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Academic Journal

PLK1 overexpression suppresses homologous recombination and confers cellular sensitivity to PARP inhibition.

  • Authors : Pae S; Department of Frontier Medicine, Institute of Medical Science, Graduate School of Medicine, St. Marianna University, Kawasaki, 2168511, Japan.; Sedukhina AS

Subjects: Polo-Like Kinase 1* ; Cell Cycle Proteins*/Cell Cycle Proteins*/Cell Cycle Proteins*/metabolism ; Cell Cycle Proteins*/Cell Cycle Proteins*/Cell Cycle Proteins*/genetics

  • Source: Scientific reports [Sci Rep] 2024 Dec 28; Vol. 14 (1), pp. 31276. Date of Electronic Publication: 2024 Dec 28.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited

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Academic Journal

Structural insights into the mechanism of DNA branch migration during homologous recombination in bacteria.

  • Authors : Rosa LT; Structure and Function of Bacterial Nanomachines-Institut Européen de Chimie et Biologie, Microbiologie fondamentale et pathogénicité, UMR 5234, CNRS, University of Bordeaux, 2 rue Robert Escarpit, 33600, Pessac, France.; Departamento de Bioquímica e Biologia Tecidual. Laboratório de Bioquímica de Complexos Bacterianos. Instituto de Biologia. Universidade Estadual de Campinas (UNICAMP), Monteiro Lobato, 255, Campinas, 13083-862, Brasil.

Subjects: Homologous Recombination* ; DNA Helicases*/DNA Helicases*/DNA Helicases*/metabolism ; DNA Helicases*/DNA Helicases*/DNA Helicases*/chemistry

  • Source: The EMBO journal [EMBO J] 2024 Dec; Vol. 43 (23), pp. 6180-6198. Date of Electronic Publication: 2024 Oct 18.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 8208664 Publication Model: Print-Electronic Cited

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Academic Journal

Promotion of DNA end resection by BRCA1-BARD1 in homologous recombination.

  • Authors : Salunkhe S; Department of Biochemistry & Structural Biology and Greehey Children's Cancer Research Institute, University of Texas Health Science Center at San Antonio, San Antonio, TX, USA.; Daley JM

Subjects: BRCA1 Protein*/BRCA1 Protein*/BRCA1 Protein*/metabolism ; BRCA1 Protein*/BRCA1 Protein*/BRCA1 Protein*/genetics ; DNA Breaks, Double-Stranded*

  • Source: Nature [Nature] 2024 Oct; Vol. 634 (8033), pp. 482-491. Date of Electronic Publication: 2024 Sep 11.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 0410462 Publication Model: Print-Electronic Cited

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Academic Journal

WWOX binds MERIT40 and modulates its function in homologous recombination, implications in breast cancer.

  • Authors : Taouis K; Service de génétique, unité de pharmacogénomique, Institut Curie, 26 rue d'Ulm, Paris, France.; Paris Sciences Lettres Research University, Paris, France.

Subjects: Breast Neoplasms*/Breast Neoplasms*/Breast Neoplasms*/genetics ; Homologous Recombination*; Female

  • Source: Cancer gene therapy [Cancer Gene Ther] 2023 Aug; Vol. 30 (8), pp. 1144-1155. Date of Electronic Publication: 2023 May 29.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 9432230 Publication Model: Print-Electronic Cited

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Academic Journal

Structural insights into BCDX2 complex function in homologous recombination.

  • Authors : Rawal Y; Department of Biochemistry & Structural Biology and Greehey Children's Cancer Research Institute, University of Texas Health Science Center at San Antonio, San Antonio, TX, USA.; Jia L

Subjects: DNA-Binding Proteins*/DNA-Binding Proteins*/DNA-Binding Proteins*/chemistry ; DNA-Binding Proteins*/DNA-Binding Proteins*/DNA-Binding Proteins*/metabolism ; DNA-Binding Proteins*/DNA-Binding Proteins*/DNA-Binding Proteins*/ultrastructure

  • Source: Nature [Nature] 2023 Jul; Vol. 619 (7970), pp. 640-649. Date of Electronic Publication: 2023 Jun 21.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 0410462 Publication Model: Print-Electronic Cited

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Academic Journal

Identification of molecular subtypes and prognostic signature for hepatocellular carcinoma based on genes associated with homologous recombination deficiency.

  • Authors : Lin H; Guangxi University of Chinese Medicine, Nanning, 530200, China.; Department of Laboratory, The First Affiliated Hospital of Guangxi University of Chinese Medicine, Nanning, 530023, China.

Subjects: Biomarkers, Tumor* ; Homologous Recombination* ; Transcriptome*

  • Source: Scientific reports [Sci Rep] 2021 Dec 15; Vol. 11 (1), pp. 24022. Date of Electronic Publication: 2021 Dec 15.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited

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Academic Journal

BARD1 reads H2A lysine 15 ubiquitination to direct homologous recombination.

  • Authors : Becker JR; Medical Research Council (MRC) Molecular Haematology Unit, Weatherall Institute of Molecular Medicine, University of Oxford, Oxford, UK.; Wellcome Centre for Human Genetics, University of Oxford, Oxford, UK.

Subjects: Homologous Recombination* ; Ubiquitination*; Lysine/Lysine/Lysine/*chemistry

  • Source: Nature [Nature] 2021 Aug; Vol. 596 (7872), pp. 433-437. Date of Electronic Publication: 2021 Jul 28.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 0410462 Publication Model: Print-Electronic Cited

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Academic Journal

A first-in-class Polymerase Theta Inhibitor selectively targets Homologous-Recombination-Deficient Tumors.

  • Authors : Zhou J; Department of Radiation Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA, USA.; Gelot C

Subjects: Homologous Recombination*/Homologous Recombination*/Homologous Recombination*/genetics ; Ovarian Neoplasms*/Ovarian Neoplasms*/Ovarian Neoplasms*/drug therapy; Adenosine Triphosphatases/Adenosine Triphosphatases/Adenosine Triphosphatases/genetics

  • Source: Nature cancer [Nat Cancer] 2021 Jun; Vol. 2 (6), pp. 598-610. Date of Electronic Publication: 2021 Jun 17.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101761119 Publication Model: Print-Electronic

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Academic Journal

Break-induced replication orchestrates resection-dependent template switching.

  • Authors : Zhang T; Department of Cancer Biology, Penn Center for Genome Integrity, Basser Center for BRCA, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.; Rawal Y

Subjects: DNA Breaks, Double-Stranded* ; DNA Repair* ; DNA Replication*

  • Source: Nature [Nature] 2023 Jul; Vol. 619 (7968), pp. 201-208. Date of Electronic Publication: 2023 Jun 14.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 0410462 Publication Model: Print-Electronic Cited

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Academic Journal

RBX1 prompts degradation of EXO1 to limit the homologous recombination pathway of DNA double-strand break repair in G1 phase.

  • Authors : Xie Y; Department of Radiation Toxicology and Oncology, Beijing Institute of Radiation Medicine, 100850, Beijing, China.; Key Laboratory of Molecular Epidemiology of Hunan Province, School of Medicine, Hunan Normal University, 410013, Changsha, China.

Subjects: DNA Breaks, Double-Stranded* ; DNA Repair* ; G1 Phase*

  • Source: Cell death and differentiation [Cell Death Differ] 2020 Apr; Vol. 27 (4), pp. 1383-1397. Date of Electronic Publication: 2019 Sep 27.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 9437445 Publication Model: Print-Electronic Cited

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  • 1-10 of  6,938 results for ""HOMOLOGOUS recombination""