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The reversal of methotrexate toxicity by thymidine with maintenance of antitumour effects.

• Authors : Tattersall MH; Brown B; Frei E 3rd

Subjects: Leukemia L1210/Leukemia L1210/Leukemia L1210/*drug therapy ; Methotrexate/Methotrexate/Methotrexate/*therapeutic use ; Thymidine/Thymidine/Thymidine/*therapeutic use

• Source: Nature [Nature] 1975 Jan 17; Vol. 253 (5488), pp. 198-200.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 0410462 Publication Model: Print Cited Medium:

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Tumour lysis syndrome.

• Authors : Howard SC; Resonance, Memphis, TN, USA. .; Yeolyan Center for Hematology and Oncology, Yerevan, Armenia. .

Subjects: Tumor Lysis Syndrome*/Tumor Lysis Syndrome*/Tumor Lysis Syndrome*/physiopathology ; Tumor Lysis Syndrome*/Tumor Lysis Syndrome*/Tumor Lysis Syndrome*/etiology ; Tumor Lysis Syndrome*/Tumor Lysis Syndrome*/Tumor Lysis Syndrome*/diagnosis

• Source: Nature reviews. Disease primers [Nat Rev Dis Primers] 2024 Aug 22; Vol. 10 (1), pp. 58. Date of Electronic Publication: 2024 Aug 22.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101672103 Publication Model: Electronic Cited

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Dietary folate drives methionine metabolism to promote cancer development by stabilizing MAT IIA.

• Authors : Li JT; Fudan University Shanghai Cancer Center & Institutes of Biomedical Sciences; Cancer Institutes

Subjects: Folic Acid*/Folic Acid*/Folic Acid*/pharmacology ; Methionine Adenosyltransferase*/Methionine Adenosyltransferase*/Methionine Adenosyltransferase*/genetics ; Methionine Adenosyltransferase*/Methionine Adenosyltransferase*/Methionine Adenosyltransferase*/metabolism

• Source: Signal transduction and targeted therapy [Signal Transduct Target Ther] 2022 Jun 22; Vol. 7 (1), pp. 192. Date of Electronic Publication: 2022 Jun 22.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101676423 Publication Model: Electronic Cited

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Use of stable isotope-tagged thymidine and multi-isotope imaging mass spectrometry (MIMS) for quantification of human cardiomyocyte division.

• Authors : Yester, Jessie W.; Liu, Honghai; Gyngard, Frank

• Source: Nature Protocols. April, 2021, Vol. 16 Issue 4, p1995, 28 p.

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Folate metabolism: a re-emerging therapeutic target in haematological cancers

• Authors : Zarou, Martha M.; Vazquez, Alexei; Vignir Helgason, G.

• Source: Leukemia. June, 2021, Vol. 35 Issue 6, p1539, 13 p.

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Treatment and unmet needs in steroid-refractory acute graft-versus-host disease

• Authors : Malard, Florent; Huang, Xiao-Jun; Sim, Joycelyn P. Y.

• Source: Leukemia. May, 2020, Vol. 34 Issue 5, p1229, 12 p.

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Antithymidylate resistance enables transgene selection and cell survival for T cells in the presence of 5-fluorouracil and antifolates.

• Authors : Rushworth, D; Alpert, A; Santana-Carrero, R

• Source: Gene Therapy. February, 2016, Vol. 23 Issue 2, p119, 10 p.

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Efficient in vivo regulation of cytidine deaminase expression in the haematopoietic system using a doxycycline-inducible lentiviral vector system.

• Authors : Lachmann, N.; Brennig, S.; Pfaff, N.

• Source: Gene Therapy. March 1, 2013, Vol. 20 Issue 3, p298, 10 p.

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Does methotrexate improve TNF inhibitor drug survival in elderly patients with RA?

• Authors : Lahaye, Clément; Soubrier, Martin

• Source: Nature Reviews Rheumatology. July, 2020, Vol. 16 Issue 7, p353, 2 p.

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In vivo selection of human embryonic stem cell-derived cells expressing methotrexate-resistant dihydrofolate reductase.

• Authors : Gori, J.L.; Tian, X.; Swanson, D.

• Source: Gene Therapy. February 1, 2010, Vol. 17 Issue 2, p238, 12 p.

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