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Academic Journal

Evidence of membranolytic targeting and intracellular citrullination in neutrophils isolated from patients with rheumatoid arthritis.

  • Authors : Moadab F; Division of Rheumatology, Department of Medicine, University of Washington, 750 Republican Street, Room E507, Seattle, WA, 99108, USA.; Wang X

Subjects: Neutrophils*/Neutrophils*/Neutrophils*/metabolism ; Neutrophils*/Neutrophils*/Neutrophils*/immunology ; Arthritis, Rheumatoid*/Arthritis, Rheumatoid*/Arthritis, Rheumatoid*/metabolism

  • Source: Scientific reports [Sci Rep] 2024 Jul 05; Vol. 14 (1), pp. 15511. Date of Electronic Publication: 2024 Jul 05.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited

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Academic Journal

Caspase-7 activates ASM to repair gasdermin and perforin pores.

  • Authors : Nozaki K; Department of Immunology, Duke University School of Medicine, Durham, NC, USA.; Department of Molecular Genetics and Microbiology, Duke University School of Medicine, Durham, NC, USA.

Subjects: Caspase 7*/Caspase 7*/Caspase 7*/metabolism ; Perforin*/Perforin*/Perforin*/metabolism ; Phosphate-Binding Proteins*/Phosphate-Binding Proteins*/Phosphate-Binding Proteins*/metabolism Chromobacterium violaceum

  • Source: Nature [Nature] 2022 Jun; Vol. 606 (7916), pp. 960-967. Date of Electronic Publication: 2022 Jun 15.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 0410462 Publication Model: Print-Electronic Cited

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Academic Journal

Gene therapy of prostate cancer using liposomes containing perforin expression vector driven by the promoter of prostate-specific antigen gene.

  • Authors : Mizutani K; Department of Urology, Gifu University Graduate School of Medicine, 1-1 Yanagido, Gifu, Gifu, 501-1194, Japan. .; Department of Urology, Kizawa Memorial Hospital, Minokamo, Gifu, 505-8503, Japan. .

Subjects: Genetic Therapy/Genetic Therapy/Genetic Therapy/*methods ; Immunologic Surveillance/Immunologic Surveillance/Immunologic Surveillance/*genetics ; Kallikreins/Kallikreins/Kallikreins/*genetics

  • Source: Scientific reports [Sci Rep] 2022 Jan 27; Vol. 12 (1), pp. 1442. Date of Electronic Publication: 2022 Jan 27.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited

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Academic Journal

Perforin proteostasis is regulated through its C2 domain: supra-physiological cell death mediated by T431D-perforin.

  • Authors : Brennan AJ; Killer Cell Biology Laboratory, Peter MacCallum Cancer Centre, Melbourne, VIC, Australia. .; Law RHP

Subjects: Apoptosis*; Perforin/Perforin/Perforin/*metabolism; Animals

  • Source: Cell death and differentiation [Cell Death Differ] 2018 Aug; Vol. 25 (8), pp. 1517-1529. Date of Electronic Publication: 2018 Feb 07.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 9437445 Publication Model: Print-Electronic Cited

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Academic Journal

Cytolytic DNA vaccine encoding lytic perforin augments the maturation of- and antigen presentation by- dendritic cells in a time-dependent manner.

  • Authors : Wijesundara DK; Virology Laboratory, The Basil Hetzel Institute for Translational Health Research, The University of Adelaide, Adelaide, South Australia, Australia. .; Yu W

Subjects: Antigen Presentation*; Antigens/Antigens/Antigens/*immunology ; Dendritic Cells/Dendritic Cells/Dendritic Cells/*immunology

  • Source: Scientific reports [Sci Rep] 2017 Aug 17; Vol. 7 (1), pp. 8530. Date of Electronic Publication: 2017 Aug 17.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited

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Academic Journal

Increased Uterine NK cell numbers and perforin expression during the implantation phase in IVF Cycles with GnRH Antagonist Protocol.

  • Authors : Xu B; Reproductive Medical Center of Ruijin Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai 200025, China.; Wang J

Subjects: Embryo, Mammalian/Embryo, Mammalian/Embryo, Mammalian/*drug effects ; Follicle Stimulating Hormone/Follicle Stimulating Hormone/Follicle Stimulating Hormone/*pharmacology ; Gonadotropin-Releasing Hormone/Gonadotropin-Releasing Hormone/Gonadotropin-Releasing Hormone/*antagonists & inhibitors

  • Source: Scientific reports [Sci Rep] 2017 Jan 03; Vol. 7, pp. 39912. Date of Electronic Publication: 2017 Jan 03.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited

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Academic Journal

Intradermal delivery of DNA encoding HCV NS3 and perforin elicits robust cell-mediated immunity in mice and pigs.

  • Authors : Grubor-Bauk B; Virology Laboratory, Discipline of Surgery, University of Adelaide and Basil Hetzel Institute for Translational Medicine, Adelaide, SA, Australia.; Yu W

Subjects: Hepacivirus* ; Immunity, Cellular*; DNA, Viral/DNA, Viral/DNA, Viral/*genetics

  • Source: Gene therapy [Gene Ther] 2016 Jan; Vol. 23 (1), pp. 26-37. Date of Electronic Publication: 2015 Oct 01.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 9421525 Publication Model: Print-Electronic Cited

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Academic Journal

Coexpression of human perforin improves yeast-mediated delivery of DNA and mRNA to mammalian antigen-presenting cells.

  • Authors : Walch-Rückheim B; Department of Molecular and Cell Biology, Saarland University, Saarbrücken, Germany.; Medical Faculty, Junior Research Group for Virology and Immunology, Institute of Virology and Center of Human and Molecular Biology, Saarland University, Homburg Saar, Germany.

Subjects: Genetic Vectors* ; Saccharomyces cerevisiae*; Antigen-Presenting Cells/Antigen-Presenting Cells/Antigen-Presenting Cells/*metabolism

  • Source: Gene therapy [Gene Ther] 2016 Jan; Vol. 23 (1), pp. 103-7. Date of Electronic Publication: 2015 Aug 20.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 9421525 Publication Model: Print-Electronic Cited

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Academic Journal

Disruption of the open conductance in the β-tongue mutants of Cytolysin A.

  • Authors : Fahie MA; Molecular and Cellular Biology Program, University of Massachusetts Amherst, Amherst, MA, 01003, USA.; Department of Chemistry, University of Massachusetts Amherst, Amherst, MA, 01003, USA.

Subjects: Mutation*; Perforin/Perforin/Perforin/*chemistry ; Perforin/Perforin/Perforin/*metabolism

  • Source: Scientific reports [Sci Rep] 2018 Feb 28; Vol. 8 (1), pp. 3796. Date of Electronic Publication: 2018 Feb 28.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited

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Academic Journal

Novel function of perforin in negatively regulating CD4(+) T cell activation by affecting calcium signaling.

  • Authors : Bi E; Laboratory of Molecular Cell Biology, Institute of Biochemistry and Cell Biology, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai, China.; Huang C

Subjects: Calcium Signaling* ; Lymphocyte Activation*; CD4 Antigens/CD4 Antigens/CD4 Antigens/*metabolism

  • Source: Cell research [Cell Res] 2009 Jul; Vol. 19 (7), pp. 816-27.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 9425763 Publication Model: Print Cited Medium:

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  • 1-10 of  1,935 results for ""Perforin""