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Academic Journal

Death by TNF: a road to inflammation.

  • Authors : van Loo G; Center for Inflammation Research, VIB, Ghent, Belgium. .; Department of Biomedical Molecular Biology, Ghent University, Ghent, Belgium. .

Subjects: Tumor Necrosis Factor-alpha* ; Inflammation*/Inflammation*/Inflammation*/drug therapy; Humans

  • Source: Nature reviews. Immunology [Nat Rev Immunol] 2023 May; Vol. 23 (5), pp. 289-303. Date of Electronic Publication: 2022 Nov 15.Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101124169 Publication Model: Print-Electronic Cited

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Academic Journal

TBK1-associated adapters TANK and AZI2 protect mice against TNF-induced cell death and severe autoinflammatory diseases.

  • Authors : Ujevic A; Laboratory of Immunity & Cell Communication, Division BIOCEV, First Faculty of Medicine, Charles University, Vestec, Czech Republic.; Knizkova D

Subjects: Protein Serine-Threonine Kinases*/Protein Serine-Threonine Kinases*/Protein Serine-Threonine Kinases*/metabolism ; Protein Serine-Threonine Kinases*/Protein Serine-Threonine Kinases*/Protein Serine-Threonine Kinases*/genetics ; Tumor Necrosis Factor-alpha*/Tumor Necrosis Factor-alpha*/Tumor Necrosis Factor-alpha*/metabolism

  • Source: Nature communications [Nat Commun] 2024 Nov 19; Vol. 15 (1), pp. 10013. Date of Electronic Publication: 2024 Nov 19.Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium:

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Academic Journal

Deletion of IKK2 in haematopoietic cells of adult mice leads to elevated interleukin-6, neutrophilia and fatal gastrointestinal inflammation.

  • Authors : Fischer KC; The Walter and Eliza Hall Institute of Medical Research, Parkville, VIC, Australia. .; Department of Medical Biology, University of Melbourne, Parkville, VIC, Australia. .

Subjects: Gastritis/Gastritis/Gastritis/*immunology ; Hematopoiesis/Hematopoiesis/Hematopoiesis/*immunology ; I-kappa B Kinase/I-kappa B Kinase/I-kappa B Kinase/*immunology

  • Source: Cell death & disease [Cell Death Dis] 2021 Jan 04; Vol. 12 (1), pp. 28. Date of Electronic Publication: 2021 Jan 04.Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101524092 Publication Model: Electronic Cited Medium:

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Academic Journal

IKKε and TBK1 prevent RIPK1 dependent and independent inflammation.

  • Authors : Eren RO; Institute for Genetics and Cologne Excellence Cluster on Cellular Stress Responses in Aging-Associated Diseases (CECAD), University of Cologne, Cologne, Germany.; Kaya GG

Subjects: I-kappa B Kinase*/I-kappa B Kinase*/I-kappa B Kinase*/metabolism ; Protein Serine-Threonine Kinases*/Protein Serine-Threonine Kinases*/Protein Serine-Threonine Kinases*/metabolism; Animals

  • Source: Nature communications [Nat Commun] 2024 Jan 02; Vol. 15 (1), pp. 130. Date of Electronic Publication: 2024 Jan 02.Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium:

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Academic Journal

Excitation-transcription coupling, neuronal gene expression and synaptic plasticity.

  • Authors : Ma H; Department of Neurobiology, Affiliated Mental Health Center and Hangzhou Seventh People's Hospital, Zhejiang University School of Medicine, Hangzhou, China. .; Liangzhu Laboratory, MOE Frontier Science Center for Brain Science and Brain-Machine Integration, State Key Laboratory of Brain-Machine Intelligence, Zhejiang University, Hangzhou, China. .

Subjects: Receptors, N-Methyl-D-Aspartate*/Receptors, N-Methyl-D-Aspartate*/Receptors, N-Methyl-D-Aspartate*/metabolism ; Neuronal Plasticity*/Neuronal Plasticity*/Neuronal Plasticity*/physiology; Humans

  • Source: Nature reviews. Neuroscience [Nat Rev Neurosci] 2023 Nov; Vol. 24 (11), pp. 672-692. Date of Electronic Publication: 2023 Sep 29.Publisher: Nature Pub. Group Country of Publication: England NLM ID: 100962781 Publication Model: Print-Electronic Cited

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Academic Journal

Prospects for gene replacement therapies in amyotrophic lateral sclerosis.

  • Authors : Giovannelli I; Sheffield Institute for Translational Neuroscience (SITraN), University of Sheffield, Sheffield, UK.; Higginbottom A

Subjects: Amyotrophic Lateral Sclerosis*/Amyotrophic Lateral Sclerosis*/Amyotrophic Lateral Sclerosis*/genetics ; Amyotrophic Lateral Sclerosis*/Amyotrophic Lateral Sclerosis*/Amyotrophic Lateral Sclerosis*/therapy ; Neurodegenerative Diseases*/Neurodegenerative Diseases*/Neurodegenerative Diseases*/therapy

  • Source: Nature reviews. Neurology [Nat Rev Neurol] 2023 Jan; Vol. 19 (1), pp. 39-52. Date of Electronic Publication: 2022 Dec 08.Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101500072 Publication Model: Print-Electronic Cited

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Academic Journal

Modelling amyotrophic lateral sclerosis in rodents.

  • Authors : Todd TW; Department of Neuroscience, Mayo Clinic Jacksonville, Jacksonville, FL, USA.; Petrucelli L

Subjects: Amyotrophic Lateral Sclerosis*/Amyotrophic Lateral Sclerosis*/Amyotrophic Lateral Sclerosis*/genetics; Animals ; Disease Models, Animal

  • Source: Nature reviews. Neuroscience [Nat Rev Neurosci] 2022 Apr; Vol. 23 (4), pp. 231-251. Date of Electronic Publication: 2022 Mar 08.Publisher: Nature Pub. Group Country of Publication: England NLM ID: 100962781 Publication Model: Print-Electronic Cited

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Academic Journal

Life, death, and autophagy in cancer: NF-κB turns up everywhere.

  • Authors : Verzella D; Department of Biotechnological and Applied Clinical Sciences (DISCAB), University of L'Aquila, 67100, L'Aquila, Italy.; Pescatore A

Subjects: NF-kappa B/NF-kappa B/NF-kappa B/*metabolism ; Neoplasms/Neoplasms/Neoplasms/*genetics; Autophagy

  • Source: Cell death & disease [Cell Death Dis] 2020 Mar 30; Vol. 11 (3), pp. 210. Date of Electronic Publication: 2020 Mar 30.Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101524092 Publication Model: Electronic Cited Medium:

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Academic Journal

Selenium in thyroid disorders - essential knowledge for clinicians.

  • Authors : Winther KH; Department of Endocrinology and Metabolism, Odense University Hospital, Odense, Denmark.; Rayman MP

Subjects: Selenium/Selenium/Selenium/*therapeutic use ; Thyroid Diseases/Thyroid Diseases/Thyroid Diseases/*drug therapy ; Thyroid Diseases/Thyroid Diseases/Thyroid Diseases/*metabolism

  • Source: Nature reviews. Endocrinology [Nat Rev Endocrinol] 2020 Mar; Vol. 16 (3), pp. 165-176. Date of Electronic Publication: 2020 Jan 30.Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101500078 Publication Model: Print-Electronic Cited

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Academic Journal

Metabolic regulation of cholestatic liver injury by D-2-hydroxyglutarate with the modulation of hepatic microenvironment and the mammalian target of rapamycin signaling.

  • Authors : Tian X; Division of Pediatric Gastroenterology and Nutrition, Xin Hua Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, 200092, China.; Department of Pediatric Surgery, Xin Hua Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, 200092, China.

Subjects: Cholestasis*/Cholestasis*/Cholestasis*/metabolism ; Biliary Atresia*/Biliary Atresia*/Biliary Atresia*/metabolism; Mice

  • Source: Cell death & disease [Cell Death Dis] 2022 Nov 26; Vol. 13 (11), pp. 1001. Date of Electronic Publication: 2022 Nov 26.Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101524092 Publication Model: Electronic Cited Medium:

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