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Academic Journal

Discovery of Ureido-Substituted 4-Phenylthiazole Derivatives as IGF1R Inhibitors with Potent Antiproliferative Properties.

  • Authors : Tian Y; College of Pharmacy, Jinzhou Medical University, Jinzhou 121001, China.; An N

Subjects: Receptor, IGF Type 1*/Receptor, IGF Type 1*/Receptor, IGF Type 1*/antagonists & inhibitors ; Receptor, IGF Type 1*/Receptor, IGF Type 1*/Receptor, IGF Type 1*/metabolism ; Cell Proliferation*/Cell Proliferation*/Cell Proliferation*/drug effects

  • Source: Molecules (Basel, Switzerland) [Molecules] 2024 Jun 04; Vol. 29 (11). Date of Electronic Publication: 2024 Jun 04.Publisher: MDPI Country of Publication: Switzerland NLM ID: 100964009 Publication Model: Electronic Cited Medium:

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Academic Journal

Structural Models for a Series of Allosteric Inhibitors of IGF1R Kinase.

  • Authors : Verma J; Department of Chemical Engineering and Bioengineering, University of New Hampshire, Durham, NH 03824, USA.; Vashisth H

Subjects: Models, Molecular* ; Protein Kinase Inhibitors*/Protein Kinase Inhibitors*/Protein Kinase Inhibitors*/chemistry ; Protein Kinase Inhibitors*/Protein Kinase Inhibitors*/Protein Kinase Inhibitors*/pharmacology

  • Source: International journal of molecular sciences [Int J Mol Sci] 2024 May 14; Vol. 25 (10). Date of Electronic Publication: 2024 May 14.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium:

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Academic Journal

Normal Ovarian Function in Subfertile Mouse with Amhr2- Cre-Driven Ablation of Insr and Igf1r .

  • Authors : Douglas JC; Center for Reproductive Biology, School of Molecular Biosciences, Washington State University, Pullman, WA 99164, USA.; Sekulovski N

Subjects: Ovary*/Ovary*/Ovary*/metabolism ; Ovary*/Ovary*/Ovary*/pathology ; Receptor, IGF Type 1*/Receptor, IGF Type 1*/Receptor, IGF Type 1*/genetics

  • Source: Genes [Genes (Basel)] 2024 May 12; Vol. 15 (5). Date of Electronic Publication: 2024 May 12.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101551097 Publication Model: Electronic Cited Medium:

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Academic Journal

The IGF1 Signaling Pathway: From Basic Concepts to Therapeutic Opportunities.

  • Authors : Werner H; Department of Human Molecular Genetics and Biochemistry, School of Medicine, Tel Aviv University, Tel Aviv 69978, Israel.

Subjects: Phosphatidylinositol 3-Kinases*/Phosphatidylinositol 3-Kinases*/Phosphatidylinositol 3-Kinases*/metabolism ; Receptor, IGF Type 1*/Receptor, IGF Type 1*/Receptor, IGF Type 1*/metabolism; Insulin-Like Growth Factor I/Insulin-Like Growth Factor I/Insulin-Like Growth Factor I/metabolism

  • Source: International journal of molecular sciences [Int J Mol Sci] 2023 Oct 04; Vol. 24 (19). Date of Electronic Publication: 2023 Oct 04.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium:

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Academic Journal

IGF-1 Stimulates Glycolytic ATP Production in MCF-7L Cells.

  • Authors : Rajoria B; Department of Pharmacology, University of Minnesota, Minneapolis, MN 55455, USA.; Masonic Cancer Center, University of Minnesota, Minneapolis, MN 55455, USA.

Subjects: Insulin-Like Growth Factor I*/Insulin-Like Growth Factor I*/Insulin-Like Growth Factor I*/metabolism ; Receptor, IGF Type 1*/Receptor, IGF Type 1*/Receptor, IGF Type 1*/metabolism; Tamoxifen/Tamoxifen/Tamoxifen/pharmacology

  • Source: International journal of molecular sciences [Int J Mol Sci] 2023 Jun 16; Vol. 24 (12). Date of Electronic Publication: 2023 Jun 16.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium:

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Academic Journal

Mutations in GHR and IGF1R Genes as a Potential Reason for the Lack of Catch-Up Growth in SGA Children.

  • Authors : Stróżewska W; Institute of Human Biology and Evolution, Faculty of Biology, Adam Mickiewicz University, Uniwersytetu Poznańskiego 6, 61-614 Poznan, Poland.; Durda-Masny M

Subjects: Fetal Growth Retardation*/Fetal Growth Retardation*/Fetal Growth Retardation*/genetics ; Receptor, IGF Type 1*/Receptor, IGF Type 1*/Receptor, IGF Type 1*/genetics ; Receptors, Somatotropin*/Receptors, Somatotropin*/Receptors, Somatotropin*/genetics

  • Source: Genes [Genes (Basel)] 2022 May 11; Vol. 13 (5). Date of Electronic Publication: 2022 May 11.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101551097 Publication Model: Electronic Cited Medium:

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Academic Journal

Unraveling the IGF System Interactome in Sarcomas Exploits Novel Therapeutic Options.

  • Authors : Mancarella C; Laboratory of Experimental Oncology, IRCCS Istituto Ortopedico Rizzoli, 40136 Bologna, Italy.; Morrione A

Subjects: Receptor, IGF Type 1/Receptor, IGF Type 1/Receptor, IGF Type 1/*metabolism ; Sarcoma/Sarcoma/Sarcoma/*pathology; Antibodies, Monoclonal/Antibodies, Monoclonal/Antibodies, Monoclonal/therapeutic use

  • Source: Cells [Cells] 2021 Aug 13; Vol. 10 (8). Date of Electronic Publication: 2021 Aug 13.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101600052 Publication Model: Electronic Cited Medium:

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Academic Journal

Dysregulation of miRNAs Targeting the IGF-1R Pathway in Pancreatic Ductal Adenocarcinoma.

  • Authors : Dobre M; Victor Babes National Institute of Pathology, 050096 Bucharest, Romania.; Herlea V

Subjects: Carcinoma, Pancreatic Ductal/Carcinoma, Pancreatic Ductal/Carcinoma, Pancreatic Ductal/*genetics ; MicroRNAs/MicroRNAs/MicroRNAs/*genetics ; Pancreatic Neoplasms/Pancreatic Neoplasms/Pancreatic Neoplasms/*genetics

  • Source: Cells [Cells] 2021 Jul 22; Vol. 10 (8). Date of Electronic Publication: 2021 Jul 22.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101600052 Publication Model: Electronic Cited Medium:

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Academic Journal

Lessons Learned from Targeting IGF-I Receptor in Thyroid-Associated Ophthalmopathy.

  • Authors : Janssen JAMJL; Erasmus Medical Center, Department of Internal Medicine, Dr. Molewaterplein 40, 3015 GD Rotterdam, The Netherlands.; Smith TJ

Subjects: Antibodies, Monoclonal/Antibodies, Monoclonal/Antibodies, Monoclonal/*therapeutic use ; Antibodies, Monoclonal, Humanized/Antibodies, Monoclonal, Humanized/Antibodies, Monoclonal, Humanized/*drug effects ; Graves Ophthalmopathy/Graves Ophthalmopathy/Graves Ophthalmopathy/*drug therapy

  • Source: Cells [Cells] 2021 Feb 12; Vol. 10 (2). Date of Electronic Publication: 2021 Feb 12.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101600052 Publication Model: Electronic Cited Medium:

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Academic Journal

Identification of a Resistance Mechanism to IGF-IR Targeting in Human Triple Negative MDA-MB-231 Breast Cancer Cells.

  • Authors : Tsui J; Department of Medicine, McGill University, Montreal, QC H4A 3J1, Canada.; Division of Experimental Medicine, McGill University, Montreal, QC H4A 3J1, Canada.

Subjects: Drug Resistance, Neoplasm*/Drug Resistance, Neoplasm*/Drug Resistance, Neoplasm*/drug effects; Receptor, IGF Type 1/Receptor, IGF Type 1/Receptor, IGF Type 1/*metabolism ; Triple Negative Breast Neoplasms/Triple Negative Breast Neoplasms/Triple Negative Breast Neoplasms/*pathology

  • Source: Biomolecules [Biomolecules] 2021 Apr 01; Vol. 11 (4). Date of Electronic Publication: 2021 Apr 01.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101596414 Publication Model: Electronic Cited Medium:

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  • 1-10 of  105 results for ""Receptor, IGF Type 1""