T; Department of Hepatobiliary and Pancreatic Surgery, Graduate School of Medicine, Tokyo Medical and Dental University, Tokyo, Japan.; Ono H

Subjects: Drug Resistance, Neoplasm*/Drug Resistance, Neoplasm*/Drug Resistance, Neoplasm*/drug effects ; Up-Regulation*/Up-Regulation*/Up-Regulation*/drug effects; Cytoplasm/Cytoplasm/Cytoplasm/*metabolism

  • Source: PloS one [PLoS One] 2021 Jun 10; Vol. 16 (6), pp. e0252917. Date of Electronic Publication: 2021 Jun 10 (Print Publication: 2021).Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: eCollection

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Academic Journal

Phase II trial of cisplatin, gemcitabine and pembrolizumab for platinum-resistant ovarian cancer.

  • Authors : Walsh CS; Department of Obstetrics and Gynecology, Division of Gynecologic Oncology, Cedars-Sinai Medical Center, Los Angeles, California, United States of America.; Cedars-Sinai Cancer, Cedars-Sinai Medical Center, Los Angeles, California, United States of America.

Subjects: Antibodies, Monoclonal, Humanized/Antibodies, Monoclonal, Humanized/Antibodies, Monoclonal, Humanized/*administration & dosage ; Antineoplastic Combined Chemotherapy Protocols/Antineoplastic Combined Chemotherapy Protocols/Antineoplastic Combined Chemotherapy Protocols/*therapeutic use ; Cisplatin/Cisplatin/Cisplatin/*administration & dosage

  • Source: PloS one [PLoS One] 2021 Jun 03; Vol. 16 (6), pp. e0252665. Date of Electronic Publication: 2021 Jun 03 (Print Publication: 2021).Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: eCollection

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Academic Journal

Quantification of fluorophore distribution and therapeutic response in matched in vivo and ex vivo pancreatic cancer model systems.

  • Authors : Solanki A; Department of Biomedical Engineering, Oregon Health & Science University, Portland, Oregon, United States of America.; King D

Subjects: Disease Models, Animal*; Carcinoma, Pancreatic Ductal/Carcinoma, Pancreatic Ductal/Carcinoma, Pancreatic Ductal/*pathology ; Deoxycytidine/Deoxycytidine/Deoxycytidine/*analogs & derivatives

  • Source: PloS one [PLoS One] 2020 Feb 25; Vol. 15 (2), pp. e0229407. Date of Electronic Publication: 2020 Feb 25 (Print Publication: 2020).Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: eCollection

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Academic Journal

Quercetin potentializes the respective cytotoxic activity of gemcitabine or doxorubicin on 3D culture of AsPC-1 or HepG2 cells, through the inhibition of HIF-1α and MDR1.

  • Authors : Hassan S; Regenerative Nanomedicine, INSERM UMR 1260, FMTS, University of Strasbourg, Strasbourg, France.; Platform eBiocyt-UPS1401, Faculty of Pharmacy, University of Strasbourg, Strasbourg, France.

Subjects: Antineoplastic Agents/Antineoplastic Agents/Antineoplastic Agents/*pharmacology ; Antineoplastic Combined Chemotherapy Protocols/Antineoplastic Combined Chemotherapy Protocols/Antineoplastic Combined Chemotherapy Protocols/*pharmacology ; Antioxidants/Antioxidants/Antioxidants/*pharmacology

  • Source: PloS one [PLoS One] 2020 Oct 14; Vol. 15 (10), pp. e0240676. Date of Electronic Publication: 2020 Oct 14 (Print Publication: 2020).Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: eCollection

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Academic Journal

Comparing the intra-tumoral distribution of Gemcitabine, 5-Fluorouracil, and Capecitabine in a murine model of pancreatic ductal adenocarcinoma.

  • Authors : Fanchon LM; Department of Medical Physics, Memorial Sloan Kettering Cancer Center, New York, NY, United States of America.; Russell J

Subjects: Antimetabolites, Antineoplastic/Antimetabolites, Antineoplastic/Antimetabolites, Antineoplastic/*pharmacokinetics ; Capecitabine/Capecitabine/Capecitabine/*pharmacokinetics ; Carcinoma, Pancreatic Ductal/Carcinoma, Pancreatic Ductal/Carcinoma, Pancreatic Ductal/*metabolism

  • Source: PloS one [PLoS One] 2020 Apr 16; Vol. 15 (4), pp. e0231745. Date of Electronic Publication: 2020 Apr 16 (Print Publication: 2020).Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: eCollection

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Academic Journal

Key necroptotic proteins are required for Smac mimetic-mediated sensitization of cholangiocarcinoma cells to TNF-α and chemotherapeutic gemcitabine-induced necroptosis.

  • Authors : Akara-Amornthum P; Graduate Program in Clinical Biochemistry and Molecular Medicine, Department of Clinical Chemistry, Faculty of Allied Health Sciences, Chulalongkorn University, Bangkok, Thailand.; Lomphithak T

Subjects: Bridged Bicyclo Compounds, Heterocyclic/Bridged Bicyclo Compounds, Heterocyclic/Bridged Bicyclo Compounds, Heterocyclic/*pharmacology ; Deoxycytidine/Deoxycytidine/Deoxycytidine/*analogs & derivatives ; Necroptosis/Necroptosis/Necroptosis/*drug effects

  • Source: PloS one [PLoS One] 2020 Jan 08; Vol. 15 (1), pp. e0227454. Date of Electronic Publication: 2020 Jan 08 (Print Publication: 2020).Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: eCollection

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  • 1-10 of  2,458 results for ""Deoxycytidine""