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Gene-edited healthy donor CAR T cells show superior anti-tumour activity compared to CAR T cells derived from patients with lymphoma in an in vivo model of high-grade lymphoma.

  • Authors : Graham CE; Faculty of Life Sciences and Medicine, School of Cancer and Pharmaceutical Sciences, King's College London, London, United Kingdom. .; King's College Hospital NHS Foundation Trust, London, United Kingdom. .

Subjects: Gene Editing*; Antigens, CD19/Antigens, CD19/Antigens, CD19/*immunology ; Immunotherapy, Adoptive/Immunotherapy, Adoptive/Immunotherapy, Adoptive/*methods

  • Source: Leukemia [Leukemia] 2021 Dec; Vol. 35 (12), pp. 3581-3584. Date of Electronic Publication: 2021 Jun 18.Publisher: Nature Publishing Group, Specialist Journals Country of Publication: England NLM ID: 8704895 Publication Model:

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Tracking T-cell immune reconstitution after TCRαβ/CD19-depleted hematopoietic cells transplantation in children.

  • Authors : Zvyagin IV; Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Science, Moscow, Russia.; CEITEC MU, Masaryk University, Brno, Czech republic.

Subjects: Antigens, CD19* ; Graft Survival* ; Receptors, Antigen, T-Cell, alpha-beta*

  • Source: Leukemia [Leukemia] 2017 May; Vol. 31 (5), pp. 1145-1153. Date of Electronic Publication: 2016 Nov 04.Publisher: Nature Publishing Group, Specialist Journals Country of Publication: England NLM ID: 8704895 Publication Model:

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TCRα rearrangements identify a subgroup of NKL-deregulated adult T-ALLs associated with favorable outcome.

  • Authors : Villarese P; Université Paris Descartes Sorbonne Cité, Institut Necker Enfants-Malades (INEM), Institut National de Recherche Médicale (INSERM) U1151, Paris, France.; Laboratory of Onco-Hematology, Assistance Publique-Hôpitaux de Paris (AP-HP), Hôpital Necker Enfants-Malades, Paris, France.

Subjects: Homeodomain Proteins/Homeodomain Proteins/Homeodomain Proteins/*metabolism ; Leukemia-Lymphoma, Adult T-Cell/Leukemia-Lymphoma, Adult T-Cell/Leukemia-Lymphoma, Adult T-Cell/*metabolism ; Precursor T-Cell Lymphoblastic Leukemia-Lymphoma/Precursor T-Cell Lymphoblastic Leukemia-Lymphoma/Precursor T-Cell Lymphoblastic Leukemia-Lymphoma/*metabolism

  • Source: Leukemia [Leukemia] 2018 Jan; Vol. 32 (1), pp. 61-71. Date of Electronic Publication: 2017 Jun 08.Publisher: Nature Publishing Group, Specialist Journals Country of Publication: England NLM ID: 8704895 Publication Model:

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The presence and longevity of peripherally expanded donor-derived TCRalphabeta+ mature T lymphocyte clones after allogeneic bone marrow transplantation for adult myeloid leukemias.

  • Authors : Saitoh H; Department of Internal Medicine III, Akita University School of Medicine, Akita, Japan.; Hirokawa M

Subjects: Bone Marrow Transplantation* ; Transplantation Chimera*; Leukemia, Myeloid/Leukemia, Myeloid/Leukemia, Myeloid/*therapy

  • Source: Leukemia [Leukemia] 2003 Aug; Vol. 17 (8), pp. 1626-35.Publisher: Nature Publishing Group, Specialist Journals Country of Publication: England NLM ID: 8704895 Publication Model: Print

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Molecular analysis of T-cell receptor transcripts in a human T-cell leukemia bearing a t(1;14) and an inv(7); cell surface expression of a TCR-beta chain in the absence of alpha chain.

  • Authors : Bernard O; Institut National de la Santé et de la Recherche Médicale (INSERM)-U.301, Paris, France.; Groettrup M

Subjects: Chromosome Inversion*; Chromosomes, Human, Pair 1/Chromosomes, Human, Pair 1/Chromosomes, Human, Pair 1/*physiology ; Chromosomes, Human, Pair 14/Chromosomes, Human, Pair 14/Chromosomes, Human, Pair 14/*physiology

  • Source: Leukemia [Leukemia] 1993 Oct; Vol. 7 (10), pp. 1645-53.Publisher: Nature Publishing Group, Specialist Journals Country of Publication: England NLM ID: 8704895 Publication Model: Print

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Regulation of human T cell receptor beta gene expression by Ets-1.

Subjects: Transcription Factors*; Gene Expression Regulation/Gene Expression Regulation/Gene Expression Regulation/*genetics ; Proto-Oncogene Proteins/Proto-Oncogene Proteins/Proto-Oncogene Proteins/*physiology

  • Source: Leukemia [Leukemia] 1993 Aug; Vol. 7 Suppl 2, pp. S55-60.Publisher: Nature Publishing Group, Specialist Journals Country of Publication: England NLM ID: 8704895 Publication Model: Print

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Structural basis of Ets1 activation by Runx1.

  • Authors : Shrivastava T; Eppley Institute for Research in Cancer and Allied Diseases, University of Nebraska Medical Center, Omaha, NE, USA.; Mino K

Subjects: Core Binding Factor Alpha 2 Subunit/Core Binding Factor Alpha 2 Subunit/Core Binding Factor Alpha 2 Subunit/*metabolism ; Proto-Oncogene Protein c-ets-1/Proto-Oncogene Protein c-ets-1/Proto-Oncogene Protein c-ets-1/*metabolism ; Receptors, Antigen, T-Cell, alpha-beta/Receptors, Antigen, T-Cell, alpha-beta/Receptors, Antigen, T-Cell, alpha-beta/*metabolism

  • Source: Leukemia [Leukemia] 2014 Oct; Vol. 28 (10), pp. 2040-8. Date of Electronic Publication: 2014 Mar 20.Publisher: Nature Publishing Group, Specialist Journals Country of Publication: England NLM ID: 8704895 Publication Model:

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T-cell receptor Vbeta CDR3 oligoclonality frequently occurs in childhood refractory cytopenia (MDS-RC) and severe aplastic anemia.

  • Authors : de Vries AC; Department of Pediatric Oncology/Hematology, Erasmus University Medical Center-Sophia Children's Hospital, Rotterdam, The Netherlands.; Langerak AW

Subjects: Anemia, Aplastic/Anemia, Aplastic/Anemia, Aplastic/*genetics ; Anemia, Refractory/Anemia, Refractory/Anemia, Refractory/*genetics ; Myelodysplastic Syndromes/Myelodysplastic Syndromes/Myelodysplastic Syndromes/*genetics

  • Source: Leukemia [Leukemia] 2008 Jun; Vol. 22 (6), pp. 1170-4. Date of Electronic Publication: 2008 Mar 06.Publisher: Nature Publishing Group, Specialist Journals Country of Publication: England NLM ID: 8704895 Publication Model:

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  • 1-10 of  44 results for ""Receptors, Antigen, T-Cell, alpha-beta""