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Academic Journal

TIGAR coordinates senescence-associated secretory phenotype via lysosome repositioning and α-tubulin deacetylation.

  • Authors : Nam HY; Department of Biochemistry and Molecular Biology, Brain Korea 21 project, Asan Medical Center, University of Ulsan College of Medicine, Seoul, 05505, South Korea. .; Park SH

Subjects: Cellular Senescence* ; Lysosomes*/Lysosomes*/Lysosomes*/metabolism ; Tubulin*/Tubulin*/Tubulin*/metabolism

  • Source: Experimental & molecular medicine [Exp Mol Med] 2024 Dec; Vol. 56 (12), pp. 2726-2738. Date of Electronic Publication: 2024 Dec 04.Publisher: Nature Publishing Group Country of Publication: United States NLM ID: 9607880 Publication Model: Print-Electronic

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Academic Journal

Nuclear receptor E75/NR1D2 promotes tumor malignant transformation by integrating Hippo and Notch pathways.

  • Authors : Wang X; Westlake Laboratory of Life Sciences and Biomedicine, Hangzhou, 310024, Zhejiang, China. .; School of Life Sciences, Westlake University, Hangzhou, 310024, Zhejiang, China. .

Subjects: Receptors, Notch*/Receptors, Notch*/Receptors, Notch*/metabolism ; Receptors, Notch*/Receptors, Notch*/Receptors, Notch*/genetics ; Drosophila Proteins*/Drosophila Proteins*/Drosophila Proteins*/metabolism

  • Source: The EMBO journal [EMBO J] 2024 Dec; Vol. 43 (24), pp. 6336-6363. Date of Electronic Publication: 2024 Nov 08.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 8208664 Publication Model: Print-Electronic Cited

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Academic Journal

Recruitment of autophagy initiator TAX1BP1 advances aggrephagy from cargo collection to sequestration.

  • Authors : Bauer B; Max Perutz Labs, Vienna Biocenter Campus (VBC), Dr.-Bohr-Gasse 9, 1030, Vienna, Austria.; University of Vienna, Max Perutz Labs, Department of Biochemistry and Cell Biology, Dr.-Bohr-Gasse 9, 1030, Vienna, Austria.

Subjects: Autophagy* ; Autophagosomes*/Autophagosomes*/Autophagosomes*/metabolism ; Protein Serine-Threonine Kinases*/Protein Serine-Threonine Kinases*/Protein Serine-Threonine Kinases*/metabolism

  • Source: The EMBO journal [EMBO J] 2024 Dec; Vol. 43 (23), pp. 5910-5940. Date of Electronic Publication: 2024 Oct 24.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 8208664 Publication Model: Print-Electronic Cited

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Academic Journal

KRAS-mediated upregulation of CIP2A promotes suppression of PP2A-B56α to initiate pancreatic cancer development.

  • Authors : Tinsley SL; Purdue University Interdisciplinary Life Sciences Program (PULSe), Purdue University, West Lafayette, IN, USA.; Department of Biological Sciences, Purdue University, West Lafayette, IN, USA.

Subjects: Protein Phosphatase 2*/Protein Phosphatase 2*/Protein Phosphatase 2*/metabolism ; Protein Phosphatase 2*/Protein Phosphatase 2*/Protein Phosphatase 2*/genetics ; Proto-Oncogene Proteins p21(ras)*/Proto-Oncogene Proteins p21(ras)*/Proto-Oncogene Proteins p21(ras)*/genetics

  • Source: Oncogene [Oncogene] 2024 Dec; Vol. 43 (50), pp. 3673-3687. Date of Electronic Publication: 2024 Oct 23.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 8711562 Publication Model: Print-Electronic Cited

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Academic Journal

Glutamine sensing licenses cholesterol synthesis.

Subjects: Cholesterol*/Cholesterol*/Cholesterol*/metabolism ; Cholesterol*/Cholesterol*/Cholesterol*/biosynthesis ; Glutamine*/Glutamine*/Glutamine*/metabolism

  • Source: The EMBO journal [EMBO J] 2024 Dec; Vol. 43 (23), pp. 5837-5856. Date of Electronic Publication: 2024 Oct 21.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 8208664 Publication Model: Print-Electronic Cited

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Academic Journal

Circulating YKL-40 levels but not CHI3L1 or TRIB1 gene variants predict long-term outcomes in patients with angiographically confirmed multivessel coronary artery disease.

  • Authors : Chou HH; Division of Cardiology, Department of Internal Medicine, Taipei Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation, 289 Jianguo Road, Xindian District, New Taipei City, 23142, Taiwan.; School of Medicine, Tzu Chi University, Hualien, Taiwan.

Subjects: Chitinase-3-Like Protein 1*/Chitinase-3-Like Protein 1*/Chitinase-3-Like Protein 1*/genetics ; Chitinase-3-Like Protein 1*/Chitinase-3-Like Protein 1*/Chitinase-3-Like Protein 1*/blood ; Coronary Artery Disease*/Coronary Artery Disease*/Coronary Artery Disease*/genetics

  • Source: Scientific reports [Sci Rep] 2024 Nov 27; Vol. 14 (1), pp. 29416. Date of Electronic Publication: 2024 Nov 27.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited

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Academic Journal

Circular RNA HIPK3 mediates epithelial-mesenchymal transition of retinal pigment epithelial cells by sponging multiple microRNAs.

  • Authors : Feng Y; Department of Ophthalmology, Yixing Eye Hospital, Wuxi School of Medicine, Jiangnan University, Intersection of Hongta Road Kang Ming Road, Yicheng Street, Yixing, 214200, Jiangsu, China.; Yang F

Subjects: Epithelial-Mesenchymal Transition*/Epithelial-Mesenchymal Transition*/Epithelial-Mesenchymal Transition*/genetics ; MicroRNAs*/MicroRNAs*/MicroRNAs*/genetics ; MicroRNAs*/MicroRNAs*/MicroRNAs*/metabolism

  • Source: Scientific reports [Sci Rep] 2024 Nov 21; Vol. 14 (1), pp. 28872. Date of Electronic Publication: 2024 Nov 21.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited

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Academic Journal

TIPE2 inhibits melanoma progression through MEK/ERK signaling.

  • Authors : Gao X; School of Clinical Medicine, Weifang Medical University, Weifang, China.; Li Y

Subjects: Melanoma*/Melanoma*/Melanoma*/metabolism ; Melanoma*/Melanoma*/Melanoma*/pathology ; Melanoma*/Melanoma*/Melanoma*/genetics

  • Source: Scientific reports [Sci Rep] 2024 Nov 12; Vol. 14 (1), pp. 27736. Date of Electronic Publication: 2024 Nov 12.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited

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Academic Journal

Intestinal epithelial Gasdermin C is induced by IL-4R/STAT6 signaling but is dispensable for gut immune homeostasis.

  • Authors : Gámez-Belmonte R; Department of Medicine 1, Friedrich-Alexander-Universität Erlangen-Nürnberg (FAU) and Universitätsklinikum Erlangen, Erlangen, Germany.; Wagner Y

Subjects: STAT6 Transcription Factor*/STAT6 Transcription Factor*/STAT6 Transcription Factor*/metabolism ; STAT6 Transcription Factor*/STAT6 Transcription Factor*/STAT6 Transcription Factor*/genetics ; Homeostasis*

  • Source: Scientific reports [Sci Rep] 2024 Nov 03; Vol. 14 (1), pp. 26522. Date of Electronic Publication: 2024 Nov 03.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited

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Academic Journal

Ehbp1 orchestrates orderly sorting of Wnt/Wingless to the basolateral and apical cell membranes.

  • Authors : Gao Y; Ministry of Education Key Laboratory of Cell Proliferation and Differentiation, School of Life Sciences, Peking University, Beijing, 100871, China.; Peking-Tsinghua Center for Life Sciences, Academy for Advanced Interdisciplinary Studies, Peking University, Beijing, 100871, China.

Subjects: Drosophila Proteins*/Drosophila Proteins*/Drosophila Proteins*/metabolism ; Drosophila Proteins*/Drosophila Proteins*/Drosophila Proteins*/genetics ; Cell Membrane*/Cell Membrane*/Cell Membrane*/metabolism

  • Source: EMBO reports [EMBO Rep] 2024 Nov; Vol. 25 (11), pp. 5053-5079. Date of Electronic Publication: 2024 Oct 14.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 100963049 Publication Model: Print-Electronic

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  • 1-10 of  613 results for ""Intracellular Signaling Peptides and Proteins genetics""