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Academic Journal

The Carcinogenome Project: In Vitro Gene Expression Profiling of Chemical Perturbations to Predict Long-Term Carcinogenicity.

  • Authors : Li A; 1 Computational Biomedicine, Boston University School of Medicine , Boston, Massachusetts, USA.; 2 Bioinformatics Program, Boston University , Boston, Massachusetts, USA.

Subjects: Carcinogenicity Tests/Carcinogenicity Tests/Carcinogenicity Tests/*methods ; Carcinogens/Carcinogens/Carcinogens/*toxicity ; Gene Expression Profiling/Gene Expression Profiling/Gene Expression Profiling/*methods

  • Source: Environmental health perspectives [Environ Health Perspect] 2019 Apr; Vol. 127 (4), pp. 47002.Publisher: National Institute of Environmental Health Sciences Country of Publication: United States NLM ID: 0330411 Publication

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Academic Journal

Comprehensive Analyses and Prioritization of Tox21 10K Chemicals Affecting Mitochondrial Function by in-Depth Mechanistic Studies.

  • Authors : Xia M; National Center for Advancing Translational Sciences, National Institutes of Health (NIH), Department of Health and Human Services (DHHS), Bethesda, Maryland, USA.; Huang R

Subjects: Environmental Pollutants/Environmental Pollutants/Environmental Pollutants/*toxicity ; Hazardous Substances/Hazardous Substances/Hazardous Substances/*toxicity ; Membrane Potential, Mitochondrial/Membrane Potential, Mitochondrial/Membrane Potential, Mitochondrial/*drug effects

  • Source: Environmental health perspectives [Environ Health Perspect] 2018 Jul 26; Vol. 126 (7), pp. 077010. Date of Electronic Publication: 2018 Jul 26 (Print Publication: 2018).Publisher: National Institute of Environmental Health Sciences Country of Publication: United States NLM ID: 0330411 Publication

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Academic Journal

Profiling of the Tox21 chemical collection for mitochondrial function to identify compounds that acutely decrease mitochondrial membrane potential.

  • Authors : Attene-Ramos MS; National Center for Advancing Translational Sciences, National Institutes of Health (NIH), Department of Health and Human Services (DHHS), Bethesda, Maryland, USA.; Huang R

Subjects: High-Throughput Screening Assays*; Environmental Pollutants/Environmental Pollutants/Environmental Pollutants/*toxicity ; Membrane Potential, Mitochondrial/Membrane Potential, Mitochondrial/Membrane Potential, Mitochondrial/*drug effects

  • Source: Environmental health perspectives [Environ Health Perspect] 2015 Jan; Vol. 123 (1), pp. 49-56. Date of Electronic Publication: 2014 Oct 10.Publisher: National Institute of Environmental Health Sciences Country of Publication: United States NLM ID: 0330411 Publication

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Academic Journal

Endocrine-Disrupting Chemicals (EDCs): In Vitro Mechanism of Estrogenic Activation and Differential Effects on ER Target Genes.

  • Authors : Li Y; Receptor Biology Section, Laboratory of Reproductive and Developmental Toxicology, Division of Intramural Research, National Institute of Environmental Health Sciences (NIEHS), National Institutes of Health (NIH), Department of Health and Human Services (DHHS), Research Triangle Park, North Carolina 27709, USA.; Luh CJ

Subjects: Environmental Exposure*; Endocrine Disruptors/Endocrine Disruptors/Endocrine Disruptors/*pharmacology ; Estrogen Receptor alpha/Estrogen Receptor alpha/Estrogen Receptor alpha/*agonists

  • Source: Environmental health perspectives [Environ Health Perspect] 2013 Apr; Vol. 121 (4), pp. 459-66. Date of Electronic Publication: 2013 Feb 05.Publisher: National Institute of Environmental Health Sciences Country of Publication: United States NLM ID: 0330411 Publication

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Academic Journal

Differential estrogenic actions of endocrine-disrupting chemicals bisphenol A, bisphenol AF, and zearalenone through estrogen receptor α and β in vitro.

  • Authors : Li Y; Receptor Biology Section, Laboratory of Reproductive and Developmental Toxicology, National Institute of Environmental Health Sciences, National Institutes of Health, Department of Health and Human Services, Research Triangle Park, North Carolina 27709, USA.; Burns KA

Subjects: Endocrine Disruptors/Endocrine Disruptors/Endocrine Disruptors/*toxicity ; Estrogen Receptor alpha/Estrogen Receptor alpha/Estrogen Receptor alpha/*metabolism ; Estrogen Receptor beta/Estrogen Receptor beta/Estrogen Receptor beta/*metabolism

  • Source: Environmental health perspectives [Environ Health Perspect] 2012 Jul; Vol. 120 (7), pp. 1029-35. Date of Electronic Publication: 2012 Apr 11.Publisher: National Institute of Environmental Health Sciences Country of Publication: United States NLM ID: 0330411 Publication

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Academic Journal

Diastereomers of the brominated flame retardant 1,2-dibromo-4-(1,2 dibromoethyl)cyclohexane induce androgen receptor activation in the hepg2 hepatocellular carcinoma cell line and the lncap prostate cancer cell line.

  • Authors : Khalaf H; Orebro Life Science Center, Academy of Science and Technology, Orebro University, Orebro, Sweden.; Larsson A

Subjects: Cyclohexanes/Cyclohexanes/Cyclohexanes/*toxicity ; Endocrine Disruptors/Endocrine Disruptors/Endocrine Disruptors/*toxicity ; Flame Retardants/Flame Retardants/Flame Retardants/*toxicity

  • Source: Environmental health perspectives [Environ Health Perspect] 2009 Dec; Vol. 117 (12), pp. 1853-9. Date of Electronic Publication: 2009 Aug 03.Publisher: National Institute of Environmental Health Sciences Country of Publication: United States NLM ID: 0330411 Publication

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