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Academic Journal

Increased Trypanocidal Activity of the Salinomycin Derivative Ironomycin Is Due to ROS Production and Iron Uptake Impairment.

  • Authors : Steverding D; Bob Champion Research and Education Building, Norwich Medical School, University of East Anglia, Norwich NR4 7UQ, UK.; Rushworth SA

Subjects: Pyrans*/Pyrans*/Pyrans*/pharmacology ; Pyrans*/Pyrans*/Pyrans*/chemistry ; Reactive Oxygen Species*/Reactive Oxygen Species*/Reactive Oxygen Species*/metabolism

  • Source: Molecules (Basel, Switzerland) [Molecules] 2024 Nov 27; Vol. 29 (23). Date of Electronic Publication: 2024 Nov 27.Publisher: MDPI Country of Publication: Switzerland NLM ID: 100964009 Publication Model: Electronic Cited Medium:

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Academic Journal

Effects of Synthetic Ligustrazine-Based Chalcone Derivatives on Trypanosoma brucei brucei and Leishmania spp. Promastigotes.

  • Authors : Alkhaldi AAM; Biology Department, College of Science, Jouf University, Sakaka 72341, Saudi Arabia.

Subjects: Trypanosoma brucei brucei* ; Leishmania* ; Chalcone*/Chalcone*/Chalcone*/pharmacology

  • Source: Molecules (Basel, Switzerland) [Molecules] 2023 Jun 08; Vol. 28 (12). Date of Electronic Publication: 2023 Jun 08.Publisher: MDPI Country of Publication: Switzerland NLM ID: 100964009 Publication Model: Electronic Cited Medium:

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Academic Journal

Designing Antitrypanosomal and Antileishmanial BODIPY Derivatives: A Computational and In Vitro Assessment.

  • Authors : Gonçalves RCR; Centre of Chemistry, University of Minho, Campus de Gualtar, 4710-057 Braga, Portugal.; Advanced (Magnetic) Theranostic Nanostructures Lab, International Iberian Nanotechnology Laboratory, Av. Mestre José Veiga s/n, 4715-330 Braga, Portugal.

Subjects: Boron Compounds*/Boron Compounds*/Boron Compounds*/chemistry ; Boron Compounds*/Boron Compounds*/Boron Compounds*/pharmacology ; Boron Compounds*/Boron Compounds*/Boron Compounds*/chemical synthesis

  • Source: Molecules (Basel, Switzerland) [Molecules] 2024 Apr 30; Vol. 29 (9). Date of Electronic Publication: 2024 Apr 30.Publisher: MDPI Country of Publication: Switzerland NLM ID: 100964009 Publication Model: Electronic Cited Medium:

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Academic Journal

Preliminary Structure-Activity Relationship Study of the MMV Pathogen Box Compound MMV675968 (2,4-Diaminoquinazoline) Unveils Novel Inhibitors of Trypanosoma brucei brucei .

  • Authors : Dize D; Antimicrobial and Biocontrol Agents Unit (AmBcAU), Laboratory for Phytobiochemistry and Medicinal Plants Studies, Department of Biochemistry, Faculty of Science, University of Yaoundé I, Yaoundé P.O. Box 812, Cameroon.; Tata RB

Subjects: Trypanocidal Agents*/Trypanocidal Agents*/Trypanocidal Agents*/chemistry ; Trypanosoma*/Trypanosoma*/Trypanosoma*/metabolism ; Trypanosoma brucei brucei*

  • Source: Molecules (Basel, Switzerland) [Molecules] 2022 Oct 04; Vol. 27 (19). Date of Electronic Publication: 2022 Oct 04.Publisher: MDPI Country of Publication: Switzerland NLM ID: 100964009 Publication Model: Electronic Cited Medium:

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Academic Journal

Unique Interactions of the Small Translocases of the Mitochondrial Inner Membrane (Tims) in Trypanosoma brucei .

  • Authors : Quiñones LS; Department of Microbiology, Immunology, and Physiology, School of Medicine, Meharry Medical College, Nashville, TN 37208, USA.; Gonzalez FS

Subjects: Trypanosoma brucei brucei*/Trypanosoma brucei brucei*/Trypanosoma brucei brucei*/metabolism; Mitochondrial Membranes/Mitochondrial Membranes/Mitochondrial Membranes/metabolism ; Membrane Transport Proteins/Membrane Transport Proteins/Membrane Transport Proteins/analysis

  • Source: International journal of molecular sciences [Int J Mol Sci] 2024 Jan 24; Vol. 25 (3). Date of Electronic Publication: 2024 Jan 24.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium:

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Academic Journal

Polyaromatic Bis (indolyl)methane Derivatives with Antiproliferative and Antiparasitic Activity.

  • Authors : Gonçalves RCR; Centre of Chemistry, University of Minho, Campus of Gualtar, 4710-057 Braga, Portugal.; Advanced (Magnetic) Theranostic Nanostructures Lab, International Iberian Nanotechnology Laboratory, Av. Mestre José Veiga s/n, 4715-330 Braga, Portugal.

Subjects: Trypanosoma brucei brucei* ; Antineoplastic Agents*/Antineoplastic Agents*/Antineoplastic Agents*/pharmacology ; Neoplasms*

  • Source: Molecules (Basel, Switzerland) [Molecules] 2023 Nov 23; Vol. 28 (23). Date of Electronic Publication: 2023 Nov 23.Publisher: MDPI Country of Publication: Switzerland NLM ID: 100964009 Publication Model: Electronic Cited Medium:

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Academic Journal

In Silico and In Vitro Search for Dual Inhibitors of the Trypanosoma brucei and Leishmania major Pteridine Reductase 1 and Dihydrofolate Reductase.

  • Authors : Possart K; University of Muenster, Institute for Pharmaceutical Biology and Phytochemistry (IPBP), PharmaCampus, Corrensstrasse 48, D-48149 Muenster, Germany.; Herrmann FC

Subjects: Leishmania major* ; Trypanosoma brucei brucei* ; Trypanosomiasis, African*/Trypanosomiasis, African*/Trypanosomiasis, African*/drug therapy

  • Source: Molecules (Basel, Switzerland) [Molecules] 2023 Nov 10; Vol. 28 (22). Date of Electronic Publication: 2023 Nov 10.Publisher: MDPI Country of Publication: Switzerland NLM ID: 100964009 Publication Model: Electronic Cited Medium:

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Academic Journal

Structure-Function Analysis of RBP7910: An Editosome Z-Binding Protein in Trypanosomatids.

Subjects: DNA, Z-Form*/DNA, Z-Form*/DNA, Z-Form*/metabolism ; Trypanosoma brucei brucei*/Trypanosoma brucei brucei*/Trypanosoma brucei brucei*/genetics ; Trypanosoma brucei brucei*/Trypanosoma brucei brucei*/Trypanosoma brucei brucei*/metabolism

  • Source: Molecules (Basel, Switzerland) [Molecules] 2023 Oct 07; Vol. 28 (19). Date of Electronic Publication: 2023 Oct 07.Publisher: MDPI Country of Publication: Switzerland NLM ID: 100964009 Publication Model: Electronic Cited Medium:

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Academic Journal

Synthesis and Evaluation of Marine-Inspired Compounds Result in Hybrids with Antitrypanosomal and Antileishmanial Activities.

  • Authors : Carvalho DT; Laboratory of Organic and Pharmaceutical Chemistry, Department of Chemical Sciences, Faculty of Pharmacy, University of Porto, Rua Jorge Viterbo Ferreira 228, 4050-313 Porto, Portugal.; Laboratory of Research in Pharmaceutical Chemistry, Department of Food and Drugs, Faculty of Pharmaceutical Sciences, Federal University of Alfenas, Rua Gabriel Monteiro da Silva 700, Alfenas 37130-001, Brazil.

Subjects: Antiprotozoal Agents*/Antiprotozoal Agents*/Antiprotozoal Agents*/chemistry ; Anti-Infective Agents* ; Trypanosoma brucei brucei*

  • Source: Marine drugs [Mar Drugs] 2023 Oct 24; Vol. 21 (11). Date of Electronic Publication: 2023 Oct 24.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101213729 Publication Model: Electronic Cited Medium:

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Academic Journal

Tackling Sleeping Sickness: Current and Promising Therapeutics and Treatment Strategies.

  • Authors : Jamabo M; Biotechnology Innovation Centre, Rhodes University, Makhanda 6139, South Africa.; Mahlalela M

Subjects: Trypanosomiasis, African*/Trypanosomiasis, African*/Trypanosomiasis, African*/diagnosis ; Trypanosomiasis, African*/Trypanosomiasis, African*/Trypanosomiasis, African*/drug therapy ; COVID-19*/COVID-19*/COVID-19*/epidemiology

  • Source: International journal of molecular sciences [Int J Mol Sci] 2023 Aug 07; Vol. 24 (15). Date of Electronic Publication: 2023 Aug 07.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium:

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  • 1-10 of  670 results for ""Trypanosoma brucei brucei""