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Academic Journal

A widespread role for SLC transmembrane transporters in resistance to cytotoxic drugs.

  • Authors : Girardi E; CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences, Vienna, Austria.; César-Razquin A

Subjects: Drug Resistance/Drug Resistance/Drug Resistance/*genetics ; Solute Carrier Proteins/Solute Carrier Proteins/Solute Carrier Proteins/*metabolism; Amino Acid Transport Systems, Neutral/Amino Acid Transport Systems, Neutral/Amino Acid Transport Systems, Neutral/genetics

  • Source: Nature chemical biology [Nat Chem Biol] 2020 Apr; Vol. 16 (4), pp. 469-478. Date of Electronic Publication: 2020 Mar 09.Publisher: Nature Pub. Group Country of Publication: United States NLM ID: 101231976 Publication Model: Print-Electronic

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Academic Journal

The RESOLUTE consortium: unlocking SLC transporters for drug discovery.

Subjects: Drug Discovery/Drug Discovery/Drug Discovery/*methods ; Pharmaceutical Preparations/Pharmaceutical Preparations/Pharmaceutical Preparations/*metabolism ; Solute Carrier Proteins/Solute Carrier Proteins/Solute Carrier Proteins/*metabolism

  • Source: Nature reviews. Drug discovery [Nat Rev Drug Discov] 2020 Jul; Vol. 19 (7), pp. 429-430.Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101124171 Publication Model: Print Cited Medium:

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Academic Journal

Interdomain-linkers control conformational transitions in the SLC23 elevator transporter UraA.

  • Authors : Kuhn BT; Institute of Biochemistry, Biocenter, Goethe University Frankfurt, Frankfurt am Main, Germany.; Max Planck Institute of Molecular Cell Biology and Genetics, Dresden, Germany.

Subjects: Bacterial Proteins*/Bacterial Proteins*/Bacterial Proteins*/metabolism ; Bacterial Proteins*/Bacterial Proteins*/Bacterial Proteins*/chemistry; Protein Conformation

  • Source: Nature communications [Nat Commun] 2024 Aug 30; Vol. 15 (1), pp. 7518. Date of Electronic Publication: 2024 Aug 30.Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium:

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The combination of genomic offset and niche modelling provides insights into climate change-driven vulnerability.

  • Authors : Chen Y; Key Laboratory of Zoological Systematics and Evolution, Institute of Zoology, Chinese Academy of Sciences, Beijing, China.; College of Life Sciences, University of Chinese Academy of Sciences, Beijing, China.

Subjects: Climate Change* ; Ecosystem*; Animals

  • Source: Nature communications [Nat Commun] 2022 Aug 16; Vol. 13 (1), pp. 4821. Date of Electronic Publication: 2022 Aug 16.Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium:

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Academic Journal

Role of bile acids and their receptors in gastrointestinal and hepatic pathophysiology.

  • Authors : Fuchs CD; Hans Popper Laboratory of Molecular Hepatology, Division of Gastroenterology and Hepatology, Department of Internal Medicine III, Medical University of Vienna, Vienna, Austria.; Trauner M

Subjects: Cholestasis*/Cholestasis*/Cholestasis*/metabolism ; Non-alcoholic Fatty Liver Disease*/Non-alcoholic Fatty Liver Disease*/Non-alcoholic Fatty Liver Disease*/metabolism; Bile Acids and Salts/Bile Acids and Salts/Bile Acids and Salts/metabolism

  • Source: Nature reviews. Gastroenterology & hepatology [Nat Rev Gastroenterol Hepatol] 2022 Jul; Vol. 19 (7), pp. 432-450. Date of Electronic Publication: 2022 Feb 14.Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101500079 Publication Model: Print-Electronic Cited

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Academic Journal

The GFP thermal shift assay for screening ligand and lipid interactions to solute carrier transporters.

  • Authors : Chatzikyriakidou Y; Department of Biochemistry and Biophysics, Stockholm University, Stockholm, Sweden.; Ahn DH

Subjects: High-Throughput Screening Assays*; Carrier Proteins/Carrier Proteins/Carrier Proteins/*metabolism ; Lipids/Lipids/Lipids/*chemistry

  • Source: Nature protocols [Nat Protoc] 2021 Dec; Vol. 16 (12), pp. 5357-5376. Date of Electronic Publication: 2021 Oct 27.Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101284307 Publication Model: Print-Electronic Cited

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A machine learning-based chemoproteomic approach to identify drug targets and binding sites in complex proteomes.

  • Authors : Piazza I; ETH Zürich, Institute of Molecular Systems Biology, Department of Biology, Otto-Stern-Weg 3, 8093, Zürich, Switzerland.; Biognosys AG, Wagistrasse 21, 8952, Schlieren, Switzerland.

Subjects: Machine Learning* ; Proteome*; Drug Delivery Systems/Drug Delivery Systems/Drug Delivery Systems/*methods

  • Source: Nature communications [Nat Commun] 2020 Aug 21; Vol. 11 (1), pp. 4200. Date of Electronic Publication: 2020 Aug 21.Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium:

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Epistasis-driven identification of SLC25A51 as a regulator of human mitochondrial NAD import.

  • Authors : Girardi E; CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences, Vienna, Austria.; Agrimi G

Subjects: Epistasis, Genetic*; Mitochondria/Mitochondria/Mitochondria/*metabolism ; NAD/NAD/NAD/*metabolism

  • Source: Nature communications [Nat Commun] 2020 Dec 01; Vol. 11 (1), pp. 6145. Date of Electronic Publication: 2020 Dec 01.Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium:

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  • 1-8 of  8 results for ""Solute Carrier Proteins""