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Academic Journal

Global patterns of antigen receptor repertoire disruption across adaptive immune compartments in COVID-19.

  • Authors : Joseph M; Peter Gorer Department of Immunobiology, School of Immunology and Microbial Sciences, King's College London, London, SE1 9RT, United Kingdom.; Immunosurveillance Laboratory, The Francis Crick Institute, London, NW1 1AT, United Kingdom.

Subjects: Adaptive Immunity*/Adaptive Immunity*/Adaptive Immunity*/genetics ; COVID-19*/COVID-19*/COVID-19*/genetics ; COVID-19*/COVID-19*/COVID-19*/immunology

  • Source: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2022 Aug 23; Vol. 119 (34), pp. e2201541119. Publisher: National Academy of Sciences Country of Publication: United States NLM ID: 7505876 Publication Model:

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Academic Journal

A set point in the selection of the αβTCR T cell repertoire imposed by pre-TCR signaling strength.

  • Authors : Bovolenta ER; Immune System Development and Function Unit, Centro Biología Molecular Severo Ochoa, Consejo Superior de Investigaciones Científicas/Universidad Autónoma de Madrid (CSIC/UAM), 28049 Madrid, Spain.; García-Cuesta EM

Subjects: Receptors, Antigen, T-Cell, alpha-beta*/Receptors, Antigen, T-Cell, alpha-beta*/Receptors, Antigen, T-Cell, alpha-beta*/genetics ; Receptors, Antigen, T-Cell, alpha-beta*/Receptors, Antigen, T-Cell, alpha-beta*/Receptors, Antigen, T-Cell, alpha-beta*/metabolism ; T-Lymphocytes*/T-Lymphocytes*/T-Lymphocytes*/immunology

  • Source: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2022 May 31; Vol. 119 (22), pp. e2201907119. Publisher: National Academy of Sciences Country of Publication: United States NLM ID: 7505876 Publication Model:

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Academic Journal

Early expression of mature αβ TCR in CD4 - CD8 - T cell progenitors enables MHC to drive development of T-ALL bearing NOTCH mutations.

  • Authors : Laffey KG; Department of Molecular Microbiology & Immunology, School of Medicine, University of Missouri-Columbia, Columbia, MO 65212.; Stiles RJ

Subjects: CD8-Positive T-Lymphocytes*/CD8-Positive T-Lymphocytes*/CD8-Positive T-Lymphocytes*/metabolism ; Precursor T-Cell Lymphoblastic Leukemia-Lymphoma*/Precursor T-Cell Lymphoblastic Leukemia-Lymphoma*/Precursor T-Cell Lymphoblastic Leukemia-Lymphoma*/genetics ; Receptor, Notch1*/Receptor, Notch1*/Receptor, Notch1*/genetics

  • Source: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2022 Jul 05; Vol. 119 (27), pp. e2118529119. Publisher: National Academy of Sciences Country of Publication: United States NLM ID: 7505876 Publication Model:

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Academic Journal

Structurally silent peptide anchor modifications allosterically modulate T cell recognition in a receptor-dependent manner.

  • Authors : Smith AR; Department of Chemistry and Biochemistry, University of Notre Dame, Notre Dame, IN 46556.; Harper Cancer Research Institute, University of Notre Dame, Notre Dame, IN 46556.

Subjects: HLA-A2 Antigen/HLA-A2 Antigen/HLA-A2 Antigen/*chemistry ; Peptides/Peptides/Peptides/*chemistry ; Receptors, Antigen, T-Cell, alpha-beta/Receptors, Antigen, T-Cell, alpha-beta/Receptors, Antigen, T-Cell, alpha-beta/*chemistry

  • Source: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2021 Jan 26; Vol. 118 (4).Publisher: National Academy of Sciences Country of Publication: United States NLM ID: 7505876 Publication Model: Print Cited

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Academic Journal

Determinants governing T cell receptor α/β-chain pairing in repertoire formation of identical twins.

  • Authors : Tanno H; Department of Chemical Engineering, University of Texas at Austin, Austin, TX 78712.; Institute for Cellular and Molecular Biology, University of Texas at Austin, Austin, TX 78712.

Subjects: Receptors, Antigen, T-Cell, alpha-beta/Receptors, Antigen, T-Cell, alpha-beta/Receptors, Antigen, T-Cell, alpha-beta/*genetics ; Twins, Monozygotic/Twins, Monozygotic/Twins, Monozygotic/*genetics; Adult

  • Source: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2020 Jan 07; Vol. 117 (1), pp. 532-540. Date Publisher: National Academy of Sciences Country of Publication: United States NLM ID: 7505876 Publication Model:

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Academic Journal

Inherent reactivity of unselected TCR repertoires to peptide-MHC molecules.

  • Authors : Krovi SH; Department of Immunology and Microbiology, University of Colorado School of Medicine, Aurora, CO 80045.; Kappler JW

Subjects: Evolution, Molecular*; Histocompatibility Antigens/Histocompatibility Antigens/Histocompatibility Antigens/*metabolism ; Receptors, Antigen, T-Cell, alpha-beta/Receptors, Antigen, T-Cell, alpha-beta/Receptors, Antigen, T-Cell, alpha-beta/*metabolism

  • Source: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2019 Oct 29; Vol. 116 (44), pp. 22252-22261. Publisher: National Academy of Sciences Country of Publication: United States NLM ID: 7505876 Publication Model:

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Academic Journal

TCRβ rearrangements without a D segment are common, abundant, and public.

  • Authors : de Greef PC; Theoretical Biology and Bioinformatics, Utrecht University, 3584 CH Utrecht, The Netherlands .; de Boer RJ

Subjects: Adaptive Immunity* ; Gene Rearrangement, beta-Chain T-Cell Antigen Receptor*; Receptors, Antigen, T-Cell, alpha-beta/Receptors, Antigen, T-Cell, alpha-beta/Receptors, Antigen, T-Cell, alpha-beta/*genetics

  • Source: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2021 Sep 28; Vol. 118 (39).Publisher: National Academy of Sciences Country of Publication: United States NLM ID: 7505876 Publication Model: Print Cited

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Academic Journal

High-resolution repertoire analysis reveals a major bystander activation of Tfh and Tfr cells.

  • Authors : Ritvo PG; Immunology-Immunopathology-Immunotherapy Laboratory, UMR_S 959, INSERM, Sorbonne Université, F-75005 Paris, France.; Saadawi A

Subjects: Germinal Center/Germinal Center/Germinal Center/*immunology ; Lymphocyte Activation/Lymphocyte Activation/Lymphocyte Activation/*immunology ; Receptors, Antigen, T-Cell, alpha-beta/Receptors, Antigen, T-Cell, alpha-beta/Receptors, Antigen, T-Cell, alpha-beta/*genetics

  • Source: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2018 Sep 18; Vol. 115 (38), pp. 9604-9609. Publisher: National Academy of Sciences Country of Publication: United States NLM ID: 7505876 Publication Model:

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Academic Journal

Distinct MHC class I-like interacting invariant T cell lineage at the forefront of mycobacterial immunity uncovered in Xenopus .

  • Authors : Edholm ES; Department of Microbiology and Immunology, University of Rochester Medical Center, Rochester, NY 14642.; Banach M

Subjects: Immunity, Cellular*; Histocompatibility Antigens Class I/Histocompatibility Antigens Class I/Histocompatibility Antigens Class I/*immunology ; Mycobacterium Infections, Nontuberculous/Mycobacterium Infections, Nontuberculous/Mycobacterium Infections, Nontuberculous/*immunology

  • Source: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2018 Apr 24; Vol. 115 (17), pp. E4023-E4031. Publisher: National Academy of Sciences Country of Publication: United States NLM ID: 7505876 Publication Model:

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Academic Journal

T cell receptor sequencing of early-stage breast cancer tumors identifies altered clonal structure of the T cell repertoire.

  • Authors : Beausang JF; Department of Bioengineering, Stanford University, Stanford, CA 94305.; Wheeler AJ

Subjects: Breast Neoplasms/Breast Neoplasms/Breast Neoplasms/*genetics ; Genes, T-Cell Receptor beta/Genes, T-Cell Receptor beta/Genes, T-Cell Receptor beta/*immunology ; Lymphocytes, Tumor-Infiltrating/Lymphocytes, Tumor-Infiltrating/Lymphocytes, Tumor-Infiltrating/*immunology

  • Source: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2017 Nov 28; Vol. 114 (48), pp. E10409-E10417. Publisher: National Academy of Sciences Country of Publication: United States NLM ID: 7505876 Publication Model:

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  • 1-10 of  297 results for ""Receptors, Antigen, T-Cell, alpha-beta""