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Academic Journal

Life stage-specific poly(A) site selection regulated by Trypanosoma brucei DRBD18.

  • Authors : Bard JE; Genomics and Bioinformatics Core, University at Buffalo School of Medicine and Biomedical Sciences, Buffalo, NY 14203.; Department of Biochemistry, University at Buffalo School of Medicine and Biomedical Sciences, Buffalo, NY 14203.

Subjects: Trypanosoma brucei brucei*/Trypanosoma brucei brucei*/Trypanosoma brucei brucei*/genetics ; Trypanosoma brucei brucei*/Trypanosoma brucei brucei*/Trypanosoma brucei brucei*/metabolism ; Protozoan Proteins*/Protozoan Proteins*/Protozoan Proteins*/metabolism

  • Source: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2024 Jul 16; Vol. 121 (29), pp. e2403188121. Publisher: National Academy of Sciences Country of Publication: United States NLM ID: 7505876 Publication Model:

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Academic Journal

RAD51-mediated R-loop formation acts to repair transcription-associated DNA breaks driving antigenic variation in Trypanosoma brucei .

  • Authors : Girasol MJ; College of Medical, Veterinary and Life Sciences, School of Infection and Immunity, Wellcome Centre for Integrative Parasitology, University of Glasgow, Glasgow G12 8TA, United Kingdom.; Faculty of the MD-PhD in Molecular Medicine Program, College of Medicine, University of the Philippines Manila, Manila 1000, Philippines.

Subjects: Trypanosoma brucei brucei*; R-Loop Structures ; Antigenic Variation/Antigenic Variation/Antigenic Variation/genetics

  • Source: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2023 Nov 28; Vol. 120 (48), pp. e2309306120. Publisher: National Academy of Sciences Country of Publication: United States NLM ID: 7505876 Publication Model:

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Academic Journal

The developmental hierarchy and scarcity of replicative slender trypanosomes in blood challenges their role in infection maintenance.

  • Authors : Larcombe SD; School of Biological Sciences, Ashworth laboratories, Institute for Immunology and Infection Research, University of Edinburgh, Edinburgh EH9 3FL, United Kingdom.; Briggs EM

Subjects: Trypanosoma* ; Trypanosoma brucei brucei*/Trypanosoma brucei brucei*/Trypanosoma brucei brucei*/metabolism; Humans

  • Source: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2023 Oct 17; Vol. 120 (42), pp. e2306848120. Publisher: National Academy of Sciences Country of Publication: United States NLM ID: 7505876 Publication Model:

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Academic Journal

Single p197 molecules of the mitochondrial genome segregation system of Trypanosoma brucei determine the distance between basal body and outer membrane.

  • Authors : Aeschlimann S; Department of Chemistry, Biochemistry, and Pharmaceutical Sciences, University of Bern, Bern CH-3012, Switzerland.; Graduate School for Cellular and Biomedical Sciences, University of Bern, Bern CH-3012, Switzerland.

Subjects: DNA Replication* ; DNA, Mitochondrial*/DNA, Mitochondrial*/DNA, Mitochondrial*/genetics ; Genome, Mitochondrial*

  • Source: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2022 Oct 04; Vol. 119 (40), pp. e2204294119. Publisher: National Academy of Sciences Country of Publication: United States NLM ID: 7505876 Publication Model:

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Academic Journal

A specific basal body linker protein provides the connection function for basal body inheritance in trypanosomes.

  • Authors : Lai DH; Center for Parasitic Organisms, State Key Laboratory of Biocontrol, School of Life Sciences, Sun Yat-Sen University, 510275 Guangzhou, People's Republic of China; .

Subjects: Basal Bodies/Basal Bodies/Basal Bodies/*metabolism ; Protozoan Proteins/Protozoan Proteins/Protozoan Proteins/*metabolism ; Trypanosoma brucei brucei/Trypanosoma brucei brucei/Trypanosoma brucei brucei/*cytology

  • Source: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2021 Feb 23; Vol. 118 (8).Publisher: National Academy of Sciences Country of Publication: United States NLM ID: 7505876 Publication Model: Print Cited

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Academic Journal

Single-cell RNA sequencing of Trypanosoma brucei from tsetse salivary glands unveils metacyclogenesis and identifies potential transmission blocking antigens.

  • Authors : Vigneron A; Department of Epidemiology of Microbial Diseases, Yale School of Public Health, Yale University, New Haven, CT 06520; .

Subjects: Insect Vectors/Insect Vectors/Insect Vectors/*parasitology ; Protozoan Proteins/Protozoan Proteins/Protozoan Proteins/*genetics ; Trypanosoma brucei brucei/Trypanosoma brucei brucei/Trypanosoma brucei brucei/*genetics

  • Source: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2020 Feb 04; Vol. 117 (5), pp. 2613-2621. DatePublisher: National Academy of Sciences Country of Publication: United States NLM ID: 7505876 Publication Model:

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Academic Journal

African trypanosomes expressing multiple VSGs are rapidly eliminated by the host immune system.

  • Authors : Aresta-Branco F; Instituto de Medicina Molecular-João Lobo Antunes, Faculdade de Medicina, Universidade de Lisboa, 1649-028 Lisboa, Portugal.; Division of Immune Diversity, German Cancer Research Center, 69120 Heidelberg, Germany.

Subjects: Antigenic Variation/Antigenic Variation/Antigenic Variation/*immunology ; HMGB Proteins/HMGB Proteins/HMGB Proteins/*metabolism ; Host-Parasite Interactions/Host-Parasite Interactions/Host-Parasite Interactions/*immunology

  • Source: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2019 Oct 08; Vol. 116 (41), pp. 20725-20735. Publisher: National Academy of Sciences Country of Publication: United States NLM ID: 7505876 Publication Model:

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Academic Journal

Dynamic colocalization of 2 simultaneously active VSG expression sites within a single expression-site body in Trypanosoma brucei .

  • Authors : Budzak J; Department of Life Sciences, Imperial College London, SW7 2AZ London, United Kingdom.; Kerry LE

Subjects: Trypanosoma brucei brucei/Trypanosoma brucei brucei/Trypanosoma brucei brucei/*metabolism ; Variant Surface Glycoproteins, Trypanosoma/Variant Surface Glycoproteins, Trypanosoma/Variant Surface Glycoproteins, Trypanosoma/*metabolism; Cell Line

  • Source: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2019 Aug 13; Vol. 116 (33), pp. 16561-16570. Publisher: National Academy of Sciences Country of Publication: United States NLM ID: 7505876 Publication Model:

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Academic Journal

Flagellum couples cell shape to motility in Trypanosoma brucei .

  • Authors : Sun SY; Department of Bioengineering, James H. Clark Center, Stanford University, Stanford, CA 94305.; Department of Microbiology and Immunology, James H. Clark Center, Stanford University, Stanford, CA 94305.

Subjects: Cytoskeleton*/Cytoskeleton*/Cytoskeleton*/metabolism ; Cytoskeleton*/Cytoskeleton*/Cytoskeleton*/ultrastructure ; Flagella*/Flagella*/Flagella*/metabolism

  • Source: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2018 Jun 26; Vol. 115 (26), pp. E5916-E5925. Publisher: National Academy of Sciences Country of Publication: United States NLM ID: 7505876 Publication Model:

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Academic Journal

Global metabolic responses of mice to Trypanosoma brucei brucei infection.

  • Authors : Wang Y; Department of Biomolecular Medicine, Division of Surgery, Oncology, Reproductive Biology and Anaesthetics, Faculty of Medicine, Imperial College London, London SW7 2AZ, United Kingdom.; Utzinger J

Subjects: Trypanosoma brucei brucei*; Trypanosomiasis, African/Trypanosomiasis, African/Trypanosomiasis, African/*blood ; Trypanosomiasis, African/Trypanosomiasis, African/Trypanosomiasis, African/*urine

  • Source: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2008 Apr 22; Vol. 105 (16), pp. 6127-32. Date Publisher: National Academy of Sciences Country of Publication: United States NLM ID: 7505876 Publication Model:

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