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Academic Journal

Predicting Food-Drug Interactions between Piperine and CYP3A4 Substrate Drugs Using PBPK Modeling.

  • Authors : Lin F; School of Pharmaceutical Science and Technology, Hangzhou Institute for Advanced Study, University of Chinese Academy of Sciences, Hangzhou 310058, China.; Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai 201203, China.

Subjects: Polyunsaturated Alkamides*/Polyunsaturated Alkamides*/Polyunsaturated Alkamides*/metabolism ; Piperidines*/Piperidines*/Piperidines*/pharmacokinetics ; Piperidines*/Piperidines*/Piperidines*/pharmacology

  • Source: International journal of molecular sciences [Int J Mol Sci] 2024 Oct 11; Vol. 25 (20). Date of Electronic Publication: 2024 Oct 11.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium:

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Academic Journal

DNA Methylation in the CYP3A Distal Regulatory Region (DRR) Is Associated with the Expression of CYP3A5 and CYP3A7 in Human Liver Samples.

  • Authors : Collins JM; Department of Pharmacotherapy and Translational Research, College of Pharmacy, Center for Pharmacogenomics and Precision Medicine, University of Florida, Gainesville, FL 32610, USA.; Wang D

Subjects: Cytochrome P-450 CYP3A*/Cytochrome P-450 CYP3A*/Cytochrome P-450 CYP3A*/genetics ; Cytochrome P-450 CYP3A*/Cytochrome P-450 CYP3A*/Cytochrome P-450 CYP3A*/metabolism ; DNA Methylation*

  • Source: Molecules (Basel, Switzerland) [Molecules] 2024 Nov 16; Vol. 29 (22). Date of Electronic Publication: 2024 Nov 16.Publisher: MDPI Country of Publication: Switzerland NLM ID: 100964009 Publication Model: Electronic Cited Medium:

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Academic Journal

The Effect of Metformin and Hydrochlorothiazide on Cytochrome P450 3A4 Metabolism of Ivermectin: Insights from In Silico Experimentation.

  • Authors : Mtambo TR; Department of Biochemistry and Microbiology, University of Zululand, Kwa-Dlangezwa 3886, South Africa.; Biomedical Research and Innovation Platform, South African Medical Research Council, Tygerberg 7505, South Africa.

Subjects: Cytochrome P-450 CYP3A*/Cytochrome P-450 CYP3A*/Cytochrome P-450 CYP3A*/metabolism ; Metformin*/Metformin*/Metformin*/pharmacology ; Metformin*/Metformin*/Metformin*/metabolism

  • Source: International journal of molecular sciences [Int J Mol Sci] 2024 Nov 11; Vol. 25 (22). Date of Electronic Publication: 2024 Nov 11.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium:

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Academic Journal

CYP3A4*1B but Not CYP3A5*3 as Determinant of Long-Term Tacrolimus Dose Requirements in Spanish Solid Organ Transplant Patients.

  • Authors : Concha J; Department of Pharmacy, Faculty of Health Sciences, Universidad San Jorge, E-50830 Villanueva de Gállego, Zaragoza, Spain.; Sangüesa E

Subjects: Cytochrome P-450 CYP3A*/Cytochrome P-450 CYP3A*/Cytochrome P-450 CYP3A*/genetics ; Tacrolimus*/Tacrolimus*/Tacrolimus*/administration & dosage ; Tacrolimus*/Tacrolimus*/Tacrolimus*/therapeutic use

  • Source: International journal of molecular sciences [Int J Mol Sci] 2024 Oct 21; Vol. 25 (20). Date of Electronic Publication: 2024 Oct 21.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium:

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Academic Journal

Bleeding Events Associated with Rivaroxaban Therapy in Naive Patients with Nonvalvular Atrial Fibrillation: A Longitudinal Study from a Genetic Perspective with INR Follow-Up.

  • Authors : Ain NU; Department of Pharmacology, Institute of Basic Medical Sciences, Khyber Medical University, Peshawar 25100, Khyber Pakhtunkhwa, Pakistan.; Institute of Pharmaceutical Sciences, Khyber Medical University, Peshawar 25100, Khyber Pakhtunkhwa, Pakistan.

Subjects: Rivaroxaban*/Rivaroxaban*/Rivaroxaban*/therapeutic use ; Rivaroxaban*/Rivaroxaban*/Rivaroxaban*/pharmacokinetics ; Rivaroxaban*/Rivaroxaban*/Rivaroxaban*/adverse effects

  • Source: Medicina (Kaunas, Lithuania) [Medicina (Kaunas)] 2024 Oct 18; Vol. 60 (10). Date of Electronic Publication: 2024 Oct 18.Publisher: MDPI Country of Publication: Switzerland NLM ID: 9425208 Publication Model: Electronic Cited Medium: Internet

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Academic Journal

Human Multi-Lineage Liver Organoid Model Reveals Impairment of CYP3A4 Expression upon Repeated Exposure to Graphene Oxide.

  • Authors : Romaldini A; Nanoregulatory Group, D3 PharmaChemistry, Istituto Italiano di Tecnologia, Via Morego 30, 16163 Genoa, Italy.; Spanò R

Subjects: Cytochrome P-450 CYP3A*/Cytochrome P-450 CYP3A*/Cytochrome P-450 CYP3A*/metabolism ; Cytochrome P-450 CYP3A*/Cytochrome P-450 CYP3A*/Cytochrome P-450 CYP3A*/genetics ; Organoids*/Organoids*/Organoids*/drug effects

  • Source: Cells [Cells] 2024 Sep 13; Vol. 13 (18). Date of Electronic Publication: 2024 Sep 13.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101600052 Publication Model: Electronic Cited Medium:

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Academic Journal

CYP3A-Mediated Carbon-Carbon Bond Cleavages in Drug Metabolism.

  • Authors : Zhou J; Center for Drug Discovery, Department of Pathology and Immunology, Baylor College of Medicine, Houston, TX 77030, USA.; Qin X

Subjects: Cytochrome P-450 CYP3A*/Cytochrome P-450 CYP3A*/Cytochrome P-450 CYP3A*/metabolism ; Cytochrome P-450 CYP3A*/Cytochrome P-450 CYP3A*/Cytochrome P-450 CYP3A*/chemistry ; Carbon*/Carbon*/Carbon*/metabolism

  • Source: Biomolecules [Biomolecules] 2024 Sep 05; Vol. 14 (9). Date of Electronic Publication: 2024 Sep 05.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101596414 Publication Model: Electronic Cited Medium:

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Academic Journal

Impact of CYP3A5 Polymorphisms on Pediatric Asthma Outcomes.

  • Authors : Nkoy FL; Department of Pediatrics, University of Utah School of Medicine, 100 N. Mario Capecchi Drive, Salt Lake City, UT 84113, USA.; Stone BL

Subjects: Asthma*/Asthma*/Asthma*/drug therapy ; Asthma*/Asthma*/Asthma*/genetics ; Polymorphism, Single Nucleotide*

  • Source: International journal of molecular sciences [Int J Mol Sci] 2024 Jun 14; Vol. 25 (12). Date of Electronic Publication: 2024 Jun 14.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium:

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Academic Journal

Association of CYP3A4-392A/G, CYP3A5-6986A/G, and ABCB1-3435C/T Polymorphisms with Tacrolimus Dose, Serum Concentration, and Biochemical Parameters in Mexican Patients with Kidney Transplant.

  • Authors : Alatorre-Moreno EV; Centro Universitario de Ciencias de la Salud, Departamento de Nefrología, Hospital de Especialidades, Centro Médico Nacional de Occidente, Instituto Mexicano del Seguro Social, Universidad de Guadalajara, Guadalajara 44340, Mexico.; Saldaña-Cruz AM

Subjects: Cytochrome P-450 CYP3A*/Cytochrome P-450 CYP3A*/Cytochrome P-450 CYP3A*/genetics ; Kidney Transplantation*/Kidney Transplantation*/Kidney Transplantation*/adverse effects ; Tacrolimus*/Tacrolimus*/Tacrolimus*/blood

  • Source: Genes [Genes (Basel)] 2024 Apr 16; Vol. 15 (4). Date of Electronic Publication: 2024 Apr 16.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101551097 Publication Model: Electronic Cited Medium:

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Academic Journal

Evaluation of the Lipophilicity of Angularly Condensed Diquino- and Quinonaphthothiazines as Potential Candidates for New Drugs.

  • Authors : Klimoszek D; Faculty of Pharmaceutical Sciences in Sosnowiec, Doctoral School, Medical University of Silesia in Katowice, 40-007 Katowice, Poland.; Jeleń M

Subjects: Algorithms* ; Cytochrome P-450 CYP3A*; Humans

  • Source: Molecules (Basel, Switzerland) [Molecules] 2024 Apr 08; Vol. 29 (7). Date of Electronic Publication: 2024 Apr 08.Publisher: MDPI Country of Publication: Switzerland NLM ID: 100964009 Publication Model: Electronic Cited Medium:

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  • 1-10 of  369 results for ""Cytochrome P-450 CYP3A""