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Academic Journal

Phase separation promotes the activity of HECT E3 ligases-A word of caution.

Subjects: *PHASE separation; *UBIQUITIN ligases; *UBIQUITIN-conjugating enzymes

  • Source: Proceedings of the National Academy of Sciences of the United States of America. 4/2/2024, Vol. 121 Issue 14, p1-2. 2p.

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WAV E3 ubiquitin ligases mediate degradation of IAA32/34 in the TMK1-mediated auxin signaling pathway during apical hook development.

Subjects: UBIQUITIN ligases; AUXIN; CELLULAR signal transduction

  • Source: Proceedings of the National Academy of Sciences of the United States of America; 4/23/2024, Vol. 121 Issue 17, p1-10, 40p

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Mechanism of catalysis, E2 recognition, and autoinhibition for the IpaH family of bacterial E3 ubiquitin ligases.

  • Authors : Keszei AF; Lunenfeld-Tanenbaum Research Institute, Mount Sinai Hospital, Toronto, ON, Canada M5G 1X5.; Department of Molecular Genetics, University of Toronto, Toronto, ON, Canada M5S 3E1.

Subjects: Bacterial Proteins/Bacterial Proteins/Bacterial Proteins/*metabolism ; Ubiquitin-Conjugating Enzymes/Ubiquitin-Conjugating Enzymes/Ubiquitin-Conjugating Enzymes/*metabolism ; Ubiquitin-Protein Ligases/Ubiquitin-Protein Ligases/Ubiquitin-Protein Ligases/*metabolism

  • Source: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2017 Feb 07; Vol. 114 (6), pp. 1311-1316. DatePublisher: National Academy of Sciences Country of Publication: United States NLM ID: 7505876 Publication Model:

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Capturing the catalytic intermediates of parkin ubiquitination.

Subjects: *UBIQUITIN ligases; *PARKIN (Protein); *UBIQUITIN-conjugating enzymes

  • Source: Proceedings of the National Academy of Sciences of the United States of America. 8/6/2024, Vol. 121 Issue 32, p1-9. 9p.

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Peptide and small molecule inhibitors of HECT-type ubiquitin ligases.

  • Authors : Mund T; Medical Research Council Laboratory of Molecular Biology, Cambridge Biomedical Campus, Cambridge CB2 0QH, United Kingdom.; Lewis MJ

Subjects: Enzyme Inhibitors/Enzyme Inhibitors/Enzyme Inhibitors/*pharmacology ; Peptides/Peptides/Peptides/*pharmacology ; Ubiquitin-Protein Ligases/Ubiquitin-Protein Ligases/Ubiquitin-Protein Ligases/*antagonists & inhibitors

  • Source: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2014 Nov 25; Vol. 111 (47), pp. 16736-41. DatePublisher: National Academy of Sciences Country of Publication: United States NLM ID: 7505876 Publication Model:

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The Legionella effector SidC defines a unique family of ubiquitin ligases important for bacterial phagosomal remodeling.

  • Authors : Hsu F; Weill Institute for Cell and Molecular Biology and Department of Molecular Biology and Genetics, Cornell University, Ithaca, NY 14853;

Subjects: Bacterial Proteins/Bacterial Proteins/Bacterial Proteins/*metabolism ; Legionella pneumophila/Legionella pneumophila/Legionella pneumophila/*enzymology ; Phagosomes/Phagosomes/Phagosomes/*metabolism

  • Source: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2014 Jul 22; Vol. 111 (29), pp. 10538-43. DatePublisher: National Academy of Sciences Country of Publication: United States NLM ID: 7505876 Publication Model:

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Structure and dynamics of a pentameric KCTD5/CUL3/Gβγ E3 ubiquitin ligase complex.

Subjects: *UBIQUITIN ligases; *PEPTIDES; *POST-translational modification

  • Source: Proceedings of the National Academy of Sciences of the United States of America. 4/23/2024, Vol. 121 Issue 17, p1-10. 10p.

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Sterol-induced degradation of HMG CoA reductase depends on interplay of two Insigs and two ubiquitin ligases, gp78 and Trc8.

  • Authors : Jo Y; Department of Molecular Genetics and Howard Hughes Medical Institute, University of Texas Southwestern Medical Center, Dallas, TX 75390-9046, USA.; Lee PC

Subjects: Hydroxymethylglutaryl CoA Reductases/Hydroxymethylglutaryl CoA Reductases/Hydroxymethylglutaryl CoA Reductases/*chemistry ; Receptors, Autocrine Motility Factor/Receptors, Autocrine Motility Factor/Receptors, Autocrine Motility Factor/*chemistry ; Receptors, Cell Surface/Receptors, Cell Surface/Receptors, Cell Surface/*chemistry

  • Source: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2011 Dec 20; Vol. 108 (51), pp. 20503-8. Date Publisher: National Academy of Sciences Country of Publication: United States NLM ID: 7505876 Publication Model:

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Cytoplasmic protein quality control degradation mediated by parallel actions of the E3 ubiquitin ligases Ubr1 and San1.

  • Authors : Heck JW; Section of Cell and Developmental Biology, Division of Biological Sciences, University of California at San Diego, La Jolla, CA 92093, USA.; Cheung SK

Subjects: Cytoplasm/Cytoplasm/Cytoplasm/*metabolism ; Saccharomyces cerevisiae/Saccharomyces cerevisiae/Saccharomyces cerevisiae/*metabolism ; Saccharomyces cerevisiae Proteins/Saccharomyces cerevisiae Proteins/Saccharomyces cerevisiae Proteins/*metabolism

  • Source: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2010 Jan 19; Vol. 107 (3), pp. 1106-11. Date Publisher: National Academy of Sciences Country of Publication: United States NLM ID: 7505876 Publication Model:

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Academic Journal

Distinct ubiquitin ligases act sequentially for RNA polymerase II polyubiquitylation.

  • Authors : Harreman M; Mechanisms of Transcription Laboratory, Clare Hall Laboratories, Cancer Research UK London Research Institute, Blanche Lane, South Mimms, Hertfordshire EN6 3LD, United Kingdom.; Taschner M

Subjects: Ubiquitination*; Polyubiquitin/Polyubiquitin/Polyubiquitin/*metabolism ; RNA Polymerase II/RNA Polymerase II/RNA Polymerase II/*metabolism

  • Source: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2009 Dec 08; Vol. 106 (49), pp. 20705-10. DatePublisher: National Academy of Sciences Country of Publication: United States NLM ID: 7505876 Publication Model:

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  • 1-10 of  1,247 results for ""UBIQUITIN ligases""