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Academic Journal

Beyond hemostasis: a snake venom serine protease with potassium channel blocking and potential antitumor activities.

  • Authors : Boldrini-França J; School of Pharmaceutical Sciences of Ribeirão Preto, University of São Paulo, Av. do Café s/n°, 14040-903, Ribeirão Preto, SP, Brazil.; University of Vila Velha, Av. Comissário José Dantas de Melo, 21, Boa Vista II, 29102-920, Vila Velha, ES, Brazil.

Subjects: Hemostasis*; Potassium Channel Blockers/Potassium Channel Blockers/Potassium Channel Blockers/*pharmacology ; Potassium Channels/Potassium Channels/Potassium Channels/*metabolism

  • Source: Scientific reports [Sci Rep] 2020 Mar 11; Vol. 10 (1), pp. 4476. Date of Electronic Publication: 2020 Mar 11.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited

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Academic Journal

Altered plasma levels of the SARS-CoV-2-related proteins ACE2 and TMPRSS2 in patients with Crohn's disease.

  • Authors : Sáez-Leyva J; Instituto de Neurociencias de Alicante, Universidad Miguel Hernández-CSIC, San Juan de Alicante, Spain.; Centro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas (CIBERNED), Madrid, Spain.

Subjects: Angiotensin-Converting Enzyme 2*/Angiotensin-Converting Enzyme 2*/Angiotensin-Converting Enzyme 2*/metabolism ; Angiotensin-Converting Enzyme 2*/Angiotensin-Converting Enzyme 2*/Angiotensin-Converting Enzyme 2*/blood ; Crohn Disease*/Crohn Disease*/Crohn Disease*/blood

  • Source: Scientific reports [Sci Rep] 2024 Dec 05; Vol. 14 (1), pp. 30346. Date of Electronic Publication: 2024 Dec 05.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited

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Academic Journal

Rhomboid-like 2 correlated with TME infiltration inhibits cuproptosis-related genes and drives malignant phenotype in clear cell renal cell carcinoma.

  • Authors : Che Z; Department of Urology, The First Affiliated Hospital of Hainan Medical University, No. 31 Longhua Road, Longhua District, Haikou, 570102, Hainan Province, China.; Jin W

Subjects: Carcinoma, Renal Cell*/Carcinoma, Renal Cell*/Carcinoma, Renal Cell*/genetics ; Carcinoma, Renal Cell*/Carcinoma, Renal Cell*/Carcinoma, Renal Cell*/pathology ; Carcinoma, Renal Cell*/Carcinoma, Renal Cell*/Carcinoma, Renal Cell*/metabolism

  • Source: Scientific reports [Sci Rep] 2024 Nov 07; Vol. 14 (1), pp. 27053. Date of Electronic Publication: 2024 Nov 07.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited

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Academic Journal

Effect of carbon black and silicon dioxide nanoparticle exposure on corona receptor ACE2 and TMPRSS2 expression in the ocular surface.

  • Authors : Li X; Department of Ophthalmology, Guro Hospital, Korea University College of Medicine, 80, Guro-dong, Guro-gu, Seoul, 152-703, South Korea.; Li X

Subjects: Angiotensin-Converting Enzyme 2*/Angiotensin-Converting Enzyme 2*/Angiotensin-Converting Enzyme 2*/metabolism ; Angiotensin-Converting Enzyme 2*/Angiotensin-Converting Enzyme 2*/Angiotensin-Converting Enzyme 2*/genetics ; Silicon Dioxide*/Silicon Dioxide*/Silicon Dioxide*/toxicity

  • Source: Scientific reports [Sci Rep] 2024 Nov 06; Vol. 14 (1), pp. 27023. Date of Electronic Publication: 2024 Nov 06.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited

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Academic Journal

Improved efficacy of SARS-CoV-2 isolation from COVID-19 clinical specimens using VeroE6 cells overexpressing TMPRSS2 and human ACE2.

  • Authors : Kinoshita H; Department of Virology I, National Institute of Infectious Diseases, Tokyo, Japan.; Yamamoto T

Subjects: Angiotensin-Converting Enzyme 2*/Angiotensin-Converting Enzyme 2*/Angiotensin-Converting Enzyme 2*/metabolism ; Angiotensin-Converting Enzyme 2*/Angiotensin-Converting Enzyme 2*/Angiotensin-Converting Enzyme 2*/genetics ; Serine Endopeptidases*/Serine Endopeptidases*/Serine Endopeptidases*/metabolism

  • Source: Scientific reports [Sci Rep] 2024 Oct 22; Vol. 14 (1), pp. 24858. Date of Electronic Publication: 2024 Oct 22.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited

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Academic Journal

PK/PD investigation of antiviral host matriptase/TMPRSS2 inhibitors in cell models.

  • Authors : Gamba D; Department of Pharmacology and Toxicology, University of Veterinary Medicine, István Utca 2, 1078, Budapest, Hungary.; van Eijk N

Subjects: Antiviral Agents*/Antiviral Agents*/Antiviral Agents*/pharmacology ; Hepatocytes*/Hepatocytes*/Hepatocytes*/virology ; Hepatocytes*/Hepatocytes*/Hepatocytes*/metabolism

  • Source: Scientific reports [Sci Rep] 2024 Jul 18; Vol. 14 (1), pp. 16621. Date of Electronic Publication: 2024 Jul 18.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited

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Academic Journal

Computational screening combined with well-tempered metadynamics simulations identifies potential TMPRSS2 inhibitors.

  • Authors : Sharanya CS; Transdisciplinary Biology, Rajiv Gandhi Centre for Biotechnology, Thiruvananthapuram, Kerala, India.; Wilbee DS

Subjects: Serine Endopeptidases*/Serine Endopeptidases*/Serine Endopeptidases*/metabolism ; Serine Endopeptidases*/Serine Endopeptidases*/Serine Endopeptidases*/chemistry ; Molecular Dynamics Simulation*

  • Source: Scientific reports [Sci Rep] 2024 Jul 13; Vol. 14 (1), pp. 16197. Date of Electronic Publication: 2024 Jul 13.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited

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Academic Journal

Bacillaceae serine proteases and Streptomyces epsilon-poly-L-lysine synergistically inactivate Caliciviridae by inhibiting RNA genome release.

  • Authors : Yamamoto S; Department of Microbiology, Sapporo Medical University School of Medicine, Sapporo, 060-8556, Japan.; Ogasawara N

Subjects: Streptomyces*/Streptomyces*/Streptomyces*/enzymology ; Polylysine*/Polylysine*/Polylysine*/pharmacology ; Polylysine*/Polylysine*/Polylysine*/chemistry

  • Source: Scientific reports [Sci Rep] 2024 Jul 02; Vol. 14 (1), pp. 15181. Date of Electronic Publication: 2024 Jul 02.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited

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Editorial & Opinion

Structural basis for the recognition of HCoV-HKU1 by human TMPRSS2.

  • Authors : Xia L; Center for Infectious Disease Research, Research Center for Industries of the Future, Zhejiang Key Laboratory of Structural Biology, School of Life Sciences, Westlake University. Institute of Biology, Westlake Institute for Advanced Study, Hangzhou, Zhejiang, China.; Westlake Laboratory of Life Sciences and Biomedicine, Hangzhou, Zhejiang, China.

Subjects: Serine Endopeptidases*/Serine Endopeptidases*/Serine Endopeptidases*/metabolism ; Serine Endopeptidases*/Serine Endopeptidases*/Serine Endopeptidases*/chemistry; Humans

  • Source: Cell research [Cell Res] 2024 Jul; Vol. 34 (7), pp. 526-529. Date of Electronic Publication: 2024 Apr 19.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 9425763 Publication Model: Print-Electronic Cited

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Academic Journal

Generation of a lethal mouse model expressing human ACE2 and TMPRSS2 for SARS-CoV-2 infection and pathogenesis.

  • Authors : Jeong GU; Center for Infectious Disease Vaccine and Diagnosis Innovation (CEVI), Korea Research Institute of Chemical Technology, Daejeon, Republic of Korea.; Division of Infectious Diseases, Department of Pediatrics, Boston Children's Hospital, Boston, MA, USA.

Subjects: Angiotensin-Converting Enzyme 2*/Angiotensin-Converting Enzyme 2*/Angiotensin-Converting Enzyme 2*/genetics ; Angiotensin-Converting Enzyme 2*/Angiotensin-Converting Enzyme 2*/Angiotensin-Converting Enzyme 2*/metabolism ; COVID-19*/COVID-19*/COVID-19*/virology SARS-CoV-2 variants

  • Source: Experimental & molecular medicine [Exp Mol Med] 2024 May; Vol. 56 (5), pp. 1221-1229. Date of Electronic Publication: 2024 May 31.Publisher: Nature Publishing Group Country of Publication: United States NLM ID: 9607880 Publication Model: Print-Electronic

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  • 1-10 of  454 results for ""SERINE proteinases""