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Academic Journal

A Novel Pyrazole Exhibits Potent Anticancer Cytotoxicity via Apoptosis, Cell Cycle Arrest, and the Inhibition of Tubulin Polymerization in Triple-Negative Breast Cancer Cells.

  • Authors : Borrego EA; The Border Biomedical Research Center, The University of Texas El Paso, El Paso, TX 79968, USA.; Department of Biological Sciences, The University of Texas El Paso, El Paso, TX 79968, USA.

Subjects: Triple Negative Breast Neoplasms*/Triple Negative Breast Neoplasms*/Triple Negative Breast Neoplasms*/pathology ; Triple Negative Breast Neoplasms*/Triple Negative Breast Neoplasms*/Triple Negative Breast Neoplasms*/drug therapy ; Triple Negative Breast Neoplasms*/Triple Negative Breast Neoplasms*/Triple Negative Breast Neoplasms*/metabolism

  • Source: Cells [Cells] 2024 Jul 20; Vol. 13 (14). Date of Electronic Publication: 2024 Jul 20.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101600052 Publication Model: Electronic Cited Medium:

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Academic Journal

Antiproliferative and Pro-Apoptotic Activity and Tubulin Dynamics Modulation of 1 H -Benzimidazol-2-yl Hydrazones in Human Breast Cancer Cell Line MDA-MB-231.

  • Authors : Yancheva D; Institute of Organic Chemistry with Centre of Phytochemistry, Bulgarian Academy of Sciences, Acad. G. Bonchev St., Build. 9, 1113 Sofia, Bulgaria.; Argirova M

Subjects: Antineoplastic Agents*/Antineoplastic Agents*/Antineoplastic Agents*/chemistry ; Antineoplastic Agents*/Antineoplastic Agents*/Antineoplastic Agents*/pharmacology ; Apoptosis*/Apoptosis*/Apoptosis*/drug effects

  • Source: Molecules (Basel, Switzerland) [Molecules] 2024 May 20; Vol. 29 (10). Date of Electronic Publication: 2024 May 20.Publisher: MDPI Country of Publication: Switzerland NLM ID: 100964009 Publication Model: Electronic Cited Medium:

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Academic Journal

Toxic Advanced Glycation End-Products Inhibit Axonal Elongation Mediated by β-Tubulin Aggregation in Mice Optic Nerves.

  • Authors : Ooi H; Graduate School and Faculty of Pharmaceutical Sciences, Suzuka University of Medical Science, 3500-3 Minamitamagaki, Suzuka 513-8670, Japan.; Furukawa A

Subjects: Tubulin*/Tubulin*/Tubulin*/metabolism ; Glycation End Products, Advanced*/Glycation End Products, Advanced*/Glycation End Products, Advanced*/metabolism ; Optic Nerve*/Optic Nerve*/Optic Nerve*/metabolism

  • Source: International journal of molecular sciences [Int J Mol Sci] 2024 Jul 05; Vol. 25 (13). Date of Electronic Publication: 2024 Jul 05.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium:

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Academic Journal

Novel Combretastatin A-4 Analogs-Design, Synthesis, and Antiproliferative and Anti-Tubulin Activity.

  • Authors : Jędrzejczyk M; Department of Medical Chemistry, Faculty of Chemistry, Adam Mickiewicz University, Uniwersytetu Poznańskiego 8, 61-614 Poznań, Poland.; Morabito B

Subjects: Tubulin*/Tubulin*/Tubulin*/metabolism ; Tubulin*/Tubulin*/Tubulin*/chemistry ; Cell Proliferation*/Cell Proliferation*/Cell Proliferation*/drug effects

  • Source: Molecules (Basel, Switzerland) [Molecules] 2024 May 08; Vol. 29 (10). Date of Electronic Publication: 2024 May 08.Publisher: MDPI Country of Publication: Switzerland NLM ID: 100964009 Publication Model: Electronic Cited Medium:

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Academic Journal

Dimeric Tubulin Modifies Mechanical Properties of Lipid Bilayer, as Probed Using Gramicidin A Channel.

  • Authors : Rostovtseva TK; Program in Physical Biology, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD 20892, USA.; Weinrich M

Subjects: Lipid Bilayers*/Lipid Bilayers*/Lipid Bilayers*/chemistry ; Tubulin*/Tubulin*/Tubulin*/metabolism; Gramicidin/Gramicidin/Gramicidin/chemistry

  • Source: International journal of molecular sciences [Int J Mol Sci] 2024 Feb 12; Vol. 25 (4). Date of Electronic Publication: 2024 Feb 12.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium:

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Academic Journal

Comparison of the Molecular Motility of Tubulin Dimeric Isoforms: Molecular Dynamics Simulations and Diffracted X-ray Tracking Study.

  • Authors : Yamane T; Graduate School of Medical Life Science, Yokohama City University, 1-7-29 Suehiro-cho, Tsurumi-ku, Yokohama 230-0045, Japan.; HPC- and AI-Driven Drug Development Platform Division, Riken Center for Computational Science, RIKEN, 1-7-22 Suehiro-cho, Tsurumi-ku, Yokohama 230-0045, Japan.

Subjects: Tubulin*/Tubulin*/Tubulin*/genetics ; Tubulin*/Tubulin*/Tubulin*/metabolism ; Molecular Dynamics Simulation*

  • Source: International journal of molecular sciences [Int J Mol Sci] 2023 Oct 21; Vol. 24 (20). Date of Electronic Publication: 2023 Oct 21.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium:

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Academic Journal

Synthesis and Biological Evaluation of Novel 2-Aroyl Benzofuran-Based Hydroxamic Acids as Antimicrotubule Agents.

  • Authors : Mariotto E; Department of Woman's and Child's Health, Hemato-Oncology Lab, University of Padova, 35128 Padova, Italy.; Laboratory of Experimental Pharmacology, Istituto di Ricerca Pediatrica (IRP), Fondazione Città della Speranza, 35128 Padova, Italy.

Subjects: Benzofurans*/Benzofurans*/Benzofurans*/pharmacology ; Benzofurans*/Benzofurans*/Benzofurans*/chemistry ; Benzofurans*/Benzofurans*/Benzofurans*/chemical synthesis

  • Source: International journal of molecular sciences [Int J Mol Sci] 2024 Jul 09; Vol. 25 (14). Date of Electronic Publication: 2024 Jul 09.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium:

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Academic Journal

Identification of Inhibitors of Tubulin Polymerization Using a CRISPR-Edited Cell Line with Endogenous Fluorescent Tagging of β-Tubulin and Histone H1.

  • Authors : Khachatryan H; Department of Pharmaceutical Sciences, Moulder Center for Drug Discovery, School of Pharmacy, Temple University, Philadelphia, PA 19140, USA.; Olszowy B

Subjects: Tubulin*/Tubulin*/Tubulin*/metabolism ; Antineoplastic Agents*/Antineoplastic Agents*/Antineoplastic Agents*/pharmacology; Humans

  • Source: Biomolecules [Biomolecules] 2023 Jan 29; Vol. 13 (2). Date of Electronic Publication: 2023 Jan 29.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101596414 Publication Model: Electronic Cited Medium:

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Academic Journal

A Novel Pathogenic TUBA1A Variant in a Croatian Infant Is Linked to a Severe Tubulinopathy with Walker-Warburg-like Features.

  • Authors : Saidin A; Epilepsy Research Group, Clinical and Health Sciences, Australian Centre for Precision Health, University of South Australia, Adelaide, SA 5000, Australia.; Novocraft Technologies, Petaling Jaya 46300, Malaysia.

Subjects: Tubulin*/Tubulin*/Tubulin*/genetics ; Walker-Warburg Syndrome*/Walker-Warburg Syndrome*/Walker-Warburg Syndrome*/genetics ; Walker-Warburg Syndrome*/Walker-Warburg Syndrome*/Walker-Warburg Syndrome*/pathology

  • Source: Genes [Genes (Basel)] 2024 Aug 05; Vol. 15 (8). Date of Electronic Publication: 2024 Aug 05.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101551097 Publication Model: Electronic Cited Medium:

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Academic Journal

Acetylated α-Tubulin and α-Synuclein: Physiological Interplay and Contribution to α-Synuclein Oligomerization.

  • Authors : Calogero AM; Department of Biosciences, Università degli Studi di Milano, 20133 Milan, Italy.; Fondazione Grigioni per il Morbo di Parkinson, 20125 Milan, Italy.

Subjects: alpha-Synuclein* ; Parkinson Disease* ; Tubulin*

  • Source: International journal of molecular sciences [Int J Mol Sci] 2023 Jul 31; Vol. 24 (15). Date of Electronic Publication: 2023 Jul 31.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium:

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  • 1-10 of  22,286 results for ""Tubulin""