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Academic Journal

Myelin oligodendrocyte glycoprotein reactive Th17 cells drive Janus Kinase 1 dependent transcriptional reprogramming in astrocytes and alter cell surface cytokine receptor profiles during experimental autoimmune encephalomyelitis.

  • Authors : Milne SM; Department of Microbiology, Immunology, and Cell Biology, West Virginia University, Morgantown, WV, 26506, USA.; Lahiri A

Subjects: Encephalomyelitis, Autoimmune, Experimental*/Encephalomyelitis, Autoimmune, Experimental*/Encephalomyelitis, Autoimmune, Experimental*/metabolism ; Encephalomyelitis, Autoimmune, Experimental*/Encephalomyelitis, Autoimmune, Experimental*/Encephalomyelitis, Autoimmune, Experimental*/immunology ; Encephalomyelitis, Autoimmune, Experimental*/Encephalomyelitis, Autoimmune, Experimental*/Encephalomyelitis, Autoimmune, Experimental*/pathology

  • Source: Scientific reports [Sci Rep] 2024 Jun 07; Vol. 14 (1), pp. 13146. Date of Electronic Publication: 2024 Jun 07.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited

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Academic Journal

Spatial proteomics identifies JAKi as treatment for a lethal skin disease.

  • Authors : Nordmann TM; Department of Proteomics and Signal Transduction; Max Planck Institute of Biochemistry, Martinsried, Germany. .

Subjects: Janus Kinase 1*/Janus Kinase 1*/Janus Kinase 1*/metabolism ; Janus Kinase 1*/Janus Kinase 1*/Janus Kinase 1*/antagonists & inhibitors ; Janus Kinase Inhibitors*/Janus Kinase Inhibitors*/Janus Kinase Inhibitors*/administration & dosage

  • Source: Nature [Nature] 2024 Nov; Vol. 635 (8040), pp. 1001-1009. Date of Electronic Publication: 2024 Oct 16.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 0410462 Publication Model: Print-Electronic Cited

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Academic Journal

Potential therapeutic effects of IL28RA inhibition on acute myocardial infarction through phosphorylated JAK1/STAT1 signaling pathways.

  • Authors : Gong G; Department of Geriatrics, Affiliated Hospital of Medical School, Jinling Hospital, Nanjing University, Nanjing, 210002, China.; Chen X

Subjects: Myocardial Infarction*/Myocardial Infarction*/Myocardial Infarction*/metabolism ; Myocardial Infarction*/Myocardial Infarction*/Myocardial Infarction*/pathology ; Janus Kinase 1*/Janus Kinase 1*/Janus Kinase 1*/metabolism

  • Source: Scientific reports [Sci Rep] 2024 Dec 20; Vol. 14 (1), pp. 30576. Date of Electronic Publication: 2024 Dec 20.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited

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Academic Journal

RBM12 drives PD-L1-mediated immune evasion in hepatocellular carcinoma by increasing JAK1 mRNA translation.

  • Authors : Han H; Department of Gastroenterology, The Affiliated Taizhou People's Hospital of Nanjing Medical University, Taizhou School of Clinical Medicine, Nanjing Medical University, Taizhou, Jiangsu, 225300, China.; Shi Q

Subjects: Carcinoma, Hepatocellular*/Carcinoma, Hepatocellular*/Carcinoma, Hepatocellular*/genetics ; Carcinoma, Hepatocellular*/Carcinoma, Hepatocellular*/Carcinoma, Hepatocellular*/pathology ; Carcinoma, Hepatocellular*/Carcinoma, Hepatocellular*/Carcinoma, Hepatocellular*/immunology

  • Source: Oncogene [Oncogene] 2024 Oct; Vol. 43 (41), pp. 3062-3077. Date of Electronic Publication: 2024 Aug 26.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 8711562 Publication Model: Print-Electronic Cited

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Academic Journal

Cellular precision modulation of JAK1: tailoring therapies for allergic lung inflammation.

  • Authors : Yan X; Research Unit Adipocytes & Metabolism (ADM), Helmholtz Diabetes Center, Helmholtz Zentrum München, German Research Center for Environmental Health GmbH, 85764, Neuherberg, Germany.; German Center for Diabetes Research (DZD), 85764, Neuherberg, Germany.

Subjects: Janus Kinase 1*/Janus Kinase 1*/Janus Kinase 1*/genetics ; Janus Kinase 1*/Janus Kinase 1*/Janus Kinase 1*/immunology ; Pneumonia*/Pneumonia*/Pneumonia*/genetics

  • Source: Signal transduction and targeted therapy [Signal Transduct Target Ther] 2024 Jun 17; Vol. 9 (1), pp. 147. Date of Electronic Publication: 2024 Jun Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101676423 Publication Model: Electronic Cited

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Academic Journal

Mechanism of TCONS_00147848 regulating apoptosis of nasal mucosa cells and alleviating allergic rhinitis through FOSL2-mediated JAK/STAT3 signaling pathway.

  • Authors : Huang H; ENT Department, Inner Mongolia People's Hospital, Hohhot Inner Mongolia Autonomous Region, Hohhot, 010017, China.; Ren Y

Subjects: Apoptosis*; Fos-Related Antigen-2/Fos-Related Antigen-2/Fos-Related Antigen-2/*antagonists & inhibitors ; Janus Kinase 1/Janus Kinase 1/Janus Kinase 1/*metabolism

  • Source: Scientific reports [Sci Rep] 2021 Aug 06; Vol. 11 (1), pp. 15991. Date of Electronic Publication: 2021 Aug 06.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited

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Academic Journal

Computer aided designing of novel pyrrolopyridine derivatives as JAK1 inhibitors.

  • Authors : Keretsu S; Department of Biomedical Sciences, College of Medicine, Chosun University, 375 Seosuk-dong, Dong-gu, Gwangju, 501-759, Republic of Korea.; Ghosh S

Subjects: Drug Design*; Janus Kinase 1/Janus Kinase 1/Janus Kinase 1/*chemistry ; Pyridines/Pyridines/Pyridines/*chemistry

  • Source: Scientific reports [Sci Rep] 2021 Nov 29; Vol. 11 (1), pp. 23051. Date of Electronic Publication: 2021 Nov 29.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited

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Academic Journal

Low-dose radiation decreases tumor progression via the inhibition of the JAK1/STAT3 signaling axis in breast cancer cell lines.

  • Authors : Kaushik N; Department of Life Science, Research Institute for Natural Sciences, Hanyang University, Seoul 04763, Republic of Korea.; Kim MJ

Subjects: Gene Expression Regulation, Neoplastic*; Breast Neoplasms/Breast Neoplasms/Breast Neoplasms/*radiotherapy ; Epithelial-Mesenchymal Transition/Epithelial-Mesenchymal Transition/Epithelial-Mesenchymal Transition/*radiation effects

  • Source: Scientific reports [Sci Rep] 2017 Feb 27; Vol. 7, pp. 43361. Date of Electronic Publication: 2017 Feb 27.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited

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Academic Journal

The JAK1/STAT3/SOCS3 axis in bone development, physiology, and pathology.

  • Authors : Sims NA; St. Vincent's Institute of Medical Research, and Department of Medicine at St. Vincent's Hospital, The University of Melbourne, Parkville, VIC, Australia. .

Subjects: Bone Development* ; Signal Transduction*; Bone and Bones/Bone and Bones/Bone and Bones/*pathology

  • Source: Experimental & molecular medicine [Exp Mol Med] 2020 Aug; Vol. 52 (8), pp. 1185-1197. Date of Electronic Publication: 2020 Aug 13.Publisher: Nature Publishing Group Country of Publication: United States NLM ID: 9607880 Publication Model: Print-Electronic

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Academic Journal

microRNA-23a, -27a and -24 synergistically regulate JAK1/Stat3 cascade and serve as novel therapeutic targets in human acute erythroid leukemia.

  • Authors : Su R; Department of Biochemistry, State Key Laboratory of Medical Molecular Biology, Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences (CAMS) & Peking Union Medical College (PUMC), Beijing, People's Republic of China.; Department of Cancer Biology, College of Medicine, University of Cincinnati, Cincinnati, OH, USA.

Subjects: Gene Expression Regulation, Leukemic*/Gene Expression Regulation, Leukemic*/Gene Expression Regulation, Leukemic*/drug effects ; Signal Transduction*; Janus Kinase 1/Janus Kinase 1/Janus Kinase 1/*metabolism Acute erythroleukemia

  • Source: Oncogene [Oncogene] 2016 Nov 17; Vol. 35 (46), pp. 6001-6014. Date of Electronic Publication: 2016 Apr 18.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 8711562 Publication Model: Print-Electronic Cited

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  • 1-10 of  376 results for ""Janus Kinase 1""